Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Charlotte Dalba"'
Autor:
Charlotte Dalba, Paula M. Alves, V.M. Santiago, Ana F. Rodrigues, Miguel R. Guerreiro, Manuel J.T. Carrondo, David Klatzmann, Ana S. Coroadinha
Publikováno v:
Biotechnology and Bioengineering. 108:2623-2633
Retroviral-derived biopharmaceuticals (RV) target numerous therapeutic applications, from gene therapy to virus-like particle (rVLP)-based vaccines. During particle formation, beside the pseudotyped envelope proteins, RV can incorporate proteins deri
Publikováno v:
Molecular Therapy. 15(3):457-466
Replication-defective vectors based on murine oncoretroviruses were the first gene transfer vectors to be used in successful gene therapies. Despite this achievement, they have two major drawbacks: insufficient efficacy for in vivo gene transfer and
Publikováno v:
Current Gene Therapy. 5:655-667
As cancer gene therapy employing replication-defective vectors has met with limited clinical success, there is renewed interest in using replication-competent viruses for oncolytic virotherapy. In preclinical and clinical studies, various attenuated
Autor:
Stanley A. Plotkin, Anne-Catherine Fluckiger, David Klatzmann, Lenore Pereira, Charlotte Dalba, Barthelemy Ontsouka, Tanvir Ahmed, David E. Anderson, Marc Kirchmeier, Abebaw Diress, Jasminka Bozic, Florian Schödel, Catalina Soare
Publikováno v:
Kirchmeier, M; Fluckiger, AC; Soare, C; Bozic, J; Ontsouka, B; Ahmed, T; et al.(2014). Enveloped virus-like particle expression of human cytomegalovirus glycoprotein B antigen induces antibodies with potent and broad neutralizing activity. Clinical and Vaccine Immunology, 21(2), 174-180. doi: 10.1128/CVI.00662-13. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/73q2w2j9
Clinical and vaccine immunology : CVI, vol 21, iss 2
Clinical and vaccine immunology : CVI, vol 21, iss 2
A prophylactic vaccine to prevent the congenital transmission of human cytomegalovirus (HCMV) in newborns and to reduce life-threatening disease in immunosuppressed recipients of HCMV-infected solid organ transplants is highly desirable. Neutralizing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::263886c0ddadbf92d88d8af5b9cc8a01
http://www.escholarship.org/uc/item/73q2w2j9
http://www.escholarship.org/uc/item/73q2w2j9
Autor:
Charlotte Dalba, Mathilde Miyalou, Béhazine Combadière, David Klatzmann, Béatrice Levacher, Christophe Huret, Martin Amadoudji Zin, Olivia Bonduelle, Bertrand Bellier, Delphine Desjardins
Publikováno v:
Vaccine. 31(11)
While the immunological correlates of hepatitis C virus (HCV)-specific immunity are not well understood, it is now admitted that an effective vaccine against HCV will need to induce both cellular and humoral immune responses and address viral heterog
Autor:
Rute Castro, Miguel R. Guerreiro, Paula M. Alves, Ana F. Rodrigues, David Klatzmann, Manuel J.T. Carrondo, Charlotte Dalba, Hélio A. Tomás, Ana S. Coroadinha
Publikováno v:
BMC Proceedings
BMC Proceedings, Vol 5, Iss Suppl 8, p P72 (2011)
BMC Proceedings, Vol 5, Iss Suppl 8, p P72 (2011)
Background Retroviral based biopharmaceuticals are used in numerous therapeutic applications, from gene therapy to vaccination [1-3]. Nonetheless, retroviruses are known to incorporate proteins from the host cell which may increase the vector immunot
Autor:
Arnaud Cangialosi, Isaure Du Chene, Pia Dupeyrot-Lacas, Jimmy Mancip, Bertrand Bellier, Frédéric Tangy, Roger LeGrand, François-Loïc Cosset, Emmanuel Gauthier, David Klatzmann, Philippe E. Mangeot, Anne-Catherine Fluckiger, Isabelle Mangeot, Pierre Garrone, Charlotte Dalba, Dimitri Lavillette
Publikováno v:
Science translational medicine. 3(94)
Chronic hepatitis C virus (HCV) infection, with its cohort of life-threatening complications, affects more than 200 million persons worldwide and has a prevalence of more than 10% in certain countries. Preventive and therapeutic vaccines against HCV
Autor:
Christophe Huret, Frédéric Tangy, Charlotte Dalba, David Klatzmann, Mathilde Miyalou, Marie-Pascale Frenkiel, Delphine Desjardins, Philippe Desprès, Bertrand Bellier
Publikováno v:
Vaccine
Vaccine, Elsevier, 2009, 27 (42), pp.5772-80. ⟨10.1016/j.vaccine.2009.07.059⟩
Vaccine, 2009, 27 (42), pp.5772-80. ⟨10.1016/j.vaccine.2009.07.059⟩
Vaccine, Elsevier, 2009, 27 (42), pp.5772-80. ⟨10.1016/j.vaccine.2009.07.059⟩
Vaccine, 2009, 27 (42), pp.5772-80. ⟨10.1016/j.vaccine.2009.07.059⟩
International audience; We aimed at improving DNA vaccination efficiency for inducing neutralizing antibodies. We used plasmids encoding Gag of MLV and envelope proteins of VSV or WNV. Upon in vivo injection, they generate retrovirus-derived VLPs pse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91a6e8f8edb14ab2751d0ebc05ee7d98
https://hal.archives-ouvertes.fr/hal-00420201
https://hal.archives-ouvertes.fr/hal-00420201
Autor:
Stefan Kochanek, Bertrand Bellier, Delphine Desjardins, David Klatzmann, Charlotte Dalba, François-Loïc Cosset, Frédéric Tangy, Christophe Huret, Florian Kreppel
Publikováno v:
The Journal of Gene Medicine
The Journal of Gene Medicine, 2009, 11 (4), pp.313-25. ⟨10.1002/jgm.1307⟩
The Journal of Gene Medicine, Wiley, 2009, 11 (4), pp.313-25. ⟨10.1002/jgm.1307⟩
The Journal of Gene Medicine, 2009, 11 (4), pp.313-25. ⟨10.1002/jgm.1307⟩
The Journal of Gene Medicine, Wiley, 2009, 11 (4), pp.313-25. ⟨10.1002/jgm.1307⟩
International audience; BACKGROUND: The expression of Moloney murine leukemia virus (Mo-MLV) gag proteins is sufficient to generate retrovirus-like particles (retroVLPs) that can be used as antigen-display platforms by pseudotyping with heterologous
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::faeabc2fdf831441a3e3f97725b591e7
https://hal-pasteur.archives-ouvertes.fr/pasteur-00384279
https://hal-pasteur.archives-ouvertes.fr/pasteur-00384279
Autor:
Rosybel Drury, David Klatzmann, Charlotte Dalba, Mary Collins, Béatrice Clerc, Delphine Desjardins, Bertrand Bellier, François-Loïc Cosset
Publikováno v:
Vaccine. 24(14)
Virus-like particle (VLP)-based vaccines have provided highly encouraging results in clinical trials while, in contrast, DNA vaccines expressing non-particulate proteins have proven less successful. Seeking to combine the immunogenicity of VLPs and t