Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Charmain T Courcelle"'
Autor:
Chettar A Hoff, Sierra S Schmidt, Brandy J Hackert, Travis K Worley, Justin Courcelle, Charmain T Courcelle
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 11, Iss 4 (2021)
AbstractUV irradiation induces pyrimidine dimers that block polymerases and disrupt the replisome. Restoring replication depends on the recF2222in vivo2222
Externí odkaz:
https://doaj.org/article/49c686a7b5fc4fc0ae38a711048c67f9
Publikováno v:
DNA
Volume 1
Issue 1
Pages 3-25
Volume 1
Issue 1
Pages 3-25
In Escherichia coli, several enzymes have been identified that participate in completing replication on the chromosome, including RecG, SbcCD, ExoI, and RecBCD. However, other enzymes are likely to be involved and the precise enzymatic mechanism by w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5206b4cd631d247da7fd5eab02488914
https://doi.org/10.3390/dna1010003
https://doi.org/10.3390/dna1010003
Publikováno v:
Genes to Cells. 26:94-108
Replication initiation, elongation and completion are tightly coordinated to ensure that all sequences replicate precisely once each generation. UV-induced DNA damage disrupts replication and delays elongation, which may compromise this coordination
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2da4cbc4b7d90c89c91f7dff2f57685b
https://doi.org/10.1111/gtc.12826
https://doi.org/10.1111/gtc.12826
Autor:
Nicklas A. Hamilton, Avery E. Jehru, William N. Samples, Brian M. Wendel, Parisa D. Mokhtari, Charmain T. Courcelle, Justin Courcelle
Publikováno v:
Journal of Biological Chemistry. 299:103013
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::982400f58076abfe61403177b27a176d
https://doi.org/10.1016/j.jbc.2023.103013
https://doi.org/10.1016/j.jbc.2023.103013
Autor:
Travis K Worley, Justin Courcelle, Charmain T. Courcelle, Chettar A. Hoff, Sierra S. Schmidt, Brandy J. Hackert
Publikováno v:
G3: Genes|Genomes|Genetics
G3: Genes, Genomes, Genetics, Vol 11, Iss 4 (2021)
G3: Genes, Genomes, Genetics, Vol 11, Iss 4 (2021)
UV irradiation induces pyrimidine dimers that block polymerases and disrupt the replisome. Restoring replication depends on the recF pathway proteins which process and maintain the replication fork DNA to allow the lesion to be repaired before replic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfcd30d546fe1b5ff9ed23861b2ab5e9
https://pubmed.ncbi.nlm.nih.gov/33591320
https://pubmed.ncbi.nlm.nih.gov/33591320
Publikováno v:
Genes. 13:437
Recombination mediator proteins have come into focus as promising targets for cancer therapy, with synthetic lethal approaches now clinically validated by the efficacy of PARP inhibitors in treating BRCA2 cancers and RECQ inhibitors in treating cance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f3d6f010bfa9c6de3d998d119ff4c70
https://doi.org/10.3390/genes13030437
https://doi.org/10.3390/genes13030437
Publikováno v:
Journal of Nucleic Acids, Vol 2012 (2012)
UvrD is a DNA helicase that participates in nucleotide excision repair and several replication-associated processes, including methyl-directed mismatch repair and recombination. UvrD is capable of displacing oligonucleotides from synthetic forked DNA
Externí odkaz:
https://doaj.org/article/17cd257f20134af1bc30a6872c503e66
Autor:
Chettar A. Hoff, Natalie E. Wang, Charmain T. Courcelle, Justin Courcelle, Jessica A. Lee, Brandy J. Hackert, Corinne R. Hutfilz
Publikováno v:
J Bacteriol
Divalent metals such as iron and manganese play an important role in the cellular response to oxidative challenges and are required as cofactors by many enzymes. However, how these metals affect replication after oxidative challenge is not known. Her
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da6b2c2e51b32d471539ad149d1c74a5
https://europepmc.org/articles/PMC6872198/
https://europepmc.org/articles/PMC6872198/
Publikováno v:
Mol Microbiol
The accurate completion of DNA replication on the chromosome requires RecBCD and structure specific SbcCD ExoI nucleases. However, the substrates and mechanism by which this reaction occurs remains unknown. Here we show that these completion enzymes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ad9183afaedf81e984f397c8bfc18e1
https://pubmed.ncbi.nlm.nih.gov/30883946
https://pubmed.ncbi.nlm.nih.gov/30883946