Human serum and platelet lysate are appropriate xeno-free alternatives for clinical-grade production of human MuStem cell batches

Autor: Charlotte Saury, Aurélie Lardenois, Cindy Schleder, Isabelle Leroux, Blandine Lieubeau, Laurent David, Marine Charrier, Laëtitia Guével, Sabrina Viau, Bruno Delorme, Karl Rouger

Publikováno v: Stem Cell Research & Therapy, Vol 9, Iss 1, Pp 1-20 (2018)

Abstract Background Canine MuStem cells have demonstrated regenerative efficacy in a dog model of muscular dystrophy, and the recent characterization of human counterparts (hMuStem) has highlighted the therapeutic potential of this muscle-derived ste

Externí odkaz: https://doaj.org/article/1d0121c1cf3e4398aae9925985befa39

Skeletal Muscle Regenerative Potential of Human MuStem Cells following Transplantation into Injured Mice Muscle

Autor: Mireille Ledevin, Bruno Delorme, Laurence Dubreil, Lucie Chabrand, Gillian Butler-Browne, Armelle Magot, Yann Péréon, Sabrina Viau, Karl Rouger, Laëtitia Guével, Blandine Lieubeau, Florence Robriquet, Candice Babarit, Elisa Negroni, Vincent Mouly, Isabelle Leroux, Chantal Thorin, Antoine Hamel, Cindy Schleder, Charlotte Saury, Judith Lorant

Publikováno v: Molecular Therapy
Molecular Therapy, Cell Press, 2018, 26 (2), ⟨10.1016/j.ymthe.2017.10.013⟩
Molecular Therapy, 2018, 26 (2), ⟨10.1016/j.ymthe.2017.10.013⟩
Molecular Therapy, Nature Publishing Group, 2017, ⟨10.1016/j.ymthe.2017.10.013⟩

After intra-arterial delivery in the dystrophic dog, allogeneic muscle-derived stem cells, termed MuStem cells, contribute to long-term stabilization of the clinical status and preservation of the muscle regenerative process. However, it remains unkn

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1de191d6b2dbfee3ec1768766f5d9d14
https://hal.archives-ouvertes.fr/hal-01673455/document