Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Charlotte Gaupp"'
Autor:
Thomas W. Johnson, James Holt, Anna Kleyman, Shengyu Zhou, Eva Sammut, Vito Domenico Bruno, Charlotte Gaupp, Giacomo Stanzani, John Martin, Pietro Arina, Julia Deutsch, Raimondo Ascione, Mervyn Singer, Alex Dyson
Publikováno v:
Redox Biology, Vol 73, Iss , Pp 103167- (2024)
Sulfide-releasing compounds reduce reperfusion injury by decreasing mitochondria-derived reactive oxygen species production. We previously characterised ammonium tetrathiomolybdate (ATTM), a clinically used copper chelator, as a sulfide donor in rode
Externí odkaz:
https://doaj.org/article/82bfc60840f64f74b4aa5411b2d5d7c0
Autor:
Charlotte Gaupp, Benjamin Schmid, Philipp Tripal, Aurélie Edwards, Christoph Daniel, Stefan Zimmermann, Margarete Goppelt-Struebe, Carsten Willam, Seymour Rosen, Gunnar Schley
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-15 (2023)
Abstract Functional and structural alterations of peritubular capillaries (PTCs) are a major determinant of chronic kidney disease (CKD). Using a software-based algorithm for semiautomatic segmentation and morphometric quantification, this study anal
Externí odkaz:
https://doaj.org/article/d556644488c64dfabdd56ca82c5dd2ca
Autor:
Vera B. M. Peters, Nishkantha Arulkumaran, Miranda J. Melis, Charlotte Gaupp, Thierry Roger, Manu Shankar-Hari, Mervyn Singer
Publikováno v:
Life, Vol 12, Iss 12, p 2034 (2022)
Mitochondrial dysfunction and immune cell dysfunction are commonplace in sepsis and are associated with increased mortality risk. The short chain fatty acid, butyrate, is known to have anti-inflammatory effects and promote mitochondrial biogenesis. W
Externí odkaz:
https://doaj.org/article/aa72f13338ef45159e0ae8e75a4ed06c
Autor:
Vera B.M. Peters, Robert Tidswell, Timothy A C Snow, Giacomo Stanzani, Mervyn Singer, Charlotte Gaupp, Michael R. Duchen, Nishkantha Arulkumaran, Sean Pollen
Publikováno v:
British Journal of Anaesthesia. 127:577-586
Excess mitochondrial reactive oxygen species (mROS) in sepsis is associated with organ failure, in part by generating inflammation through the NOD-, LRR- and pyrin domain-containing protein 3 (NLRP3) inflammasome. We determined the impact of a mitoch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce764a9efcafd61f7a5dce763bf14887
https://doi.org/10.1016/j.bja.2021.05.036
https://doi.org/10.1016/j.bja.2021.05.036
Autor:
Mervyn Singer, Charlotte Gaupp, Conor Lanphere, Stefan Howorka, Nishkantha Arulkumaran, Jonathan R. Burns
Publikováno v:
ACS Nano. 15:4394-4404
DNA nanotechnology produces precision nanostructures of defined chemistry. Expanding their use in biomedicine requires designed biomolecular interaction and function. Of topical interest are DNA nanostructures that function as vaccines with potential
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::742bd3a804a70cbd07421bdfe3f5d2fc
https://doi.org/10.1021/acsnano.0c07915
https://doi.org/10.1021/acsnano.0c07915