Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Charlotte Girard‐Guyonvarc'h"'
Autor:
Elien Eeckhout, Tomoko Asaoka, Hanne Van Gorp, Dieter Demon, Charlotte Girard-Guyonvarc’h, Vanessa Andries, Lars Vereecke, Cem Gabay, Mohamed Lamkanfi, Geert van Loo, Andy Wullaert
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundAutoinflammation with infantile enterocolitis (AIFEC) is an often fatal disease caused by gain-of-function mutations in the NLRC4 inflammasome. This inflammasomopathy is characterized by macrophage activation syndrome (MAS)-like episodes as
Externí odkaz:
https://doaj.org/article/22257ef24119463f84ae7fbc3bf11db2
Autor:
Sebastien Fauteux-Daniel, Laura M. Merlo Pich, Charlotte Girard-Guyonvarc’h, Assunta Caruso, Emiliana Rodriguez, Cem Gabay
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundInterleukin-18 is a proinflammatory cytokine, the activity of which is regulated by its natural inhibitor, IL-18 binding protein (IL-18BP). Elevated circulating levels of IL-18 have been observed in patients with systemic juvenile idiopathi
Externí odkaz:
https://doaj.org/article/4a6d6914ddc34728996710f63811959e
Publikováno v:
Journal of Immunology, Vol. 205, No 4 (2020) pp. 1167-1175
IL-18 binding protein (IL-18BP) acts as a naturally occurring IL-18 decoy receptor. If the balance between IL-18 and IL-18BP is dysregulated, abnormal levels of free bioactive IL-18 are detected, such as in the sera of Il-18bp knockout (KO) mice with
Publikováno v:
Revue Médicale Suisse. 16:487-491
Publikováno v:
Journal of Clinical Medicine, Vol 11, Iss 430, p 430 (2022)
Journal of Clinical Medicine
Journal of Clinical Medicine
Interleukin 18 (IL-18) is a pro-inflammatory cytokine of the IL-1 family, whose activity is tightly controlled at the level of production, as well as signalization. Notably, it is buffered by its natural inhibitor, IL-18 binding protein (IL-18BP), wh
Publikováno v:
Cytokine. 150
Interleukin (IL)-18 is a member of the IL-1 family of cytokines with pleiotropic and potent pro-inflammatory activities that are tightly controlled at the level of production and in the extracellular space. Indeed, IL-18 is translated as a leaderless
Autor:
Christoph Kessel, Richard Vollenberg, Katja Masjosthusmann, Claas Hinze, Helmut Wittkowski, France Debaugnies, Carole Nagant, Francis Corazza, Frédéric Vély, Gilles Kaplanski, Charlotte Girard‐Guyonvarc’h, Cem Gabay, Hartmut Schmidt, Dirk Foell, Phil‐Robin Tepasse
Publikováno v:
Arthritis & rheumatology
Arthritis & rheumatology, Wiley, 2021, 73 (10), pp.1791-1799. ⟨10.1002/art.41763⟩
Arthritis & Rheumatology
Arthritis and Rheumatology, Vol. 73, No 10 (2021) pp. 1791-1799
Arthritis & Rheumatology (Hoboken, N.j.)
Arthritis & rheumatology, 2021, 73 (10), pp.1791-1799. ⟨10.1002/art.41763⟩
Arthritis & rheumatology, Wiley, 2021, 73 (10), pp.1791-1799. ⟨10.1002/art.41763⟩
Arthritis & Rheumatology
Arthritis and Rheumatology, Vol. 73, No 10 (2021) pp. 1791-1799
Arthritis & Rheumatology (Hoboken, N.j.)
Arthritis & rheumatology, 2021, 73 (10), pp.1791-1799. ⟨10.1002/art.41763⟩
Infection with the novel coronavirus SARS-CoV-2 triggers severe illness with high mortality in a subgroup of patients. Such a critical course of COVID-19 is thought to be associated with the development of cytokine storm, a condition seen in macropha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3895043e58ded4b2d22a6fa71399646
https://hal-amu.archives-ouvertes.fr/hal-03374533
https://hal-amu.archives-ouvertes.fr/hal-03374533
Autor:
Adriana de Jesus, Daniel L. Kastner, Charlotte Girard-Guyonvarc'h, Scott W. Canna, Wonyong Lee, Amanda K. Ombrello, Corinne Schneider, Jae Jin Chae, Ivona Aksentijevich, Juan I. Aróstegui, Raphaela Goldbach-Mansky, Cem Gabay, Vinh Dang, Deborah L. Stone
Publikováno v:
Arthritis Rheumatol
Dominantly inherited PSTPIP1 mutations cause a spectrum of autoinflammatory manifestations epitomized by PAPA syndrome (pyogenic sterile arthritis, pyoderma gangrenosum, and acne (PAPA) syndrome.). The connections between PSTPIP1 and PAPA syndrome ar
Autor:
Ndate Fall, Rachel A. Brown, Cem Gabay, Scott W. Canna, Grant S. Schulert, Shima Yasin, Alexei A. Grom, Maggie Henderlight, Charlotte Girard-Guyonvarc'h
Publikováno v:
Rheumatology (Oxford)
Rheumatology, Vol. 59, No 2 (2020) pp. 361-366
Rheumatology, Vol. 59, No 2 (2020) pp. 361-366
Objectives Systemic juvenile idiopathic arthritis (sJIA) is a childhood arthritis with features of autoinflammation and high risk of macrophage activation syndrome (MAS). IL-18 has been shown to have key roles in sJIA and MAS. We aimed to examine IL-
Autor:
Scott W. Canna, Daniel L. Kastner, Corinne Schneider, Wonyong Lee, Juan I. Aróstegui, Jae Jin Chae, Adriana de Jesus, Charlotte Girard-Guyonvarc'h, Raphaela Goldbach-Mansky, Amanda K. Ombrello, Ivona Aksentijevich, Deborah L. Stone, Cem Gabay
ObjectiveDominantly-inherited mutations in PSTPIP1 cause a family of monogenic autoinflammatory diseases epitomized by Pyogenic Arthritis, Pyoderma gangrenosum, and Acne (PAPA) syndrome. The connections between PSTPIP1 and PAPA are poorly understood,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::04e90a5ce17cdb8ddfe30487fd349c71
https://doi.org/10.1101/2021.02.22.21251857
https://doi.org/10.1101/2021.02.22.21251857