Zobrazeno 1 - 10 of 37 pro vyhledávání: '"Charlotte Klein"'
1
Akademický článek
On the Value of In Vitro Cell Systems for Mechanobiology from the Perspective of Yes-Associated Protein/Transcriptional Co-Activator with a PDZ-Binding Motif and Focal Adhesion Kinase and Their Involvement in Wound Healing, Cancer, Aging, and Senescence
Autor: Thorsten Steinberg, Martin Philipp Dieterle, Imke Ramminger, Charlotte Klein, Julie Brossette, Ayman Husari, Pascal Tomakidi
Publikováno v: International Journal of Molecular Sciences, Vol 24, Iss 16, p 12677 (2023)
Mechanobiology comprises how cells perceive different mechanical stimuli and integrate them into a process called mechanotransduction; therefore, the related mechanosignaling cascades are generally important for biomedical research. The ongoing disco
Externí odkaz: https://doaj.org/article/2fdeb8221d9d43a4bac0a48f5d5e9bcd
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2
Akademický článek
Retention in the Austrian opioid agonist treatment system: a national prospective cohort study
Autor: Martin Busch, Charlotte Klein, Alfred Uhl, Hans Haltmayer, Maurice Cabanis, Jean Nicolas Westenberg, Marc Vogel, R. Michael Krausz
Publikováno v: Harm Reduction Journal, Vol 18, Iss 1, Pp 1-10 (2021)
Abstract Background Retention in care is a prerequisite for successful recovery, especially for a chronic condition like opioid dependence. Though retention varies greatly depending on the different substitution medication and treatment model, treatm
Externí odkaz: https://doaj.org/article/f8af36e1cd20428bbf6c9db3b5c67ebb
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3
Akademický článek
Indomethacin promotes survival of new neurons in the adult murine hippocampus accompanied by anti-inflammatory effects following MPTP-induced dopamine depletion
Autor: Elisabeth G. Hain, Maria Sparenberg, Justyna Rasińska, Charlotte Klein, Levent Akyüz, Barbara Steiner
Publikováno v: Journal of Neuroinflammation, Vol 15, Iss 1, Pp 1-16 (2018)
Abstract Background Parkinson’s disease (PD) is characterized by dopaminergic cell loss and inflammation in the substantia nigra (SN) leading to motor deficits but also to hippocampus-associated non-motor symptoms such as spatial learning and memor
Externí odkaz: https://doaj.org/article/1fe648e26a0a4e268861c4abc74ddc7b
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4
Akademický článek
Dopaminergic Neurodegeneration in the Mouse Is Associated with Decrease of Viscoelasticity of Substantia Nigra Tissue.
Autor: Elisabeth G Hain, Charlotte Klein, Tonia Munder, Juergen Braun, Kerstin Riek, Susanne Mueller, Ingolf Sack, Barbara Steiner
Publikováno v: PLoS ONE, Vol 11, Iss 8, p e0161179 (2016)
The biomechanical properties of brain tissue are altered by histopathological changes due to neurodegenerative diseases like Parkinson's disease (PD). Such alterations can be measured by magnetic resonance elastography (MRE) as a non-invasive techniq
Externí odkaz: https://doaj.org/article/1e30e58d7ba6486e92fbe5d822048185
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5
Akademický článek
Enhanced adult neurogenesis increases brain stiffness: in vivo magnetic resonance elastography in a mouse model of dopamine depletion.
Autor: Charlotte Klein, Elisabeth G Hain, Juergen Braun, Kerstin Riek, Susanne Mueller, Barbara Steiner, Ingolf Sack
Publikováno v: PLoS ONE, Vol 9, Iss 3, p e92582 (2014)
The mechanical network of the brain is a major contributor to neural health and has been recognized by in vivo magnetic resonance elastography (MRE) to be highly responsive to diseases. However, until now only brain softening was observed and no mech
Externí odkaz: https://doaj.org/article/1d05659419fa46749eab3c5960e61264
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6
Transposon-mediated glial cell line-derived neurotrophic factor overexpression in human adipose tissue-derived mesenchymal stromal cells: A potential approach for neuroregenerative medicine?
Autor: Justyna Rasińska, Charlotte Klein, Laura Stahn, Felix Maidhof, Anna Pfeffer, Stefanie Schreyer, Manfred Gossen, Andreas Kurtz, Barbara Steiner, Shabnam Hemmati‐Sadeghi
Publikováno v: Rasińska, J.; Klein, C.; Stahn, L.; Maidhof, F.; Pfeffer, A.; Schreyer, S.; Gossen, M.; Kurtz, A.; Steiner, B.; Hemmati-Sadeghi, S.: Transposon-mediated glial cell line-derived neurotrophic factor overexpression in human adipose tissue-derived mesenchymal stromal cells: A potential approach for neuroregenerative medicine?. In: Journal of Tissue Engineering and Regenerative Medicine. Vol. 16 (2022) 6, 515-529. (DOI: /10.1002/term.3296)
Glial cell line-derived neurotrophic factor (GDNF) has neuroprotective effects and may be a promising candidate for regenerative strategies focusing on neurodegenerative diseases. As GDNF cannot cross the blood–brain barrier to potentially regenera
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1b632b30fa4826a868091ffa27cd375
https://pubmed.ncbi.nlm.nih.gov/35278347
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7
Akademický článek
Discovery of the first hydrothermal field along the 500-km-long Knipovich Ridge offshore Svalbard (the Jøtul field)
Autor: Gerhard Bohrmann, Katharina Streuff, Miriam Römer, Stig-Morten Knutsen, Daniel Smrzka, Jan Kleint, Aaron Röhler, Thomas Pape, Nils Rune Sandstå, Charlotte Kleint, Christian Hansen, Christian dos Santos Ferreira, Maren Walter, Gustavo Macedo de Paula Santos, Wolfgang Bach
Publikováno v: Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Oceanic spreading centers north of Iceland are characterized by ultraslow spreading rates, and related hydrothermal activity has been detected in the water column and at the seafloor along nearly all ridge segments. An exception is the 500-k
Externí odkaz: https://doaj.org/article/83a9cc8d14d440a5ba1c261e522a6286
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8
Retention in the Austrian opioid agonist treatment system: a national prospective cohort study
Autor: Jean Nicolas Westenberg, Maurice Cabanis, Martin Busch, R. Michael Krausz, Hans Haltmayer, Alfred Uhl, Marc Vogel, Charlotte Klein
Publikováno v: Harm Reduction Journal, Vol 18, Iss 1, Pp 1-10 (2021)
Harm Reduction Journal
BackgroundRetention in care is a prerequisite for successful recovery, especially for a chronic condition like opioid dependence. Though retention varies greatly depending on the different substitution medication and treatment model, treatment retent
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c52b80c3df54441a7d2627a01bcfedad
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9
Chia seeds as a potential cognitive booster in the APP23 Alzheimer’s disease model
Autor: Stefanie Schreyer, Charlotte Klein, Anna Pfeffer, Justyna Rasińska, Laura Stahn, Karlotta Knuth, Basim Abuelnor, Alina Elisabeth Catharina Panzel, André Rex, Stefan Koch, Shabnam Hemmati-Sadeghi, Barbara Steiner
Publikováno v: Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-16 (2020)
Glucose hypometabolism potentially contributes to Alzheimer’s disease (AD) and might even represent an underlying mechanism. Here, we investigate the relationship of diet-induced metabolic stress and AD as well as the therapeutic potential of chia
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bb9f5b748f3b8318acde04ae3839617
https://doi.org/10.1038/s41598-020-75209-z
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