Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Charlotte E Rutledge"'
Autor:
Charlotte E Rutledge, Ho-Tak Lau, Hazel Mangan, Linda L Hardy, Olaf Sunnotel, Fan Guo, Angus M MacNicol, Colum P Walsh, Diane J Lees-Murdock
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e88385 (2014)
Regulation of DNMT1 is critical for epigenetic control of many genes and for genome stability. Using phylogenetic analysis we characterized a block of 27 nucleotides in the 3'UTR of Dnmt1 mRNA identical between humans and Xenopus and investigated the
Externí odkaz:
https://doaj.org/article/ded1e919582a401c89d9eaa7a96e6861
Autor:
John A. Halsall, Simon Andrews, Felix Krueger, Charlotte E. Rutledge, Gabriella Ficz, Wolf Reik, Bryan M. Turner
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-19 (2021)
Abstract Chromatin configuration influences gene expression in eukaryotes at multiple levels, from individual nucleosomes to chromatin domains several Mb long. Post-translational modifications (PTM) of core histones seem to be involved in chromatin s
Externí odkaz:
https://doaj.org/article/638296035c4644d5b4cc65f25c7d7cda
Publikováno v:
Journal of Experimental Biology. 226
Journal of Experimental Biology was launched in 1923 as The British Journal of Experimental Biology, with a single issue being published in the October of that year. As we celebrate our centenary, we look back at that first issue and the zoologists p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::77eed140d9b6a87c64d3786e7dab41e9
https://doi.org/10.1242/jeb.245424
https://doi.org/10.1242/jeb.245424
Autor:
Charlotte E. Rutledge, Bryan M. Turner, Wolf Reik, John A. Halsall, Gabriella Ficz, Felix Krueger, Simon Andrews
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-19 (2021)
Scientific Reports
Scientific Reports
Chromatin configuration influences gene expression in eukaryotes at multiple levels, from individual nucleosomes to chromatin domains several Mb long. Post-translational modifications (PTM) of core histones seem to be involved in chromatin structural
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2dd1bc6553885059fc83f90db074e7c
Autor:
Gabriella Ficz, Bryan M. Turner, Wolf Reik, Charlotte E. Rutledge, Felix Krueger, John A. Halsall, Simon Andrews
BackgroundChromatin configuration influences gene expression in eukaryotes at multiple levels, from individual nucleosomes to chromatin domains several Mb long. Post-translational modifications (PTM) of core histones seem to be involved in chromatin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a7080115b12b609261e6e53c0ee81765
https://doi.org/10.1101/2020.10.16.341446
https://doi.org/10.1101/2020.10.16.341446
Autor:
Kenichiro Hata, Shun Sato, Colum P. Walsh, Charlotte E. Rutledge, Diane J. Lees-Murdock, Alan M. O'Doherty, Avinash Thakur
Publikováno v:
Developmental Biology. 356:411-420
The DNA methyltransferase 3-like (Dnmt3L) protein is a crucial cofactor in the germ line for the de novo methyltransferase Dnmt3a, which establishes imprints and represses transposable elements. We have previously shown that Dnmt3L transcription is r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e406e406f5f258b62ae58e573cd529e
https://doi.org/10.1016/j.ydbio.2011.05.665
https://doi.org/10.1016/j.ydbio.2011.05.665
Autor:
Charlotte E. Rutledge, Bryan M. Turner
Publikováno v:
Epigenetics for Drug Discovery ISBN: 9781849738828
The genetic material of nearly all eukaryotes is maintained in the nucleus in the form of chromatin, which consists of DNA wrapped around histone proteins. The histone proteins have the potential to undergo an impressive variety of post-translational
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d8316520de4eae426634aaddefd213d1
https://doi.org/10.1039/9781782628484-00020
https://doi.org/10.1039/9781782628484-00020
Autor:
Avinash Thakur, Rachelle E Irwin, Shun Sato, Karla O'Neill, Colum P. Walsh, Ken Hata, Charlotte E. Rutledge
Publikováno v:
Development (Cambridge, England)
A functional role for DNA methylation has been well-established at imprinted loci, which inherit methylation uniparentally, most commonly from the mother via the oocyte. Many CpG islands not associated with imprinting also inherit methylation from th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84f0004935268345d6892a9d579e92dc
https://pubmed.ncbi.nlm.nih.gov/24523459
https://pubmed.ncbi.nlm.nih.gov/24523459
Autor:
Laura P. O'Neill, Anton Wutz, Elsa Boudadi, Martin Leeb, Bryan M. Turner, Charlotte E. Rutledge, Hannah Stower, John A. Halsall, Karl P. Nightingale
Publikováno v:
Epigenetics & Chromatin, 6
Epigenetics & Chromatin
Epigenetics & Chromatin
Background Histone deacetylase inhibitors (HDACi) cause histone hyperacetylation and H3K4 hypermethylation in various cell types. They find clinical application as anti-epileptics and chemotherapeutic agents, but the pathways through which they opera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3730a1a2251e85c7751f67f5a2e92ff6
https://hdl.handle.net/20.500.11850/75442
https://hdl.handle.net/20.500.11850/75442