Magnetic Resonance Imaging Tissue Signatures Associated With White Matter Changes Due to Sporadic Cerebral Small Vessel Disease Indicate That White Matter Hyperintensities Can Regress

Autor: Angela C. C. Jochems, Susana Muñoz Maniega, Una Clancy, Carmen Arteaga, Daniela Jaime Garcia, Francesca M. Chappell, Will Hewins, Rachel Locherty, Ellen V. Backhouse, Gayle Barclay, Charlotte Jardine, Donna McIntyre, Iona Gerrish, Agniete Kampaite, Eleni Sakka, Maria Valdés Hernández, Stewart Wiseman, Mark E. Bastin, Michael S. Stringer, Michael J. Thrippleton, Fergus N. Doubal, Joanna M. Wardlaw

Publikováno v: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 3 (2024)

Background White matter hyperintensities (WMHs) might regress and progress contemporaneously, but we know little about underlying mechanisms. We examined WMH change and underlying quantitative magnetic resonance imaging tissue measures over 1 year in

Externí odkaz: https://doaj.org/article/dcfe426c30cb4135a01b525bb04196f4

Relationship between inferior frontal sulcal hyperintensities on brain MRI, ageing and cerebral small vessel disease

Autor: Madeleine Murphy, Iona Hamilton, Joanna M. Wardlaw, Hwee Fang Lim, Jun-fang Zhang, Lucy Kesseler, Simon R. Cox, Will Hewins, Michael S. Stringer, Gayle Barclay, Yun-cheng Wu, Carol Di Perri, Francesca M Chappell, Una Clancy, Stewart Wiseman, Susana Muñoz Maniega, Fergus N. Doubal, Maria del C. Valdés-Hernández, Charlotte Jardine, Donna McIntyre, Mark E. Bastin, Michael J. Thrippleton, Daniela Jaime Garcia

Publikováno v: Zhang, J, Lim, H F, Chappell, F M, Clancy, U, Wiseman, S, Valdés-hernández, M C, Garcia, D J, Bastin, M E, Doubal, F N, Hewins, W, Cox, S R, Maniega, S M, Thrippleton, M, Stringer, M, Jardine, C, Mcintyre, D, Barclay, G, Hamilton, I, Kesseler, L, Murphy, M, Perri, C D, Wu, Y & Wardlaw, J M 2021, ' Relationship between inferior frontal sulcal hyperintensities on brain MRI, ageing and cerebral small vessel disease ', Neurobiology of Aging, vol. 106, pp. 130-138 . https://doi.org/10.1016/j.neurobiolaging.2021.06.013

Raised signal in cerebrospinal fluid (CSF) on fluid-attenuated inversion recovery (FLAIR) may indicate raised CSF protein or debris and is seen in inferior frontal sulci on routine MRI. To explore its clinical relevance, we assessed the association o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc3ee7e7504f9c142556fca84193b781
https://hdl.handle.net/20.500.11820/06961714-3d2e-4574-9935-80e0ed4939b1