Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Charlotte Bellamy"'
Autor:
Sangita Pal, Adam Boynton, Ryan Johnston, Naomi Currimjee, Kenin Qian, Mehdi Touat, Charlotte Bellamy, Patricia Ho, David Root, Nicole Persky, Amy Goodale, Jim Berstler, Lisa Miller, Alex Guletsky, Marta Cortes-Cros, Keith Ligon, Rameen Beroukhim, Pratiti Bandopadhayay
Publikováno v:
Neuro-Oncology. 24:vii231-vii232
Approximately 25% of recurrent gliomas exhibit hypermutation, which is most often acquired in chemotherapy sensitive gliomas post-treatment with standard of care alkylating agent temozolomide, Intriguingly, nearly all of these recurrent hypermutant t
Autor:
Florence Coulet, Jill S. Barnholtz-Sloan, Marc Sanson, Adam Boynton, Aniket Shetty, Yvonne Y. Li, Tracy T. Batchelor, Marine Giry, Garrett M. Frampton, Alexandre Carpentier, Peter J. Park, Franck Bielle, Eudocia Q. Lee, Khê Hoang-Xuan, Jean-Yves Delattre, Leon Taquet, Philippe Cornu, Erell Guillerm, Andrew D. Cherniack, Liam F. Spurr, Robert E. Jones, Mehdi Touat, Rameen Beroukhim, Patrick Y. Wen, J. Bryan Iorgulescu, David Meredith, Kristine Pelton, Caroline Dehais, Radwa Sharaf, Sandro Santagata, Alex Duval, Kenin Qian, Nadia Younan, Florence Laigle-Donadey, Patricia Ho, J Ricardo McFaline-Figueroa, Juliana Bonardi, Mary Jane Lim-Fat, David A. Reardon, Capucine Baldini, Naomi Currimjee, Shakti H. Ramkissoon, Caroline Houillier, Katie Pricola Fehnel, Seth Malinowski, Dimitri Psimaras, Cristina Birzu, Charlotte Bellamy, Isidro Cortes-Ciriano, Keith L. Ligon, Jack Geduldig, Karima Mokhtari, Maite Verreault, Lee A. Albacker, Pratiti Bandopadhayay, Bertrand Mathon, Susan N. Chi, E. Antonio Chiocca, Agusti Alentorn, Dean Pavlick, Frank Dubois, Sangita Pal, Samy Ammari, Brian M. Alexander, Arnab Chakravarti, Azra H. Ligon, Sanda Alexandrescu, Ahmed Idbaih, Frédéric Beuvon, Lakshmi Nayak, Laurent Capelle, Aurélien Marabelle, Daphne A. Haas-Kogan, Raymond Y. Huang, Craig L. Bohrson, Wenya Linda Bi, Ruben Ferrer-Luna, Kin-Hoe Chow
Publikováno v:
Nature
A high tumour mutational burden (hypermutation) is observed in some gliomas1–5; however, the mechanisms by which hypermutation develops and whether it predicts the response to immunotherapy are poorly understood. Here we comprehensively analyse the
Autor:
Bryan Iorgulescu, Mehdi Touat, Andrew D. Cherniack, Agusti Alentorn, David A. Reardon, Caroline Dehais, Rameen Beroukhim, Capucine Baldini, Khê Hoang-Xuan, Karima Mokhtari, Aurélien Marabelle, Alexandre Carpentier, Raymond Y. Huang, Alex Duval, Marc Sanson, Sangita Pal, Adam Boynton, Maite Verreault, Franck Bielle, Azra H. Ligon, Brian M. Alexander, Pratiti Bandopadhayay, Ennio Antonio Chiocca, David Meredith, Frédéric Beuvon, Erell Guillerm, Patrick Y. Wen, Lakshmi Nayak, Nadia Younan, Sandro Santagata, Florence Laigle-Donadey, Daphne A. Haas-Kogan, Ruben Ferrer-Luna, Florence Coulet, Jack Geduldig, Eudocia Q. Lee, Susan N. Chi, Sanda Alexandrescu, Jean-Yves Delattre, Wenya Bi, Christina Birzu, Samy Ammari, Ahmed Idbaih, Keith L. Ligon, Bertrand Mathon, Philippe Cornu, Liam F. Spurr, Yvonne Y. Li, Caroline Houiller, Charlotte Bellamy
Publikováno v:
Neuro Oncol
BACKGROUND Hypermutation is an emerging biomarker for predicting response to immunotherapy in cancer patients, however its clinical value in gliomas is not established. We sought to assess the determinants of hypermutation in gliomas, and its value f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82fc8a1adb5f5a8cd313903782f2363a
https://europepmc.org/articles/PMC6847135/
https://europepmc.org/articles/PMC6847135/
Autor:
Charlotte Bellamy
Publikováno v:
Food and History. 15:205-228
French cuisine is often thought of as an important illustration of a general European attraction to all things French in the eighteenth century. French cooks seem to have been in many, if not most,...
Autor:
Mehdi Touat, Kenin Qian, Patricia Ho, Sangita Pal, Jim Berstler, Pratiti Bandopadhayay, Adam Boynton, Charlotte Bellamy, Naomi Currimjee, Keith L. Ligon, Rameen Beroukhim
Publikováno v:
Neuro-Oncology
INTRODUCTION We have observed that approximately 26% of recurrent gliomas acquire hypermutation following treatment with temozolomide (TMZ). Intriguingly, 91% of these tumors harbor mutations in mismatch repair (MMR) genes. Strategies to target MMR-d
Autor:
Brian M. Alexander, Shakti H. Ramkissoon, Mehdi Touat, Seth Malinowski, Arnab Chakravarti, Philippe Cornu, Andrew D. Cherniack, Agusti Alentorn, Karima Mokhtari, Caroline Dehais, Jack Geduldig, Kenin Qian, Florence Laigle-Donadey, Maite Verreault, Kin-Hoe Chow, Jill S. Barnholtz-Sloan, Marc Sanson, Adam Boynton, Ahmed Idbaih, Dimitri Psimaras, Bertrand Mathon, Aniket Shetty, Sangita Pal, Yvonne Y. Li, Franck Bielle, Caroline Houillier, Laurent Capelle, Garrett M. Frampton, Craig L. Bohrson, Samy Ammari, Frank Dubois, David A. Reardon, Aurélien Marabelle, Liam F. Spurr, Mary J. Lim-Fat, Isidro Cortes-Ciriano, Erell Guillerm, Alexandre Carpentier, Pratiti Bandopadhayay, Frédéric Beuvon, Charlotte Bellamy, Kristine Pelton, Bryan Iorgulescu, Wenya Linda Bi, Peter J. Park, Patrick Y. Wen, Rameen Beroukhim, Naomi Currimjee, Keith L. Ligon
Publikováno v:
Cancer Research. 80:5705-5705
High tumor mutational burden (hypermutation) is observed in some gliomas; however, its mechanisms of development and whether it predicts immunotherapy response are poorly understood. Here, we comprehensively analyze the molecular determinants of muta
Autor:
Alastair Droop, David R. Westhead, Thomas J. R. Hughes, Josie Hayes, Susan C Short, Sean E. Lawler, Marjorie Boissinot, Helene Thygesen, Heiko Wurdak, Charlotte Bellamy, Lisa Shaw
Publikováno v:
Neuro-Oncology. 16:v25-v25
MicroRNAs are short non-coding RNAs that act as micro-managers of cellular function. Their dysregulation is well documented in many cancers. TCGA microRNA expression data is available to identify the prognostic potential of microRNAs in malignant gli