Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Charlotte D, Koopman"'
Autor:
Catharina Hagerling, Mark Owyong, Vaishnavi Sitarama, Chih-Yang Wang, Charlene Lin, Renske J. E. van den Bijgaart, Charlotte D. Koopman, Audrey Brenot, Ankitha Nanjaraj, Fredrik Wärnberg, Karin Jirström, Ophir D. Klein, Zena Werb, Vicki Plaks
Publikováno v:
BMC Cancer, Vol 20, Iss 1, Pp 1-14 (2020)
Abstract Background Novel biomarkers are required to discern between breast tumors that should be targeted for treatment from those that would never become clinically apparent and/or life threatening for patients. Moreover, therapeutics that specific
Externí odkaz:
https://doaj.org/article/dfb15e4168e94a338324b032b6ed7f9b
Autor:
Christiaan C. Veerman, Isabella Mengarelli, Charlotte D. Koopman, Ronald Wilders, Shirley C. van Amersfoorth, Diane Bakker, Rianne Wolswinkel, Mariam Hababa, Teun P. de Boer, Kaomei Guan, James Milnes, Elisabeth M. Lodder, Jeroen Bakkers, Arie O. Verkerk, Connie R. Bezzina
Publikováno v:
Disease Models & Mechanisms, Vol 12, Iss 7 (2019)
Mutations in GNB5, encoding the G-protein β5 subunit (Gβ5), have recently been linked to a multisystem disorder that includes severe bradycardia. Here, we investigated the mechanism underlying bradycardia caused by the recessive p.S81L Gβ5 variant
Externí odkaz:
https://doaj.org/article/9a0498e951bf479a8ce5b96fc11940df
Autor:
Sarah M. Kamel, Charlotte D. Koopman, Fabian Kruse, Sven Willekers, Sonja Chocron, Jeroen Bakkers
Publikováno v:
Journal of Cardiovascular Development and Disease, Vol 8, Iss 4, p 46 (2021)
Cardiomyopathies are a group of heterogeneous diseases that affect the muscles of the heart, leading to early morbidity and mortality in young and adults. Genetic forms of cardiomyopathy are caused predominantly by mutations in structural components
Externí odkaz:
https://doaj.org/article/2fbde33ac8bb495fac405f101a7f4447
Autor:
Jeroen Bakkers, Teun P. de Boer, Mohankrishna Dalvoy Vasudevarao, Alberto Bertozzi, Medhanie A. Mulaw, Charlotte D. Koopman, Chi-Chung Wu, Phong D. Nguyen, Gilbert Weidinger
Publikováno v:
Developmental Biology. Academic Press
Adult zebrafish are frequently described to be able to "completely" regenerate the heart. Yet, the extent to which cardiomyocytes lost to injury are replaced is unknown, since existing evidence for cardiomyocyte proliferation is indirect or non-quant
Autor:
Mart M. Lamers, Anna Z. Mykytyn, Tim I. Breugem, Nathalie Groen, Kèvin Knoops, Debby Schipper, Romy van Acker, Petra B. van den Doel, Theo Bestebroer, Charlotte D. Koopman, Chantal Reusken, Mauro J. Muraro, Corine H. GeurtsvanKessel, Martin E. van Royen, Peter J. Peters, Jingshu Zhang, Bart L. Haagmans
In late 2021, the highly mutated SARS-CoV-2 Omicron variant emerged, raising concerns about its potential extensive immune evasion, increased transmissibility and pathogenicity. Here, we used organoids of the human airways and alveoli to investigate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b3de76be0e0d44da42189162b43c4f81
https://doi.org/10.1101/2022.01.19.476898
https://doi.org/10.1101/2022.01.19.476898
Autor:
Corine C GeurtsvanKessel, Jelte van der Vaart, Bart L. Haagmans, Nathalie Groen, Yiquan Wang, Mauro J. Muraro, Charlotte D. Koopman, Nicholas C. Wu, Tim I Breugem, Kèvin Knoops, Jingshu Zhang, Debby Schipper, Anna Z Mykytyn, Mart M. Lamers, Peter J. Peters, Hans Clevers, Theo M. Bestebroer, Petra B. van den Doel, Douglas C. Wu
A new phase of the COVID-19 pandemic has started as several SARS-CoV-2 variants are rapidly emerging globally, raising concerns for increased transmissibility. As animal models and traditional in vitro systems may fail to model key aspects of the SAR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b77308fc620868cb3445e22459e96d08
https://doi.org/10.1101/2021.05.03.441080
https://doi.org/10.1101/2021.05.03.441080
Autor:
Fabian Kruse, Sarah M. Kamel, Jeroen Bakkers, Sven Willekers, Sonja Chocron, Charlotte D. Koopman
Publikováno v:
Journal of Cardiovascular Development and Disease
Volume 8
Issue 4
Journal of Cardiovascular Development and Disease, Vol 8, Iss 46, p 46 (2021)
Journal of Cardiovascular Development and Disease, 8(4). Multidisciplinary Digital Publishing Institute (MDPI)
Volume 8
Issue 4
Journal of Cardiovascular Development and Disease, Vol 8, Iss 46, p 46 (2021)
Journal of Cardiovascular Development and Disease, 8(4). Multidisciplinary Digital Publishing Institute (MDPI)
Cardiomyopathies are a group of heterogeneous diseases that affect the muscles of the heart, leading to early morbidity and mortality in young and adults. Genetic forms of cardiomyopathy are caused predominantly by mutations in structural components
Autor:
Peter J. Peters, Bart L. Haagmans, Nathalie Groen, Jelte van der Vaart, Debby Schipper, Jeroen Demmers, Kèvin Knoops, Tim I Breugem, Hans Duimel, Hans Clevers, Marion Koopmans, Mauro J. Muraro, Samra Riesebosch, Joep Beumer, Karel Bezstarosti, Georges M. G. M. Verjans, Anna Z Mykytyn, Mart M. Lamers, Raimond B. G. Ravelli, Charlotte D. Koopman
Publikováno v:
EMBO Journal. Nature Publishing Group
The EMBO Journal
The Embo Journal, 40(5):105912. Wiley
EMBO Journal, 40(5):e105912. Wiley-Blackwell
The EMBO Journal
The Embo Journal, 40(5):105912. Wiley
EMBO Journal, 40(5):e105912. Wiley-Blackwell
Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) causes coronavirus disease 2019 (COVID‐19), which may result in acute respiratory distress syndrome (ARDS), multiorgan failure, and death. The alveolar epithelium is a major target of
Autor:
Charlotte D, Koopman, Jessica, De Angelis, Swati P, Iyer, Arie O, Verkerk, Jason, Da Silva, Geza, Berecki, Angela, Jeanes, Gregory J, Baillie, Scott, Paterson, Veronica, Uribe, Ophelia V, Ehrlich, Samuel D, Robinson, Laurence, Garric, Steven, Petrou, Cas, Simons, Irina, Vetter, Benjamin M, Hogan, Teun P, de Boer, Jeroen, Bakkers, Kelly A, Smith
Publikováno v:
Proc Natl Acad Sci U S A
The establishment of cardiac function in the developing embryo is essential to ensure blood flow and, therefore, growth and survival of the animal. The molecular mechanisms controlling normal cardiac rhythm remain to be fully elucidated. From a forwa
Autor:
Benjamin M. Hogan, Angela Jeanes, Steven Petrou, Geza Berecki, Laurence Garric, Ophelia V. Ehrlich, Irina Vetter, Cas Simons, Teun P. de Boer, Charlotte D. Koopman, Samuel D. Robinson, Swati Iyer, Veronica Uribe, Scott Paterson, Jason Da Silva, Arie O. Verkerk, Gregory J. Baillie, Jessica E. De Angelis, Jeroen Bakkers, Kelly A. Smith
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 118(9). National Academy of Sciences
Proceedings of the National Academy of Sciences of the United States of America, 118(9):e2018220118. National Academy of Sciences
Proceedings of the National Academy of Sciences of the United States of America, 118(9):e2018220118. National Academy of Sciences
The establishment of cardiac function in the developing embryo is essential to ensure blood flow and, therefore, growth and survival of the animal. The molecular mechanisms controlling normal cardiac rhythm remain to be fully elucidated. From a forwa