Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Charlotte Barbieux"'
Autor:
Tamara Casteels, Yufeng Zhang, Thomas Frogne, Caterina Sturtzel, Charles-Hugues Lardeau, Ilke Sen, Xiaocheng Liu, Shangyu Hong, Florian M. Pauler, Thomas Penz, Marlene Brandstetter, Charlotte Barbieux, Ekaterine Berishvili, Thomas Heuser, Christoph Bock, Christian G. Riedel, Dirk Meyer, Martin Distel, Jacob Hecksher-Sørensen, Jin Li, Stefan Kubicek
Publikováno v:
Molecular Metabolism, Vol 54, Iss , Pp 101329- (2021)
Objective: The loss of forkhead box protein O1 (FoxO1) signaling in response to metabolic stress contributes to the etiology of type II diabetes, causing the dedifferentiation of pancreatic beta cells to a cell type reminiscent of endocrine progenito
Externí odkaz:
https://doaj.org/article/a0e438a3cef045b6a78157d78619e54d
Autor:
Thierry M. Nordmann, Erez Dror, Friederike Schulze, Shuyang Traub, Ekaterine Berishvili, Charlotte Barbieux, Marianne Böni-Schnetzler, Marc Y. Donath
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
Abstract Chronic inflammation impairs insulin secretion and sensitivity. β-cell dedifferentiation has recently been proposed as a mechanism underlying β-cell failure in T2D. Yet the effect of inflammation on β-cell identity in T2D has not been stu
Externí odkaz:
https://doaj.org/article/6f906ade44424de0a8b12cce0ea33f04
Autor:
David Jackson-Perry, Lucie Vittoz, Ingrid Gilles, Alexandra Calmy, Isabelle Peytremann-Bridevaux, Charlotte Barbieux, Marco Alessandrini, Saphir Lesage
Publikováno v:
Journal of acquired immune deficiency syndromes, vol. 87, no. 5, pp. 1154-1160
BACKGROUND Recent advances made in cell and gene therapies for cancer suggest that they represent plausible strategies to cure HIV. However, the health risks and constraints associated with these therapies require a deeper understanding of the expect
Autor:
Nelly Courvoisier, Chiara Storari, Saphir Lesage, Lucie Vittoz, Charlotte Barbieux, Isabelle Peytremann‐Bridevaux, Ingrid Gilles, Alexandra Calmy
Publikováno v:
HIV medicine, vol. 23, no. 4, pp. 441-447
Women are underrepresented in most HIV clinical trials in Western countries, but their participation remains crucial as the lack of information on sex- and gender-specific effects may hinder the safety and efficacy of antiretroviral treatments. The a
Autor:
Enos Bernasconi, Charlotte Barbieux, Matthias Cavassini, Pietro Vernazza, Dominique L Braun, Delphine Sculier, Alexandra Calmy, Patrick Schmid, Laurent A. Decosterd, Monia Guidi, Perrine Courlet, Marcel Stoeckle, Gilles Wandeler, Huldrych F. Günthard, Mikaela Smit, Andreas Limacher, Susana Alves Saldanha, Annalisa Marinosci
Publikováno v:
British journal of clinical pharmacologyREFERENCES. 87(11)
This study aims to evaluate the association between dolutegravir (DTG) pharmacokinetic parameters and weight changes in treatment-experienced people with HIV (PWHIV) from the Simpl'HIV study newly switched to a dual DTG-based regimen. We used multiva
Autor:
Caterina Sturtzel, Florian M. Pauler, Jin Li, Thomas Penz, Jacob Hecksher-Sørensen, Thomas Frogne, Ekaterine Berishvili, Yufeng Zhang, Christian G. Riedel, Martin Distel, Shangyu Hong, Christoph Bock, Dirk Meyer, Ilke Sen, Thomas Heuser, Xiaocheng Liu, Stefan Kubicek, Marlene Brandstetter, Charlotte Barbieux, Tamara Casteels, Charles-Hugues Lardeau
Publikováno v:
Molecular metabolism, Vol. 54 (2021) P. 101329
Molecular Metabolism
Molecular Metabolism, Vol 54, Iss, Pp 101329-(2021)
Molecular Metabolism
Molecular Metabolism, Vol 54, Iss, Pp 101329-(2021)
Objective The loss of forkhead box protein O1 (FoxO1) signaling in response to metabolic stress contributes to the etiology of type II diabetes, causing the dedifferentiation of pancreatic beta cells to a cell type reminiscent of endocrine progenitor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6979005f2039a97781a78d413edaa0e0
https://archive-ouverte.unige.ch/unige:155411
https://archive-ouverte.unige.ch/unige:155411
Autor:
Jordi Altirriba, Sarah Mouche, Charlotte Barbieux, Ildiko Szanto, Christelle Veyrat-Durebex, Chris R. J. Kennedy, Domenico Bosco, Gerhard Christofori, Chet E. Holterman, Jenny E. Gunton, Thierry Berney, Alexis Forterre, Michel Pinget, Karim Bouzakri, William Bietiger, Mohamed Alibashe, Benjamin B. Tournier, Caroline Arous
Publikováno v:
Antioxidants and Redox Signaling
Antioxidants and Redox Signaling, Mary Ann Liebert, 2020, 32 (9), pp.618-635. ⟨10.1089/ars.2018.7579⟩
Antioxidants and Redox Signaling, Mary Ann Liebert, 2020, 32 (9), pp.618-635. ⟨10.1089/ars.2018.7579⟩
Aims: Nicotinamide adenine dinucleotide phosphate oxidases (NOX-es) produce reactive oxygen species and modulate β-cell insulin secretion. Islets of type 2 diabetic subjects present elevated expres...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7dfd6911e073298d180d271322f3a5c8
https://hal.archives-ouvertes.fr/hal-03336125
https://hal.archives-ouvertes.fr/hal-03336125
Autor:
Andreas Spittler, Stefan Kubicek, Ekaterine Berishvili, Christoph Bock, Charlotte Barbieux, Jin Li, Johanna Klughammer, Thomas Penz, Matthias Farlik
Publikováno v:
EMBO Reports
EMBO Reports, Vol. 17, No 2 (2016) pp. 178-187
Europe PubMed Central
EMBO Reports, Vol. 17, No 2 (2016) pp. 178-187
Europe PubMed Central
Pancreatic islets of Langerhans contain several specialized endocrine cell types, which are commonly identified by the expression of single marker genes. However, the established marker genes cannot capture the complete spectrum of cellular heterogen
Autor:
Raphael P. H. Meier, Mathieu Pierre Jean Armanet, Charlotte Barbieux, Domenico Bosco, Thierry Berney, Vanessa Lavallard, Géraldine Parnaud, Jeremy Meyer, Elisa Montanari, Philippe Morel
Publikováno v:
FASEB Journal, Vol. 30, No 2 (2016) pp. 748-60
FASEB journal : official publication of the Federation of American Societies for Experimental Biolog
FASEB journal : official publication of the Federation of American Societies for Experimental Biolog
The major feature of the human pancreatic islet architecture is the organization of endocrine cells into clusters comprising central β cells and peripheral α cells surrounded by vasculature. To have an insight into the mechanisms that govern this u
Autor:
Marc Y. Donath, Shuyang Traub, Marianne Böni-Schnetzler, Erez Dror, Friederike Schulze, Charlotte Barbieux, Ekaterine Berishvili, Thierry M. Nordmann
Publikováno v:
Scientific Reports
Scientific Reports, Vol. 7, No 1 (2017) P. 6285
Scientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
Scientific Reports, Vol. 7, No 1 (2017) P. 6285
Scientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
Chronic inflammation impairs insulin secretion and sensitivity. β-cell dedifferentiation has recently been proposed as a mechanism underlying β-cell failure in T2D. Yet the effect of inflammation on β-cell identity in T2D has not been studied. The