Výsledky vyhledávání - "Charlotte B, Smith"

Structural basis of paralog-specific KDM2A/B nucleosome recognition

Autor: Cathy J. Spangler, Aleksandra Skrajna, Caroline A. Foley, Anh Nguyen, Gabrielle R. Budziszewski, Dalal N. Azzam, Eyla C. Arteaga, Holly C. Simmons, Charlotte B. Smith, Nathaniel A. Wesley, Emily M. Wilkerson, Jeanne-Marie E. McPherson, Dmitri Kireev, Lindsey I. James, Stephen V. Frye, Dennis Goldfarb, Robert K. McGinty

Publikováno v: Nature Chemical Biology. 19:624-632

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e92720ce51947090d9ebe2b31e532414
https://doi.org/10.1038/s41589-023-01256-y

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The Effect of Angioembolization Versus Open Exploration for Moderate to Severe Blunt Liver Injuries on Mortality

Autor: Jared Gallaher, Victoria Burton, Andrew B. Schneider, Trista Reid, Lauren Raff, Charlotte B. Smith, Anthony Charles

Publikováno v: World Journal of Surgery. 47:1271-1281

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::532d1b14fbdc22881c80b32bb97ea89e
https://doi.org/10.1007/s00268-023-06926-5

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The Effects of Histone H2B Ubiquitylations on the Nucleosome Structure and Internucleosomal Interactions

Autor: Bhaswati Sengupta, Mai Huynh, Charlotte B. Smith, Robert K. McGinty, Wladyslaw Krajewski, Tae-Hee Lee

Publikováno v: Biochemistry. 61:2198-2205

Eukaryotic gene compaction takes place at multiple levels to package DNA to chromatin and chromosomes. Two of the most fundamental levels of DNA packaging are at the nucleosome and dinucleosome stacks. The nucleosome is the basic gene-packing unit an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b70a296202d994620e16a95de865ac58
https://doi.org/10.1021/acs.biochem.2c00422

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Comparison of Male and Female Surgeons’ Experiences With Gender Across 5 Qualitative/Quantitative Domains

Autor: Cheryl K, Zogg, Lyndsay A, Kandi, Hannah S, Thomas, Mary A, Siki, Ashley Y, Choi, Camila R, Guetter, Charlotte B, Smith, Erica, Maduakolam, Shreya, Kondle, Sharon L, Stein, Elizabeth A, Shaughnessy, Nita, Ahuja

Publikováno v: JAMA Surgery. 158:e226431

ImportanceA growing body of literature has been developed with the goal of attempting to understand the experiences of female surgeons. While it has helped to address inequities and promote important programmatic improvements, work remains to be done

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc7c9bbfe722942becf526b6417d3ddc
https://doi.org/10.1001/jamasurg.2022.6431

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Perceptions of differences in graduated autonomy between male and female surgical residents

Autor: April E. Mendoza, Charlotte B Smith, Noelle Saillant

Publikováno v: Surgery. 170(4)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d88106316d8a294726aa6458965deb9
https://pubmed.ncbi.nlm.nih.gov/33775394

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DOT1L activity in leukemia cells requires interaction with ubiquitylated H2B that promotes productive nucleosome binding

Autor: Cathy J. Spangler, Satya P. Yadav, Dongxu Li, Carinne N. Geil, Charlotte B. Smith, Gang Greg Wang, Tae-Hee Lee, Robert K. McGinty

Publikováno v: Cell Reports. 38:110369

DOT1L methylates histone H3 lysine 79 during transcriptional elongation and is stimulated by ubiquitylation of histone H2B lysine 120 (H2BK120ub) in a classical trans-histone crosstalk pathway. Aberrant genomic localization of DOT1L is implicated in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c45039034e72b189a3d4606d573a0dab
https://doi.org/10.1016/j.celrep.2022.110369

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Abstract 2082: Deciphering the nucleosome acidic patch binding at amino acid resolution

Autor: Charlotte B Smith, Robert K. McGinty, Holly Simmons, Jeanne-Marie E. Mcpherson, Aleksandra Skrajna, Dennis Goldfarb

Publikováno v: Cancer Research. 81:2082-2082

In all eukaryotic cells, nucleosomes provide basic organization of genomic DNA and serve as signaling hubs for gene expression, DNA replication and DNA damage repair. These genome-templated processes are tuned by chromatin enzymes that introduce chem

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4429f5fa6a46677e37668c9a70c3d1d5
https://doi.org/10.1158/1538-7445.am2021-2082

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Hypoglycemia Unawareness Is Associated With Reduced Adherence to Therapeutic Decisions in Patients With Type 1 Diabetes

Autor: Stephanie A. Amiel, Pratik Choudhary, A Pernet, Charlotte B. Smith, David Hopkins

Publikováno v: Diabetes Care

OBJECTIVE Hypoglycemia unawareness increases severe hypoglycemia risk. Hypoglycemia avoidance restores awareness, but it is difficult to sustain. We compared adherence to treatment changes by awareness status. RESEARCH DESIGN AND METHODS Case notes o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b91bb3a4a5f66f2f76f0250e2f2481a5
https://doi.org/10.2337/dc08-2259

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Hypoglycemia Unawareness Is Associated With Reduced Adherence to Therapeutic Decisions in Patients With Type 1 Diabetes: Evidence from a Clinical Audit

Autor: Charlotte B. Smith, David Hopkins, Pratik Choudhary, A Pernet, Stephanie A. Amiel

Publikováno v: Diabetes Care. 33:e16-e16

We thank Graveling and Frier (1) for their comments, which underline the clinical difficulties in managing patients with impaired awareness of hypoglycemia (IAH). An audit of a U.K.-based structured education program for patients with type 1 diabetes

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::195ce3471f8e88a102814f0b65aeb289
https://doi.org/10.2337/dc09-1847

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