Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Charlotte Gineste"'
Autor:
Charlotte Gineste, Sonia Youhanna, Sabine U. Vorrink, Sara Henriksson, Andrés Hernández, Arthur J. Cheng, Thomas Chaillou, Andreas Buttgereit, Dominik Schneidereit, Oliver Friedrich, Kjell Hultenby, Joseph D. Bruton, Niklas Ivarsson, Linda Sandblad, Volker M. Lauschke, Håkan Westerblad
Publikováno v:
iScience, Vol 25, Iss 12, Pp 105654- (2022)
Summary: Cells rapidly lose their physiological phenotype upon disruption of their extracellular matrix (ECM)-intracellular cytoskeleton interactions. By comparing adult mouse skeletal muscle fibers, isolated either by mechanical dissection or by col
Externí odkaz:
https://doaj.org/article/28a20786507944e29cd08fe6371fe36e
Autor:
Benjamin Chatel, Sylvie Ducreux, Zeina Harhous, Nadia Bendridi, Isabelle Varlet, Augustin C. Ogier, Monique Bernard, Julien Gondin, Jennifer Rieusset, Håkan Westerblad, David Bendahan, Charlotte Gineste
Publikováno v:
Disease Models & Mechanisms, Vol 14, Iss 9 (2021)
Mitochondrial diseases are genetic disorders that lead to impaired mitochondrial function, resulting in exercise intolerance and muscle weakness. In patients, muscle fatigue due to defects in mitochondrial oxidative capacities commonly precedes muscl
Externí odkaz:
https://doaj.org/article/1d6c38b12e5640108ab99eb5d7016953
Autor:
Charlotte Gineste, Coen Ottenheijm, Yann Le Fur, Sébastien Banzet, Emilie Pecchi, Christophe Vilmen, Patrick J Cozzone, Nathalie Koulmann, Edna C Hardeman, David Bendahan, Julien Gondin
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e109066 (2014)
Nemaline myopathy is the most common disease entity among non-dystrophic skeletal muscle congenital diseases. The first disease causing mutation (Met9Arg) was identified in the gene encoding α-tropomyosin slow gene (TPM3). Considering the conflictin
Externí odkaz:
https://doaj.org/article/b32b4c15c7ce415da68396d55d8cb58a
Autor:
Charlotte Gineste, Yann Le Fur, Christophe Vilmen, Arnaud Le Troter, Emilie Pecchi, Patrick J Cozzone, Edna C Hardeman, David Bendahan, Julien Gondin
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e61517 (2013)
Nemaline myopathy (NM) is the most common disease entity among non-dystrophic skeletal muscle congenital diseases. Mutations in the skeletal muscle α-actin gene (ACTA1) account for ∼25% of all NM cases and are the most frequent cause of severe for
Externí odkaz:
https://doaj.org/article/15dfb273180c41c6a596155050b68a20
Autor:
Charlotte Gineste, Guillaume Duhamel, Yann Le Fur, Christophe Vilmen, Patrick J Cozzone, Kristen J Nowak, David Bendahan, Julien Gondin
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e72294 (2013)
Nemaline myopathy (NM), the most common non-dystrophic congenital disease of skeletal muscle, can be caused by mutations in the skeletal muscle α-actin gene (ACTA1) (~25% of all NM cases and up to 50% of severe forms of NM). Muscle function of the r
Externí odkaz:
https://doaj.org/article/adbb7b1661c64ab388f04b42da99d788
Publikováno v:
Brain.
Congenital myopathies define a genetically heterogeneous group of disorders associated with severe muscle weakness, for which no therapies are currently available. Here we investigated the repurposing of tamoxifen in mouse models of mild or severe fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e1f89aa3feebaabac60f88eebe3eb06
https://doi.org/10.1093/brain/awac489
https://doi.org/10.1093/brain/awac489
Autor:
Benjamin Chatel, Isabelle Varlet, Augustin C. Ogier, Emilie Pecchi, Monique Bernard, Julien Gondin, Håkan Westerblad, David Bendahan, Charlotte Gineste
Mitochondrial myopathies are rare genetic disorders characterized by muscle weakness and exercise intolerance. Currently, no effective treatment exists for these myopathies. Interestingly, the pharmacological cyclophilin inhibitor cyclosporine A (CsA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::25cc53ce9fa2488bfe75ae1e5c49a8ef
https://doi.org/10.1101/2022.10.14.511701
https://doi.org/10.1101/2022.10.14.511701
Autor:
Charlotte Gineste, Jocelyn Laporte
Publikováno v:
Current opinion in pharmacology. 68
Congenital myopathies are rare and severe genetic diseases affecting the skeletal muscle function in children and adults. They present a variable spectrum of phenotypes and a genetic heterogeneity. Subgroups are defined according to the clinical and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4488d3cc6bb1374825d1d488908b1b8
https://pubmed.ncbi.nlm.nih.gov/36512981
https://pubmed.ncbi.nlm.nih.gov/36512981
Autor:
Swamynathan, Manojit M., Kuang, Shan, Watrud, Kaitlin E., Doherty, Mary R., Mathew, Charlotte Gineste Grinu, Gong, Grace Q., Cox, Hilary, Cheng, Eileen, Reiss, David, Kendall, Jude, Ghosh, Diya, Reczek, Colleen R., Zhao, Xiang, Herzka, Tali, Špokaitė, Saulė, Dessus, Antoine N., Kim, Seung Tea, Klingbeil, Olaf, Liu, Juan, Nowak, Dawid G.
Publikováno v:
Science; 10/25/2024, Vol. 386 Issue 6720, p399-399, 1p, 1 Color Photograph
Autor:
Thomas Chaillou, Kjell Hultenby, Sonia Youhanna, Sabine U. Vorrink, Arthur J. Cheng, Oliver Friedrich, Andrés Hernández, Joseph D. Bruton, Volker M. Lauschke, Linda Sandblad, Sara Henriksson, Håkan Westerblad, Dominik Schneidereit, Andreas Buttgereit, Charlotte Gineste, Niklas Ivarsson
SummaryCells rapidly lose their physiological phenotype upon disruption of their extracellular matrix (ECM)-intracellular cytoskeleton interactions. Here, we investigated acute effects of ECM disruption on cellular and mitochondrial morphology, trans
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3a5dc2ad18292d945e196e4e6ab78f4b
https://doi.org/10.1101/2021.03.29.437546
https://doi.org/10.1101/2021.03.29.437546