Výsledky vyhledávání - "Charlotte Gruber"

Abstract P5-13-33: Longitudinal transcriptional profiling of CTCs in metastatic breast cancer patients receiving the CDK4/6 inhibitor Palbociclib to predict therapy response

Autor: Sabine Kasimir-Bauer, Charlotte Gruber, Oliver Hoffmann, Rainer Kimmig, Corinna Keup

Publikováno v: Cancer Research. 82:P5-13

Background: CDK4/6 inhibitors represent a new treatment option for metastatic (M), hormone receptor-positive/HER2-negative (HR+/HER2-) breast cancer (BC) patients. However, predictive markers have not been defined to decide who will benefit from CDK4

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a413990438dcc6893dad3f94daf1db42
https://doi.org/10.1158/1538-7445.sabcs21-p5-13-33

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Abstract 2140: DNA damage response in circulating tumor cells shows predictive value for metastatic breast cancer patients receiving CDK4/6 inhibitors

Autor: Corinna Keup, Charlotte Gruber, Stefanos Ioannis Moukas, Mitra Tewes, Hans-Christian Kolberg, Rainer Kimmig, Sabine Kasimir-Bauer

Publikováno v: Cancer Research. 83:2140-2140

Background: Resistance to CDK4/6 inhibitors (CDK4/6i), like Palbociclib and Ribociclib, plus endocrine therapy (TX) is an omnipresent topic for metastatic (M), hormone receptor-positive/HER2-negative (HR+/HER2-) breast cancer (BC) patients (pts). Cir

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::44db93243887351d86a1efddd89200b8
https://doi.org/10.1158/1538-7445.am2023-2140

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Abstract P5-02-25: Transcriptional profiling of CTCs in metastatic breast cancer patients in the course of CDK4/6 inhibition

Autor: Sabine Kasimir-Bauer, Charlotte Gruber, Stefanos Moukas, Mitra Tewes, Hans-Christian Kolberg, Rainer Kimmig, Corinna Keup

Publikováno v: Cancer Research. 83:P5-02

Background: De novo resistance defined as progression within six months and acquired resistance are one of the major problems in the subset of metastatic (M), hormone receptor-positive/HER2-negative (HR+/HER2-) breast cancer (BC) patients without vis

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0d1ae98ff6fba0725f36410fa47142e8
https://doi.org/10.1158/1538-7445.sabcs22-p5-02-25

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Abstract 6256: Longitudinal transcriptional profiling of CTCs in metastatic breast cancer patients receiving CDK4/6 inhibitors to predict response

Autor: Corinna Keup, Charlotte Gruber, Oliver Hoffmann, Rainer Kimmig, Sabine Kasimir-Bauer

Publikováno v: Cancer Research. 82:6256-6256

Background: CDK4/6 inhibitors recently became the first choice for treatment of metastatic (M), hormone receptor-positive/HER2-negative (HR+/HER2-) breast cancer (BC) patients (pts). However, predictive markers are missing. Circulating tumor cells (C

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5377f296e672ce7b550d6b2119a23cfe
https://doi.org/10.1158/1538-7445.am2022-6256

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Elektronická kniha

Occupy Antigone : Tradition, Transition and Transformation in Performance

Autor: Katharina Pewny, Luc Van den Dries, Charlotte Gruber, Simon Leenknegt

This anthology provides some of today's most relevant views on Sophocles'classic and its many interpretations from an interdisciplinary, cross-cultural perspective. It critically investigates the work of artists and theoreticians who have occupied An

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Elektronická kniha

InterActions : Performing Actual and Virtual Spaces As Stages of Inter-est

Autor: Charlotte Gruber, Kati Röttger, Katharina Pewny

What do famous 20th century thinkers like Hannah Arendt, Guy Debord and Henri Lefebvre have to offer for a critical performance analysis today? Charlotte Gruber has taken a fresh look at their writings with respect to this question. In'InterActions's

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The tyrosine kinase Lck is involved in regulation of mitochondrial apoptosis pathways

Autor: Wilfried Budach, Claus Belka, Sebastian Wesselborg, Charlotte Gruber, Verena Jendrossek

Publikováno v: Oncogene. 22:176-185

The induction of apoptosis requires the activation of a highly coordinated signaling network ultimately leading to the activation of caspases. In previous experiments we and others have shown that the tyrosine kinase Lck is required for adequate apop

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71e9a83de933258a039ae932b55e5e38
https://doi.org/10.1038/sj.onc.1206103

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Scenography of virtual sound-stages

Autor: Charlotte Gruber

Publikováno v: PERFORMANCE RESEARCH

What happens to the weight of a voice, to the actualization of agency in a world accompanied by the World Wide Web? Is the internet just an interactive archive, which oscillates between real-time s...

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d454fdf3f49cfe4d5d11d02351b3414
https://hdl.handle.net/1854/LU-6847381

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Proapoptotic activity of Ukrain is based on Chelidonium majus L. alkaloids and mediated via a mitochondrial death pathway

Autor: Michael Bamberg, Verena Jendrossek, Nils Cordes, Bernd Kammerer, René Handrick, Claus Belka, Peter T. Daniel, Daniel Habermehl, Therese Eldh, Charlotte Gruber, Ludwig Plasswilm

Publikováno v: BMC Cancer
Scopus-Elsevier
BMC Cancer 6: 14.
BMC Cancer, Vol 6, Iss 1, p 14 (2006)

BackgroundThe anticancer drug Ukrain (NSC-631570) which has been specified by the manufacturer as semisynthetic derivative of theChelidonium majusL. alkaloid chelidonine and the alkylans thiotepa was reported to exert selective cytotoxic effects on h

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a9047db24cdd1d7dab0c6d7b41e562f
https://pubmed.ncbi.nlm.nih.gov/16417634

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