Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Charlotte E. Flanagan"'
Autor:
Adam J. Dobson, Marina Ezcurra, Charlotte E. Flanagan, Adam C. Summerfield, Matthew D.W. Piper, David Gems, Nazif Alic
Publikováno v:
Cell Reports, Vol 18, Iss 2, Pp 299-306 (2017)
Summary: Consumption of unhealthy diets is exacerbating the burden of age-related ill health in aging populations. Such diets can program mammalian physiology to cause long-term, detrimental effects. Here, we show that, in Drosophila melanogaster, an
Externí odkaz:
https://doaj.org/article/2f8034f5e50b4e5f8f5dded8d9438fba
Autor:
Maria Demontis, Silvia A. Ferreira, Rosie M. Butler, Christine L. Jones, Tracey J. Mitchell, Isabella Tosi, Charlotte E. Flanagan, Robert C.T. McKenzie, Wesley J. Woollard, Sean Whittaker, Susan D. John
Publikováno v:
Butler, R M, Mckenzie, R C, Jones, C L, Flanagan, C E, Woollard, W J, Demontis, M, Ferreira, S, Tosi, I, John, S, Whittaker, S J & Mitchell, T J 2019, ' Contribution of STAT3 and RAD23B in Primary Sézary Cells to Histone Deacetylase Inhibitor FK228 Resistance ', Journal of Investigative Dermatology, vol. 139, no. 9, pp. 1975-1984.e2 . https://doi.org/10.1016/j.jid.2019.03.1130
FK228 (romidepsin) and suberoylanilide hydroxamic acid (vorinostat) are histone deacetylase inhibitors (HDACi) approved by the US Food and Drug Administration for cutaneous T-cell lymphoma (CTCL), including the leukemic subtype Sezary syndrome. This
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c639eeccf4bbbe400c2de80d80080b01
https://kclpure.kcl.ac.uk/ws/files/110043202/PIIS0022202X19313405.pdf
https://kclpure.kcl.ac.uk/ws/files/110043202/PIIS0022202X19313405.pdf
Autor:
Farrah S. Bakr, Antoinette Yoxall, Varsha M. Patel, Nelema Begum, Charlotte E. Flanagan, Matilda Katan, Christine L. Jones, Sean Whittaker, Rosie M. Butler, Tracey J. Mitchell, Marta Martins, Wesley J. Woollard
Publikováno v:
The Journal of investigative dermatology. 140(2)
Phospholipase C Gamma 1 (PLCG1) is frequently mutated in primary cutaneous T-cell lymphoma (CTCL). This study functionally interrogated nine PLCG1 mutations (p.R48W, p.S312L, p.D342N, p.S345F, p.S520F, p.R1158H, p.E1163K, p.D1165H, and the in-frame i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fb6020fe73281ee9084bf5ee9ebccda
https://pubmed.ncbi.nlm.nih.gov/31376383
https://pubmed.ncbi.nlm.nih.gov/31376383
Autor:
Adam J, Dobson, Marina, Ezcurra, Charlotte E, Flanagan, Adam C, Summerfield, Matthew D W, Piper, David, Gems, Nazif, Alic
Publikováno v:
Cell Reports
Summary Consumption of unhealthy diets is exacerbating the burden of age-related ill health in aging populations. Such diets can program mammalian physiology to cause long-term, detrimental effects. Here, we show that, in Drosophila melanogaster, an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::86b811032d10792c4c1235703bc0fa09
https://pubmed.ncbi.nlm.nih.gov/28076775
https://pubmed.ncbi.nlm.nih.gov/28076775
Autor:
Anna Lorenc, Joshua Fisher, Varsha M. Patel, Rebecca Tarrant, Nubia Castillo-Mosquera, Elisabeth A. Nuttall, Carl Z. Beyers, Michael A. Simpson, Sean Whittaker, Silvia Aguilar-Duran, Kiran Dedhia, Ceri A. Roberts, Nelema Begum, Farrah S. Bakr, Isabella Tosi, Tracey J. Mitchell, Ricarda M. Hoffmann, Aria A. Ghasemi, Silvia Ferreira, Venu Pullabhatla, Emmanouil G Solomonidis, Rosie M. Butler, Anthony Bayega, Emanuele de Rinaldis, Wesley J. Woollard, Arisa Paul, Charlotte E. Flanagan, Antoinette Yoxall
Publikováno v:
Blood. 127(26)
Sezary syndrome (SS) is a leukemic variant of cutaneous T-cell lymphoma (CTCL) and represents an ideal model for study of T-cell transformation. We describe whole-exome and single-nucleotide polymorphism array–based copy number analyses of CD4+ tum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e9531a1f301d8633f688c2a0d6f3bbe
https://pubmed.ncbi.nlm.nih.gov/27121473
https://pubmed.ncbi.nlm.nih.gov/27121473
Publikováno v:
European Journal of Cancer. 101:S14
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f889500a4070b7f5a5b536b26adbd52e
https://doi.org/10.1016/j.ejca.2018.07.179
https://doi.org/10.1016/j.ejca.2018.07.179