Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Charlotte Linke"'
Autor:
Charlotte Linke, Thomas Freitag, Christin Riess, Jana Vanessa Scheffler, Katharina del Moral, Nina Schoenwaelder, Tomas Fiedler, Adina Fiebig, Philipp Kaps, Daniel Dubinski, Björn Schneider, Wendy Bergmann, Carl Friedrich Classen, Claudia Maletzki
Publikováno v:
Cancer Cell International, Vol 23, Iss 1, Pp 1-18 (2023)
Abstract Background Arginine auxotrophy constitutes a shortcoming for ~ 30% of glioblastoma multiforme (GBM). Indeed, arginine-depleting therapy using arginine deiminase from Streptococcus pyogenes (SpyADI) has proven activity against GBM in preclini
Externí odkaz:
https://doaj.org/article/b688d5f6f21b43c69fa8ffaf7d1c4143
Autor:
Christin Riess, Katharina del Moral, Adina Fiebig, Philipp Kaps, Charlotte Linke, Burkhard Hinz, Anne Rupprecht, Marcus Frank, Tomas Fiedler, Dirk Koczan, Sascha Troschke-Meurer, Holger N. Lode, Nadja Engel, Thomas Freitag, Carl Friedrich Classen, Claudia Maletzki
Publikováno v:
Cell Death and Disease, Vol 13, Iss 6, Pp 1-14 (2022)
The complex effects of combined CDki/SPyADI application on arginine-auxotrophic glioblastoma multiforme cells. CDki/SPyADI combination therapy impairs cell proliferation, invasiveness, gene expression, induces mitochondrial impairment, and vacuole fo
Externí odkaz:
https://doaj.org/article/e4a237d57e9d4704bd9c0f69a431ba27
Autor:
Christin Riess, Dirk Koczan, Björn Schneider, Charlotte Linke, Katharina del Moral, Carl Friedrich Classen, Claudia Maletzki
Publikováno v:
Cell Death Discovery, Vol 7, Iss 1, Pp 1-15 (2021)
Abstract Current therapeutic approaches have met limited clinical success for glioblastoma multiforme (GBM). Since GBM harbors genomic alterations in cyclin-dependent kinases (CDKs), targeting these structures with specific inhibitors (CDKis) is prom
Externí odkaz:
https://doaj.org/article/68fa0d1afbb74b2487585beff34bf5af
Autor:
Christin Riess, Katharina del Moral, Adina Fiebig, Philipp Kaps, Charlotte Linke, Burkhard Hinz, Anne Rupprecht, Markus Frank, Tomas Fiedler, Dirk Koczan, Sascha Troschke-Meurer, Holger N Lode, Nadja Engel, Carl Friedrich Classen, Claudia Maletzki
Publikováno v:
Neuro-Oncology. 24:i62-i63
INTRODUCTION/BACKGROUND: Glioblastoma multiforme show constitutive activation of cyclin-dependent kinases (CDKs) or arginine auxotrophy. This renders tumor cells vulnerable towards arginine-depleting substances, such as arginine deiminase from Strept
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::686d1cc9bda3a10ab3f27c0a2b086190
https://doi.org/10.1093/neuonc/noac079.228
https://doi.org/10.1093/neuonc/noac079.228
Publikováno v:
BMJ Open
OBJECTIVES: In Germany, healthcare for people lacking legal residency status and European Union citizens without health insurance is often provided by non-governmental organisations. Scientific studies assessing the situation of the patients with chr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d285ec79704016ccdc860980ec87f173
https://doi.org/10.1136/bmjopen-2018-025018
https://doi.org/10.1136/bmjopen-2018-025018
