Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Charlotte R. Flavell"'
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 13 (2019)
Reconsolidation normally functions to update and maintain memories in the long-term. However, this process can be disrupted pharmacologically to weaken memories. Exploiting such experimental amnesia to disrupt the maladaptive reward memories underpin
Externí odkaz:
https://doaj.org/article/6975d4825e9544f495b3c021d3f04747
Publikováno v:
Learn Mem
The efficacy of pharmacological disruption of fear memory reconsolidation depends on several factors, including memory strength and age. We built on previous observations that systemic treatment with the nootropic nefiracetam potentiates cued fear me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e96f8271fc60458807e1c18262dd44c6
https://doi.org/10.1101/lm.052167.120
https://doi.org/10.1101/lm.052167.120
Publikováno v:
Psychopharmacology
Rationale Pharmacological targeting of memory reconsolidation is a promising therapeutic strategy for the treatment of fear memory-related disorders. However, the success of reconsolidation-based approaches depends upon the effective destabilisation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ed4ef8b96136606ab59c3351524912c
http://europepmc.org/articles/PMC6892761
http://europepmc.org/articles/PMC6892761
The efficacy of pharmacological disruption of fear memory reconsolidation depends on several factors, including memory strength and age. We built on previous observations that systemic treatment with the nootropic nefiracetam potentiates cued fear me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35802b39f2498db77d2992fa35ade679
https://doi.org/10.1101/2020.05.11.088922
https://doi.org/10.1101/2020.05.11.088922
Publikováno v:
Frontiers in Behavioral Neuroscience
Frontiers in Behavioral Neuroscience, Vol 13 (2019)
Frontiers in Behavioral Neuroscience, Vol 13 (2019)
Reconsolidation normally functions to update and maintain memories in the long-term. However, this process can be disrupted pharmacologically to weaken memories. Exploiting such experimental amnesia to disrupt the maladaptive reward memories underpin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5929084a86454153a6d79f60001b5f1f
https://doi.org/10.3389/fnbeh.2019.00242
https://doi.org/10.3389/fnbeh.2019.00242
Autor:
Charlotte R. Flavell, Lee Jlc
Pharmacological targeting of memory reconsolidation is a promising therapeutic strategy for the treatment of fear memory-related disorders. However, the success of reconsolidation-based approaches depends upon the effective destabilisation of the fea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3f702bbe99c6404fab2f294b65eb7ed
Autor:
Kai Rong Tay, Maria Wimber, Charlotte R. Flavell, Jonathan L.C. Lee, Lindsey de Freitas Cassini
Publikováno v:
The Journal of Neuroscience
Memory reconsolidation is hypothesized to be a mechanism by which memories can be updated with new information. Such updating has previously been shown to weaken memory expression or change the nature of the memory. Here we demonstrate that retrieval
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e47faf45e5cfa23ee61859e2b1069a1
https://eprints.gla.ac.uk/225925/1/225925.pdf
https://eprints.gla.ac.uk/225925/1/225925.pdf
Publikováno v:
The Journal of Comparative Neurology
The gracile nucleus (GN) and lateral part of rostral dorsal accessory olive (rDAO) are important relays for indirect, postsynaptic dorsal column, and direct ascending pathways, respectively, that terminate as climbing fibers in the “hindlimb-receiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d5327f661a50751d4b76d84b0f6e896
http://europepmc.org/articles/PMC4282304
http://europepmc.org/articles/PMC4282304
Publikováno v:
Neurobiology of Learning and Memory. 104:25-31
When memories are retrieved, they can enter a labile state during which the memory may be modified and subsequently restabilized through the process of reconsolidation. However, this does not occur in all situations, and certain "boundary conditions"
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84b37b47d5c98f3c7a06603a902c056e
https://doi.org/10.1016/j.nlm.2013.04.009
https://doi.org/10.1016/j.nlm.2013.04.009
Publikováno v:
Learning & Memory. :256-263
The basolateral amygdala (BLA) and the dorsal hippocampus (dHPC) are both structures with key roles in contextual fear conditioning. During fear conditioning, it is postulated that contextual representations of the environment are formed in the hippo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03acbd01bbcd36937d86d9afbae74d1e
https://doi.org/10.1101/lm.025403.111
https://doi.org/10.1101/lm.025403.111