Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Charlotte D. Stratton"'
Autor:
Michael William Wilson, Milton L. Hoefle, D. R. Sliskovic, Roger S. Newton, Bruce D. Roth, Charlotte D. Stratton, Daniel F. Ortwine
Publikováno v:
Journal of Medicinal Chemistry. 33:21-31
A novel series of trans-6-(2-pyrrol-1-ylethyl)-4-hydroxypyran-2-ones and their dihydroxy acid derivatives were prepared and evaluated for their ability to inhibit the enzyme HMG-CoA reductase in vitro. A systematic study of substitution at the 2- and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1694558173f4f71e10bcba1d30878f3
https://doi.org/10.1021/jm00163a005
https://doi.org/10.1021/jm00163a005
Autor:
Bruce D. Roth, C. J. Blankley, Catherine Sekerke, E. Ferguson, A. W. Chucholowski, Milton L. Hoefle, Roger S. Newton, Charlotte D. Stratton, Daniel F. Ortwine, D. R. Sliskovic
Publikováno v:
Journal of medicinal chemistry. 34(1)
A series of trans-tetrahydro-4-hydroxy-6-[2-(2,3,4,5-substituted-1H-pyrrol-1-yl) ethyl]-2H-pyran-2-ones and their dihydroxy acids were prepared and tested for their ability to inhibit the enzyme HMG-CoA reductase in vitro. Inhibitory potency was foun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8cc1f80872bfb6e374a7d67e1aac12d
https://pubmed.ncbi.nlm.nih.gov/1992137
https://pubmed.ncbi.nlm.nih.gov/1992137
Autor:
Michael W. Wilson, Milton L. Hoefle, Roger S. Newton, Charlotte D. Stratton, Bruce D. Roth, D. R. Sliskovic, Daniel F. Ortwine
Publikováno v:
ChemInform. 21
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::45b5111decd8782d1f7cab27865353a4
https://doi.org/10.1002/chin.199022161
https://doi.org/10.1002/chin.199022161
Publikováno v:
Journal of the American Chemical Society. 77:4054-4058
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2dfc12c6d61c0a00e83e53246f6656eb
https://doi.org/10.1021/ja01620a027
https://doi.org/10.1021/ja01620a027
Publikováno v:
Journal of the American Chemical Society. 77:3082-3086
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::544ce4a44c121fa89af469ae04c31d25
https://doi.org/10.1021/ja01616a044
https://doi.org/10.1021/ja01616a044
Publikováno v:
Journal of the American Chemical Society. 77:24-26
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::53277731d4406323adc8438e1750d322
https://doi.org/10.1021/ja01606a006
https://doi.org/10.1021/ja01606a006
Autor:
Charlotte D. Stratton, Milton L. Hoefle, Ruth M. Corey, Robert F. Meyer, Stephen G. Hastings, Ann Holmes
Publikováno v:
Journal of medicinal chemistry. 18(2)
A series of 1-amino-3-aryloxy-2-propanols has been synthesized and examined for cardioselective beta-blockade. The introduction of the (3,4-dimethoxyphenethyl)amino group lead to the most cardioselective agents. Structure-activity relationships are d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8e2f75b8d75a6e54ca00d8d4a57fba0
https://pubmed.ncbi.nlm.nih.gov/235644
https://pubmed.ncbi.nlm.nih.gov/235644
Publikováno v:
Chemischer Informationsdienst. 5
Eine Reihe von Methylheterocyclen (I) wird in Form ihrer Lithiumderivate (II) mit den Aminoacetonitrilen (III) zu den Enaminen (IV) umgesetzt, die durch Hydrolyse, Reduktion mit Natriumborhydrid und hydrierende Debenzylierung in Propanolamine (VII) u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5195af896cf69343101b6ec6e4b234c8
https://doi.org/10.1002/chin.197404242
https://doi.org/10.1002/chin.197404242
Autor:
Charlotte D. Stratton, Milton L. Hoefle, Ruth M. Corey, Robert F. Meyer, Ann Holmes, Stephen G. Hastings
Publikováno v:
Chemischer Informationsdienst. 6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b55f04f2cefdef1a2767494238c7530e
https://doi.org/10.1002/chin.197524227
https://doi.org/10.1002/chin.197524227
Publikováno v:
Journal of medicinal chemistry. 16(10)
Eine Reihe von Methylheterocyclen (I) wird in Form ihrer Lithiumderivate (II) mit den Aminoacetonitrilen (III) zu den Enaminen (IV) umgesetzt, die durch Hydrolyse, Reduktion mit Natriumborhydrid und hydrierende Debenzylierung in Propanolamine (VII) u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2af3cf1ee29a3627eea00bef1774cb2c
https://pubmed.ncbi.nlm.nih.gov/4147942
https://pubmed.ncbi.nlm.nih.gov/4147942