Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Charlotte L. Barney"'
Publikováno v:
ChemInform. 22
Ketones and α-trifluoromethylketones were converted to primary, secondary, and tertiary amines in good to excellent yields by a reductive amination procedure utilizing TiCl 4 /NaCNBH 3 . The method provides the first direct route to α-trifluorometh
Publikováno v:
Tetrahedron Letters. 31:5547-5550
Ketones and α-trifluoromethylketones were converted to primary, secondary, and tertiary amines in good to excellent yields by a reductive amination procedure utilizing TiCl 4 /NaCNBH 3 . The method provides the first direct route to α-trifluorometh
Autor:
James R. McCarthy, P. J. Shea, Jeffrey P. Whitten, Takashi Kariya, Donald P. Matthews, Charlotte L. Barney, Marcia A. Ertel, Therese Burkhard, Franklin N. Marshall, P. R. Kastner
Publikováno v:
Journal of Medicinal Chemistry. 33:317-327
A series of substituted 2,2'-bi-1H-imidazoles and related analogues was synthesized and evaluated for inotropic activity. Structure-activity relationship studies based on a nonclassical bioisosteric approach indicated the necessity of a cyano group o
Publikováno v:
Tetrahedron Letters. 31:973-976
The first examples of the addition of PhSeF to olefins to yield β-fluoro phenylselenides ( 2 ) are reported. β-Fluoro phenylselenides ( 2 ) obtained from terminal olefins were converted to the title vinyl fluorides 3 on treatment with ozone, wherea
Publikováno v:
ChemInform. 21
Autor:
P. J. Shea, Franklin N. Marshall, Charlotte L. Barney, Donald P. Matthews, Marcia A. Ertel, Takashi Kariya, P. R. Kastner, James R. McCarthy, Therese Burkhard, Jeffrey P. Whitten
Publikováno v:
ChemInform. 21
A series of substituted 2,2'-bi-1H-imidazoles and related analogues was synthesized and evaluated for inotropic activity. Structure-activity relationship studies based on a nonclassical bioisosteric approach indicated the necessity of a cyano group o
Publikováno v:
ChemInform. 21
A convenient synthesis of a novel class of kynureninase inhibitors, difluoroketoamino acid ( 11 ) is described.
Publikováno v:
Tetrahedron Letters. 28:2207-2210
Copper or nickel catalyzed substitution of Grignard reagents on the bis-trimethylsilyl protected 4-methoxy-2-butynylamine ( 2 ) provides β-substituted-α-allenyl primary amines ( 3 ) in high yield.
Publikováno v:
Tetrahedron Letters. 20:2241-2244
Several imines have been prepared from methacrolein dimer. Thermal rearrangement of these molecules resulted in the formation of N-substituted tetrahydropyridines.
Publikováno v:
Tetrahedron Letters. 30:3649-3652
A convenient synthesis of a novel class of kynureninase inhibitors, difluoroketoamino acid ( 11 ) is described.