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pro vyhledávání: '"Charlotte Ehle"'
Downregulation of HNF4A enables transcriptomic reprogramming during the hepatic acute-phase response
Autor:
Charlotte Ehle, Aishwarya Iyer-Bierhoff, Yunchen Wu, Shaojun Xing, Michael Kiehntopf, Alexander S. Mosig, Maren Godmann, Thorsten Heinzel
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-14 (2024)
Abstract The hepatic acute-phase response is characterized by a massive upregulation of serum proteins, such as haptoglobin and serum amyloid A, at the expense of liver homeostatic functions. Although the transcription factor hepatocyte nuclear facto
Externí odkaz:
https://doaj.org/article/d64b52140413424a88288fcc89daade1
Autor:
Yunchen Wu, Yudan He, Chen Liu, Charlotte Ehle, Aishwarya Iyer-Bierhoff, Bing Liu, Thorsten Heinzel, Shaojun Xing
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 15, p 12448 (2023)
Sepsis is a life-threatening medical emergency triggered by excessive inflammation in response to an infection. High mortality rates and limited therapeutic options pose significant challenges in sepsis treatment. Histone deacetylase inhibitors (HDAC
Externí odkaz:
https://doaj.org/article/aa14d8cea81d4609bb83b88d5f91bee3