Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Charlotte C. Dodd"'
Autor:
Claire J. Sadler, B. Kevin Park, Stephen A. Ward, Sharon L. Smith, Charlotte C. Dodd, W. Graham McLean, Geoffrey Edwards
Publikováno v:
Biochemical Pharmacology. 61:409-416
The role of antioxidants in the neurotoxicity of the antimalarial endoperoxides artemether and dihydroartemisinin was studied in vitro by quantitative image analysis of neurite outgrowth in the neuroblastoma cell line NB2a. Intracellular glutathione
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::abf98f36c4e54d3ad8605d7dda909204
https://doi.org/10.1016/s0006-2952(00)00556-6
https://doi.org/10.1016/s0006-2952(00)00556-6
Autor:
Munir Pirmohamed, B. Kevin Park, Helen Powell, Dennis A. Smith, Y Clement, Charlotte C. Dodd, Lesley I. McLellan, Neil R. Kitteringham, Justice N. Tettey
Publikováno v:
Hepatology. 32:321-333
Exposure of cells to toxic chemical species can result in reduced glutathione (GSH) depletion, generation of free radicals, and/or binding to critical cell determinants. Chemical stress is usually followed by a concerted cellular response aimed at re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6544966fbd84e81a2005d238adf6fd1
https://doi.org/10.1053/jhep.2000.9602
https://doi.org/10.1053/jhep.2000.9602
Autor:
Kenneth F. Ilett, James L. Maggs, B. Kevin Park, Kevin T. Batty, Charlotte C. Dodd, Geoffrey Edwards, Paul M. O'Neill, Laurence P. D. Bishop
Publikováno v:
Chemico-biological interactions. 147(2)
Arteflene is a synthetic endoperoxide antimalarial. Its peroxide bridge undergoes iron(II)-mediated reduction in vitro which yields a carbon-centered cyclohexyl radical and a mixture of cis- and trans-alpha,beta-unsaturated ketones (enones). The enon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1232ae7512938ac852d51ca48be5debd
https://pubmed.ncbi.nlm.nih.gov/15013819
https://pubmed.ncbi.nlm.nih.gov/15013819
Autor:
Werner J. Pichler, Dean J. Naisbitt, John Farrell, Claire A. Gibney, Munir Pirmohamed, Gavin Wong, Charlotte C. Dodd, David Chadwick, Josephine E. Hopkins, B. Kevin Park, Jan P.H. Depta
Publikováno v:
The Journal of allergy and clinical immunology. 111(6)
Background: Lamotrigine is associated with hypersensitivity reactions, which are most commonly characterized by skin rash. An immune etiology has been postulated, though the nature of this is unclear. Objectives: The aim of this study was to characte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a20d8cf81a1107a3fb950f65d859096
https://pubmed.ncbi.nlm.nih.gov/12789244
https://pubmed.ncbi.nlm.nih.gov/12789244