Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Charlotte Y. Dai"'
Autor:
Emma E. Furth, Karen S. Gustafson, Charlotte Y. Dai, Steven L. Gibson, Paul Menard-Katcher, Tina Chen, Jim Koh, Greg H. Enders
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 8, Iss 6, Pp 429-436 (2006)
p16INK4a is a major tumor-suppressor protein, but its regulation and settings of fuction remain poorly understood. To explore the notion that p16 is induced in vivo in response to replicative stress, we examined p16 expression in tissues from human u
Externí odkaz:
https://doaj.org/article/d9f9ddbb80d84af1adfff90997b74486
Autor:
Greg H. Enders, Steven L. Gibson, Karen S. Gustafson, Jim Koh, Emma E. Furth, Paul Menard-Katcher, Tina Chen, Charlotte Y. Dai
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 8, Iss 6, Pp 429-436 (2006)
p16INK4a is a major tumor-suppressor protein, but its regulation and settings of fuction remain poorly understood. To explore the notion that p16 is induced in vivo in response to replicative stress, we examined p16 expression in tissues from human u
Publikováno v:
Seminars in Radiation Oncology. 16:102-110
Metastasis is the spread of tumor cells from a primary site to distant organs. It is the major cause of cancer morbidity and death. In the last few decades, significant advances have been made in surgical techniques, radiation therapy delivery, and c
Autor:
Elizabeth J. Brown, Gregory H. Enders, Xiaoming Wen, Christopher M. Wright, Savitha Bhat, Charlotte Y. Dai, Ronadip R. Banerjee, Gary D. Wu, Claire M. Steppan, Debra G. Silberg, Mitchell A. Lazar
Publikováno v:
Proceedings of the National Academy of Sciences. 98:502-506
We have identified a family of resistin-like molecules (RELMs) in rodents and humans. Resistin is a hormone produced by fat cells. RELMα is a secreted protein that has a restricted tissue distribution with highest levels in adipose tissue. Another f
Autor:
Yoshiro Niitsu, Charlotte Y. Dai, Greg H. Enders, Emma E. Furth, Rosemarie Mick, Tetsuji Takayama, Jim Koh
Publikováno v:
Gastroenterology. 119:929-942
Background & Aims: p16 INK4a is a cell cycle inhibitor and a major tumor-suppressor protein, but the regulation of p16 INK4a is poorly understood and the physiologic settings in which it exerts its antiproliferative effects are unknown. A role for p1
Autor:
Greg H. Enders, Charlotte Y. Dai
Publikováno v:
Oncogene. 19:1613-1622
The tumor suppressor p16INK4a is a potent mediator of cell cycle arrest in transient expression studies, is induced in senescing cells, and can impose morphological features of senescence. Nonetheless, it is unclear whether p16INK4a can block cell pr
Publikováno v:
Journal of Virology. 72:6228-6232
Kaposi’s sarcoma-associated herpesvirus (KSHV), or human herpesvirus 8, is a newly identified virus with tumorigenic potential. Here, we cloned and expressed the DNA polymerase (Pol-8) of KSHV and its processivity factor (PF-8). Pol-8 bound specifi
Autor:
Steven L, Gibson, Charlotte Y, Dai, Han-Woong, Lee, Ronald A, DePinho, Michael S, Gee, William M F, Lee, Emma E, Furth, Colleen, Brensinger, Greg H, Enders
Publikováno v:
Cancer research. 63(4)
The Ink4a/Arf locus is frequently methylated in colon carcinoma and other common human cancers, suggesting that the locus may play a broad, as yet poorly defined,role inhibiting tumor progression. We examined the influence of the locus in mice with m
Autor:
Ronald A. DePinho, L Gibson Steven, Greg H. Enders, Charlotte Y. Dai, Han Woong Lee, William Mf Lee, Michael S. Gee
Publikováno v:
Gastroenterology. 120:A296