Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Charlotte Lomax"'
Autor:
Clarice Noleto-Dias, Charlotte Lomax, Alice Bellisai, Gianluca Ruvo, Claudia Harflett, William J. Macalpine, Steven J. Hanley, Michael H. Beale, Jane L. Ward
Publikováno v:
Plants, Vol 13, Iss 12, p 1609 (2024)
An investigation of phenolic glycosides extracted from Salix germplasm revealed that arbusculoidin (benzyl 1-O-β-d-glucopyranosyl-1-hydroxy-6-oxo-2-cyclohexenyl carboxylate) and its enolic 6-glycoside isomer, isoarbusculoidin, are widespread across
Externí odkaz:
https://doaj.org/article/17404a664dbc4798ae11fa5ac0721b52
Autor:
Gunna Christiansen, Daniel E. Otzen, Jane L. Ward, Duncan S. Sutherland, Hossein Mohammad-Beigi, Hoda Eskandari, Clarice Noleto-Dias, Ahmed F. Tawfike, Mustafa Ghanadian, Charlotte Lomax
Publikováno v:
Eskandari, H, Ghanadian, M, Noleto-Dias, C, Lomax, C, Tawfike, A, Christiansen, G, Sutherland, D S, Ward, J L, Mohammad-Beigi, H & Otzen, D E 2020, ' Inhibitors of α-Synuclein fibrillation and oligomer toxicity in Rosa damascena : the all-pervading powers of flavonoids and phenolic glycosides ', ACS Chemical Neuroscience, vol. 11, no. 19, pp. 3161–3173 . https://doi.org/10.1021/acschemneuro.0c00528
There is an intense search for natural compounds that can inhibit the oligomerization and fibrillation of α-Synuclein (α-Syn), whose aggregation is key to the development of Parkinson's disease (PD). Rosa damascena is a medicinal herb widely used i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd0a703fd06143b1c76e7f453f9ab25f
https://doi.org/10.1021/acschemneuro.0c00528
https://doi.org/10.1021/acschemneuro.0c00528
Autor:
Yanqi Wu, Charlotte Lomax, W. J. Macalpine, Delia I. Corol, Hannah Onafuye, Mark N. Wass, Claudia Harflett, Jindrich Cinatl, Jane L. Ward, Michael H. Beale, Martin Michaelis
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-15 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-15 (2020)
Willow (Salix spp.) is well known as a source of medicinal compounds, the most famous being salicin, the progenitor of aspirin. Here we describe the isolation, structure determination, and anti-cancer activity of a cyclodimeric salicinoid (miyabeacin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d1421048e2d28a84034109aba8d9610
https://doi.org/10.1038/s41598-020-63349-1
https://doi.org/10.1038/s41598-020-63349-1
Autor:
Satish Kulasekaran, Femke de Jong, Gianluca Ruvo, Sergio Cerezo-Medina, Amelie Rendour, Steven J. Hanley, Charlotte Lomax, Michael H. Beale, Claudia Harflett, Jane L. Ward
The salicinoids are phenolic glycosides that are characteristic secondary metabolites of the Salicaceae, particularly willows and poplars. Despite the well-known pharmacology of salicin, that led to the development of aspirin >100 years ago, the bios
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8437678ed8296fdaab5e7d59dbc20909
Autor:
Gunna Christiansen, Daniel E. Otzen, Hossein Mohammad-Beigi, Hoda Eskandari, Cagla Sahin, Mehdi Hosseini-Mazinani, Alireza Amiri-Nowdijeh, Nicholas P. Schafer, Jane L. Ward, Charlotte Lomax, Ian M. Møller, Dina Morshedi, Farhang Aliakbari, Ahmed F. Tawfike
Publikováno v:
Mohammad-Beigi, H, Aliakbari, F, Sahin, C, Lomax, C, Tawfike, A, Schafer, N P, Amiri-Nowdijeh, A, Eskandari, H, Møller, I M, Hosseini-Mazinani, M, Christiansen, G, Ward, J L, Morshedi, D & Otzen, D E 2019, ' Oleuropein derivatives from olive fruit extracts reduce α-synuclein fibrillation and oligomer toxicity ' The Journal of biological chemistry . https://doi.org/10.1074/jbc.RA118.005723
Mohammad-Beigi, H, Aliakbari, F, Sahin, C, Lomax, C, Tawfike, A, P. Schafer, N, Amiri-Nowdijeh, A, Eskandari, H, Møller, I M, Hosseini-Mazinani, M, Christiansen, G, Ward, J L, Morshedi, D & Otzen, D 2019, ' Oleuropein derivatives from olive fruit extracts reduce α-synuclein fibrillation and oligomer toxicity ', Journal of Biological Chemistry, vol. 294, no. 11, pp. 4215-4232 . https://doi.org/10.1074/jbc.RA118.005723
Mohammad-Beigi, H, Aliakbari, F, Sahin, C, Lomax, C, Tawfike, A, P. Schafer, N, Amiri-Nowdijeh, A, Eskandari, H, Møller, I M, Hosseini-Mazinani, M, Christiansen, G, Ward, J L, Morshedi, D & Otzen, D 2019, ' Oleuropein derivatives from olive fruit extracts reduce α-synuclein fibrillation and oligomer toxicity ', Journal of Biological Chemistry, vol. 294, no. 11, pp. 4215-4232 . https://doi.org/10.1074/jbc.RA118.005723
Aggregation of α-synuclein (αSN) is implicated in neuronal degeneration in Parkinson's disease and has prompted searches for natural compounds inhibiting αSN aggregation and reducing its tendency to form toxic oligomers. Oil from the olive tree (O
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a782b93d59484a9671c3d48dcb0a075
https://pure.au.dk/portal/da/publications/oleuropein-derivatives-from-olive-fruit-extracts-reduce-synuclein-fibrillation-and-oligomer-toxicity(3b145a21-d995-4833-825d-8ec555acb8df).html
https://pure.au.dk/portal/da/publications/oleuropein-derivatives-from-olive-fruit-extracts-reduce-synuclein-fibrillation-and-oligomer-toxicity(3b145a21-d995-4833-825d-8ec555acb8df).html
Autor:
Jizhong Zhou, Liyou Wu, Fang-Jie Zhao, Andrew A. Meharg, Wenju Liu, Charlotte Lomax, Jinbo Xiong, Anthony J. Miller, Kai Xue, Steve P. McGrath
Publikováno v:
New Phytologist. 193:665-672
• Inorganic arsenic (iAs) is a ubiquitous human carcinogen, and rice (Oryza sativa) is the main contributor to iAs in the diet. Methylated pentavalent As species are less toxic and are routinely found in plants; however, it is currently unknown whe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4413254089f859ffba89f670d770f47
https://doi.org/10.1111/j.1469-8137.2011.03956.x
https://doi.org/10.1111/j.1469-8137.2011.03956.x