Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Charlotte Spicer"'
Autor:
Charlotte Spicer, Ching‐Hua Lu, Francesco Catapano, Mariacristina Scoto, Irina Zaharieva, Andrea Malaspina, Jennifer E. Morgan, Linda Greensmith, Francesco Muntoni, Haiyan Zhou
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 8, Iss 4, Pp 866-876 (2021)
Abstract Objectives To investigate the levels of neurofilaments (NFs) in transgenic mice and patients with spinal muscular atrophy (SMA), and to evaluate their efficacy as a biomarker in SMA. Methods The levels of NF mRNA transcripts were measured by
Externí odkaz:
https://doaj.org/article/a17fa681b1774cb0a695e1e759c2ff6f
Autor:
Nicolas Granger, Alejandro Luján Feliu-Pascual, Charlotte Spicer, Sally Ricketts, Rebekkah Hitti, Oliver Forman, Joshua Hersheson, Henry Houlden
Publikováno v:
PeerJ, Vol 7, p e7983 (2019)
Background Charcot-Marie-Tooth (CMT) disease is the most common neuromuscular disorder in humans affecting 40 out of 100,000 individuals. In 2008, we described the clinical, electrophysiological and pathological findings of a demyelinating motor and
Externí odkaz:
https://doaj.org/article/9f6e8033e94d4942b625baab28368c84
Autor:
Mhoriam Ahmed, Charlotte Spicer, Jasmine Harley, J Paul Taylor, Michael Hanna, Rickie Patani, Linda Greensmith
Amyotrophic Lateral Sclerosis (ALS) and frontotemporal dementia (FTD) are now known as parts of a disease spectrum with common pathological features and genetic causes. However, as both conditions are clinically heterogeneous, patient groups may be p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::20a4016c966455a51a63b9c3b849b3db
https://doi.org/10.21203/rs.3.rs-2899750/v1
https://doi.org/10.21203/rs.3.rs-2899750/v1
Autor:
Linda Greensmith, Haiyan Zhou, Andrea Malaspina, Mariacristina Scoto, Irina Zaharieva, F. Catapano, Francesco Muntoni, Charlotte Spicer, Ching‐Hua Lu, Jennifer E. Morgan
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 8, Iss 4, Pp 866-876 (2021)
Annals of Clinical and Translational Neurology
Annals of Clinical and Translational Neurology
Objectives To investigate the levels of neurofilaments (NFs) in transgenic mice and patients with spinal muscular atrophy (SMA), and to evaluate their efficacy as a biomarker in SMA. Methods The levels of NF mRNA transcripts were measured by quantita
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef355d48c8cc78e69f429ebdee1b52b8
https://doi.org/10.1002/acn3.51336
https://doi.org/10.1002/acn3.51336
Autor:
Joshua Hersheson, Henry Houlden, Alejandro Luján Feliu-Pascual, Oliver P. Forman, Rebekkah J. Hitti, Charlotte Spicer, Nicolas Granger, Sally L. Ricketts
Publikováno v:
PeerJ
PeerJ, Vol 7, p e7983 (2019)
PeerJ, Vol 7, p e7983 (2019)
BackgroundCharcot-Marie-Tooth (CMT) disease is the most common neuromuscular disorder in humans affecting 40 out of 100,000 individuals. In 2008, we described the clinical, electrophysiological and pathological findings of a demyelinating motor and s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b56de39130002787c59220677042bcb6
Autor:
Pedro Machado, Janice L. Holton, Yunxia Wang, Linda Greensmith, Anne Weston, Jeffrey Statland, Laura Herbelin, Janelle Noel, Jianghua He, George Samandouras, Bernadett Kalmar, Michael G. Hanna, Giampietro Schiavo, A. Miller, Philip M. Gallagher, Stefen Brady, Lucy M. Collinson, Huma Sethi, Richard J. Barohn, J. Paul Taylor, Mamatha Pasnoor, April McVey, Ching-Hua Lu, Mazen M. Dimachkie, Mhoriam Ahmed, Matt Parton, Charlotte Spicer
Publikováno v:
Science translational medicine. 8(331)
Sporadic inclusion body myositis (sIBM) is the commonest severe myopathy in patients over age 50. Previous therapeutic trials have targeted the inflammatory features of sIBM, but all have failed. Since protein dyshomeostasis may also play a role in s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9741cab44e437d7db2fc386696d67794
https://pubmed.ncbi.nlm.nih.gov/27009270
https://pubmed.ncbi.nlm.nih.gov/27009270