Endothelial injury and decline in lung function in persons living with HIV: a prospective Danish cohort study including 698 adults

Autor: Christian Rønn, Andreas Dehlbæk Knudsen, Nicoline Stender Arentoft, Rebekka Faber Thudium, Safura-Luise Heidari, Pradeesh Sivapalan, Charlotte S. Ulrik, Thomas Benfield, Sisse Rye Ostrowski, Jens Ulrik Stæhr Jensen, Susanne D. Nielsen

Publikováno v: Frontiers in Medicine, Vol 11 (2024)

ObjectivesEndothelial injury may promote declining lung function. We aimed to investigate in well-treated persons living with HIV (PLWH) whether elevated levels of thrombomodulin (TM) and syndecan-1 (SDC1) are associated with excess lung function dec

Externí odkaz: https://doaj.org/article/1cd8f67d512d4673ab66b6ca09dc725e

Soluble urokinase plasminogen activator receptor predicts mortality in exacerbated COPD

Autor: Nina S. Godtfredsen, Ditte V. Jørgensen, Kristoffer Marsaa, Charlotte S. Ulrik, Ove Andersen, Jesper Eugen-Olsen, Line J. H. Rasmussen

Publikováno v: Respiratory Research, Vol 19, Iss 1, Pp 1-8 (2018)

Abstract Background The inflammatory biomarker soluble urokinase plasminogen activator receptor (suPAR) is elevated in severe acute and chronic medical conditions and has been associated with short-term mortality. The role of suPAR in predicting risk

Externí odkaz: https://doaj.org/article/ff7efe13ea2040bfad165c9ddd2101c1

DFV890: a new oral NLRP3 inhibitor-tested in an early phase 2a randomised clinical trial in patients with COVID-19 pneumonia and impaired respiratory function

Autor: Ildiko, Madurka, Alexander, Vishnevsky, Joan B, Soriano, Stephanus J, Gans, Danilo Joel Salazar, Ore, Adrian, Rendon, Charlotte S, Ulrik, Sushma, Bhatnagar, Srikanth, Krishnamurthy, Kirsten, Mc Harry, Tobias, Welte, Alberto A, Fernandez, Beata, Mehes, Karin, Meiser, Ewa, Gatlik, Ulrike, Sommer, Guido, Junge, Ederlon, Rezende, Felipe, Garcia

Publikováno v: Infection.

Coronavirus-associated acute respiratory distress syndrome (CARDS) has limited effective therapy to date. NLRP3 inflammasome activation induced by SARS-CoV-2 in COVID-19 contributes to cytokine storm.This randomised, multinational study enrolled hosp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5297841a9f9502c90fcb0f7a5d7836a
https://pubmed.ncbi.nlm.nih.gov/36104613

Characterization of Patients in the International Severe Asthma Registry with High Steroid Exposure Who Did or Did Not Initiate Biologic Therapy

Autor: Wenjia Chen, Mohsen Sadatsafavi, Trung N Tran, Ruth B Murray, Chong Boon Nigel Wong, Nasloon Ali, Cono Ariti, Esther Garcia Gil, Anthony Newell, Marianna Alacqua, Mona Al-Ahmad, Alan Altraja, Riyad Al-Lehebi, Mohit Bhutani, Leif Bjermer, Anne Sofie Bjerrum, Arnaud Bourdin, Lakmini Bulathsinhala, Anna von Bülow, John Busby, Giorgio Walter Canonica, Victoria Carter, George C Christoff, Borja G Cosio, Richard W Costello, J Mark FitzGerald, João A Fonseca, Kwang Ha Yoo, Liam G Heaney, Enrico Heffler, Mark Hew, Ole Hilberg, Flavia Hoyte, Takashi Iwanaga, David J Jackson, Rupert C Jones, Mariko Siyue Koh, Piotr Kuna, Désirée Larenas-Linnemann, Sverre Lehmann, Lauri A Lehtimäki, Juntao Lyu, Bassam Mahboub, Jorge Maspero, Andrew N Menzies-Gow, Concetta Sirena, Nikolaos Papadopoulos, Andriana I Papaioannou, Luis Pérez de Llano, Diahn-Warng Perng, Matthew Peters, Paul E Pfeffer, Celeste M Porsbjerg, Todor A Popov, Chin Kook Rhee, Sundeep Salvi, Camille Taillé, Christian Taube, Carlos A Torres-Duque, Charlotte S Ulrik, Seung Won Ra, Eileen Wang, Michael E Wechsler, David B Price

Publikováno v: Journal of Asthma and Allergy
Chen, W, Sadatsafavi, M, Tran, T N, Murray, R B, Wong, C B N, Ali, N, Ariti, C, Garcia Gil, E, Newell, A, Alacqua, M, Al-Ahmad, M, Altraja, A, Al-Lehebi, R, Bhutani, M, Bjermer, L, Bjerrum, A S, Bourdin, A, Bulathsinhala, L, von Bülow, A, Busby, J, Canonica, G W, Carter, V, Christoff, G C, Cosio, B G, Costello, R W, FitzGerald, J M, Fonseca, J A, Yoo, K H, Heaney, L G, Heffler, E, Hew, M, Hilberg, O, Hoyte, F, Iwanaga, T, Jackson, D J, Jones, R C, Koh, M S, Kuna, P, Larenas-Linnemann, D, Lehmann, S, Lehtimäki, L A, Lyu, J, Mahboub, B, Maspero, J, Menzies-Gow, A N, Sirena, C, Papadopoulos, N, Papaioannou, A I, Pérez de Llano, L & Perng, D-W 2022, ' Characterization of patients in the international severe asthma registry with high steroid exposure who did or did not initiate biologic therapy ', Journal of Asthma and Allergy, vol. 15, pp. 1491-1510 . https://doi.org/10.2147/JAA.S377174
Chen, W, Sadatsafavi, M, Tran, T N, Murray, R B, Wong, C B N, Ali, N, Ariti, C, Gil, E G, Newell, A, Alacqua, M, Al-Ahmad, M, Altraja, A, Al-Lehebi, R, Bhutani, M, Bjermer, L, Bjerrum, A S, Bourdin, A, Bulathsinhala, L, Von Bülow, A, Busby, J, Canonica, G W, Carter, V, Christoff, G C, Cosio, B G, Costello, R W, Fitzgerald, J M, Fonseca, J A, Ha Yoo, K, Heaney, L G, Heffler, E, Hew, M, Hilberg, O, Hoyte, F, Iwanaga, T, Jackson, D J, Jones, R C, Koh, M S, Kuna, P, Larenas-Linnemann, D, Lehmann, S, Lehtimäki, L A, Lyu, J, Mahboub, B, Maspero, J, Menzies-Gow, A N, Sirena, C, Papadopoulos, N, Papaioannou, A I, De Llano, L P, Perng, D W, Peters, M, Pfeffer, P E, Porsbjerg, C M, Popov, T A, Rhee, C K, Salvi, S, Taillé, C, Taube, C, Torres-Duque, C A, Ulrik, C S, Won Ra, S, Wang, E, Wechsler, M E & Price, D B 2022, ' Characterization of Patients in the International Severe Asthma Registry with High Steroid Exposure Who Did or Did Not Initiate Biologic Therapy ', Journal of Asthma and Allergy, vol. 15, pp. 1491-1510 . https://doi.org/10.2147/JAA.S377174

Wenjia Chen,1 Mohsen Sadatsafavi,2 Trung N Tran,3 Ruth B Murray,4 Chong Boon Nigel Wong,1 Nasloon Ali,4,5 Cono Ariti,4,5 Esther Garcia Gil,6 Anthony Newell,5,7 Marianna Alacqua,8 Mona Al-Ahmad,9 Alan Altraja,10 Riyad Al-Lehebi,11,12 Mohit Bhutani,13

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c897e55570afd17924c867ba91c36a63
https://hdl.handle.net/11250/3043986

Early life exposures and risk of atopy among Danish children

Autor: Simon F, Thomsen, Charlotte S, Ulrik, Celeste, Porsbjerg, Vibeke, Backer

Publikováno v: Allergy and asthma proceedings. 27(2)

A large proportion of atopy develops in childhood and early life exposures are suspected to play a considerable role in the inception. The aim of this study was to examine the association between early life exposures and development of atopic disease

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::610f41294ffd58bbd37a799f1a3a0c3f
https://pubmed.ncbi.nlm.nih.gov/16724627