Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Charlotte Delaporte"'
Autor:
Judith Markovits, Jean-Marie Saucier, Françoise Chaminade, A. Jacquemin-Sablon, Sandrine Le Mée, Charlotte Delaporte
Publikováno v:
Molecular Pharmacology. 58:709-718
The new olivacine derivative S16020-2 (NSC-659687) is a DNA topoisomerase II inhibitor endowed with a remarkable antitumor activity against various experimental tumors. In vitro physicochemical properties of this compound, in particular its interacti
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression. 1264:178-182
DNA topoisomerase II beta cDNAs from Chinese hamster lung cells sensitive (DC-3F) and resistant to 9-OH-ellipticine (DC-3F/9O-HE) were isolated. In the sensitive cells, the sequence defines an open reading frame of 4839 nucleotides, and extends over
Autor:
Laurent, Gros, Charlotte, Delaporte, Stéphane, Frey, Julien, Decesse, Bruno Robert, de Saint-Vincent, Laurent, Cavarec, Anne, Dubart, Andrei V, Gudkov, Alain, Jacquemin-Sablon
Publikováno v:
Cancer research. 63(1)
Genetic suppressor elements (GSEs) are cDNA fragments encoding either truncated proteins, acting as dominant-negative mutants, or inhibitory antisense RNA segments counteracting with the gene from which they are derived. To identify genes controlling
Autor:
Alain Jacquemin-Sablon, Charlotte Delaporte, Laurent Gros, Laurent Cavarec, Stéphane Frey, Andrei V. Gudkov, D. Coccard, A. Dubar
Publikováno v:
Annals of the New York Academy of Sciences. 886
Publikováno v:
Experimental cell research. 197(2)
In the Chinese hamster lung fibroblast cell line DC-3F, the development of resistance to different drugs, through several mechanisms like MDR expression or alteration of the DNA topoisomerase II activity, has been shown to be associated with a decrea
Publikováno v:
Biochemical pharmacology. 33(22)
The effects of two 7 H -pyridocarbazole dimers, PyDi1 and PyDi2, on Chinese hamster lung cells in culture in vitro , were compared to those of the corresponding monomers, PyMo1 and PyMo2, by measuring the rates of macromolecule syntheses, the growth