Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Charlotte Hetzel"'
Publikováno v:
Clinical Immunology and Immunopathology. 80:S23-S30
Allergic inflammatory responses are regulated by cytokines [interleukin (IL)-4, IL-5, IL-10, and IL-13] produced by CD4+ helper (Th0and Th2) cells. The activation of these T cells follows engagement of T-cell antigen receptors (TCR) by antigenic pept
Autor:
Charlotte Hetzel, Jonathan B. Cooper, Nanna M. Kristensen, Riny Janssen, Jonathan R. Lamb, Douglas B. Young, Sarah J. Ely, Karen Bunting, J.E.R. Thole
We have developed a novel epitope delivery system based on the insertion of peptides within a permissive loop of a bacterial superoxide dismutase molecule. This system allowed high-level expression of heterologous peptides in two mycobacterial vaccin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4edac7d8941d0639613227209ed7b67a
https://europepmc.org/articles/PMC108397/
https://europepmc.org/articles/PMC108397/
Publikováno v:
Biochemical Society transactions. 25(2)
Autor:
Charlotte Hetzel, John D. Hayball, Nanna M. Kristensen, J. R. Lamb, Timothy Bourne, Gerard F. Hoyne
Publikováno v:
International immunology. 8(7)
In this study we demonstrate that immunization of H-2(b) mice with the allergen Der p 1 induces MHC class II restricted T cells that proliferate to residues 15-29 of Der p 1 (p15-29) and to the murine MHC class II-associated invariant chain derived p
Publikováno v:
International immunology. 8(3)
We have previously demonstrated that intranasal (i.n.) administration of an immunodominant peptide (p1-111-139) derived from the house dust mite (HDM) allergen Der p 1 inhibits antigen-specific CD4+ T cell responses in H-2b mice. Here we report that
Autor:
Nanna M. Kristensen, Jonathan Robert Lamb, Charlotte Hetzel, Gerard F. Hoyne, D. C. Tsitoura, Timothy Bourne
Publikováno v:
MHC Molecules: Expression, Assembly and Function ISBN: 9781468464641
Allergic disorders such as asthma and atopic dermatitis are the result of inappropriate immune responses to environmental allergens, particularly those derived from house dust mites, pollens, animal dander, fungal spores, insect venom and certain foo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4c765c2a8b871860f44bea4d8d402f62
https://doi.org/10.1007/978-1-4684-6462-7_16
https://doi.org/10.1007/978-1-4684-6462-7_16
Autor:
Jonathan R. Lamb, Charlotte Hetzel
Publikováno v:
Clinical immunology and immunopathology. 73(1)
In recent years there have been considerable advances in our knowledge of the cellular and molecular events following ligation of the T cell receptor. The quantitative and qualitative characteristics of the signal(s) received by a naive or memory T c
Publikováno v:
Immunology Letters. 56:218-219
Publikováno v:
Scopus-Elsevier
Quantitative and qualitative characteristics of the signals received by a T cell determine whether receptor ligation results in cell activation, cell death, or the induction of antigen-specific non-responsiveness. Environmental factors such as the na
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0733a8a4092d2e27a169dba9d3325fa7
http://www.scopus.com/inward/record.url?eid=2-s2.0-0028998854&partnerID=MN8TOARS
http://www.scopus.com/inward/record.url?eid=2-s2.0-0028998854&partnerID=MN8TOARS