Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Charlotte E. Carver"'
Autor:
Emma J. Jones, Charles S. Lay, Charlotte E. Carver, John P. Evans, Kristopher McCombe, Alexander N Phillipou, Daniel Thomas, Peter D. Craggs, Cassie Messenger, Mahnoor Mahmood, Kelly M Gatfield, Kristin M. Riching, Laurie J. Gordon, Matthew Campbell
Publikováno v:
Cell chemical biology. 29(2)
Contemporary drug discovery typically quantifies the effect of a molecule on a biological target using the equilibrium-derived measurements of IC50, EC50, or KD. Kinetic descriptors of drug binding are frequently linked with the effectiveness of a mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90084736e1ff6bc1f295e0de7992c456
https://pubmed.ncbi.nlm.nih.gov/34520747
https://pubmed.ncbi.nlm.nih.gov/34520747
Autor:
Cassie Messenger, Laurie J. Gordon, Simon C. C. Lucas, Aaron T. Cheng, Kelly M Gatfield, John P. Evans, Emma J. Jones, Mahnoor Mahmood, Charles S. Lay, Charlotte E. Carver, Douglas Sammon, Antonia J. Lewis, Alexander N Phillipou, Syandan Chakraborty, Luke A Greenhough, Peter D. Craggs, David J Brierley
Publikováno v:
SLAS discovery : advancing life sciences RD. 25(2)
Malfunctions in the basic epigenetic mechanisms such as histone modifications, DNA methylation, and chromatin remodeling are implicated in a number of cancers and immunological and neurodegenerative conditions. Within GlaxoSmithKline (GSK) we have ut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc63556b946b71c8a1576c30413bb503
https://pubmed.ncbi.nlm.nih.gov/31875412
https://pubmed.ncbi.nlm.nih.gov/31875412