Thiopurine Derivative-Induced Fpg/Nei DNA Glycosylase Inhibition: Structural, Dynamic and Functional Insights

Autor: Zahira Tber, Vincent Roy, Charlotte Rieux, Vincent Aucagne, Stéphane Goffinont, Luigi A. Agrofoglio, Bertrand Castaing, Franck Coste, Martine Guérin, Stéphane Bourg, Norbert Garnier, Virginie Gaudon, J. Cros, Artur Biela

Publikováno v: International Journal of Molecular Sciences
International Journal of Molecular Sciences, MDPI, 2020, 21 (6), pp.2058. ⟨10.3390/ijms21062058⟩
International Journal of Molecular Sciences, Vol 21, Iss 6, p 2058 (2020)
Volume 21
Issue 6
International Journal of Molecular Sciences, 2020, 21 (6), pp.2058. ⟨10.3390/ijms21062058⟩
'International Journal of Molecular Sciences ', vol: 21, pages: 2058-1-2058-28 (2020)

International audience; DNA glycosylases are emerging as relevant pharmacological targets in inflammation, cancer and neurodegenerative diseases. Consequently, the search for inhibitors of these enzymes has become a very active research field. As a c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e27c1dec631cb5118943b0f3c5fa913
https://doi.org/10.3390/ijms21062058