The N-terminal domain of MX1 proteins is essential for their antiviral activity against different families of RNA viruses

Autor: Joe McKellar, Mary Arnaud-Arnould, Laurent Chaloin, Marine Tauziet, Charlotte Arpin-André, Oriane Pourcelot, Mickael Blaise, Olivier Moncorgé, Caroline Goujon

Myxovirus resistance protein 1 (MX1) and MX2, are homologous, dynamin-like large GTPases, induced upon interferon (IFN) exposure. Human MX1 (HsMX1) is known to inhibit many viruses, including influenza A virus (IAV), by likely acting at various steps

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e8795fefca906fef94c6a373093e6770
https://doi.org/10.1101/2022.05.10.491305

The PDZ Domain-binding Motif of the Human T Cell Leukemia Virus Type 1 Tax Protein Induces Mislocalization of the Tumor Suppressor hScrib in T cells

Autor: Jean-Michel Mesnard, Charlotte Arpin-André

Publikováno v: Journal of Biological Chemistry
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2007, 282 (45), pp.33132-41. ⟨10.1074/jbc.M702279200⟩

International audience; Interactions with cellular PDZ domain-containing proteins obviously contribute to the tumorigenic potential of several viral oncoproteins. In this regard, the oncogenic potential of the human T cell leukemia virus type 1 Tax p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::174f1ef4a5f5c95fcc7f071e35845a77
https://doi.org/10.1074/jbc.m702279200

Polarized expression of the membrane ASP protein derived from HIV-1 antisense transcription in T cells

Autor: Sylvain Laverdure, Benoit Barbeau, Antoine Gross, Laurence Briant, Cynthia Torresilla, Sophie Borel, Sébastien Landry, Charlotte Arpin-André, Isabelle Clerc, Amandine Vargas, Jean-Michel Mesnard

Publikováno v: Retrovirology
Retrovirology, BioMed Central, 2011, 8 (1), pp.74. ⟨10.1186/1742-4690-8-74⟩
Retrovirology, Vol 8, Iss 1, p 74 (2011)

Background Retroviral gene expression generally depends on a full-length transcript that initiates in the 5' LTR, which is either left unspliced or alternatively spliced. We and others have demonstrated the existence of antisense transcription initia

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cebf8b2ab0be75461c24b1c8bb6fab6c
https://hal.archives-ouvertes.fr/hal-02146256

HTLV-I antisense transcripts initiating in the 3'LTR are alternatively spliced and polyadenylated

Autor: Brigitte Audet, Marie-Hélène Cavanagh, Marie-Ève Paré, Susan J. Marriott, Eric Wattel, Patrick Hivin, Jean-Michel Mesnard, Julien Thête, Sébastien Landry, Charlotte Arpin-André, Benoit Barbeau

Publikováno v: Retrovirology
Retrovirology, BioMed Central, 2006, 3, pp.15. ⟨10.1186/1742-4690-3-15⟩
Retrovirology, Vol 3, Iss 1, p 15 (2006)
Retrovirology, 2006, 3, pp.15. ⟨10.1186/1742-4690-3-15⟩

Background Antisense transcription in retroviruses has been suggested for both HIV-1 and HTLV-I, although the existence and coding potential of these transcripts remain controversial. Thorough characterization is required to demonstrate the existence

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90b39e9855ad1797a750cc61ef515d4c
https://hal.archives-ouvertes.fr/hal-00188413/file/2006transcrit.pdf

Nuclear localization of HTLV-I bZIP factor (HBZ) is mediated by three distinct motifs

Autor: Patrick Hivin, Mélissa Frédéric, Charlotte Arpin-André, Jihane Basbous, Bernard Gay, Sabine Thébault, Jean-Michel Mesnard

Publikováno v: Journal of Cell Science, 118, Pt 7, pp. 1355-62
Journal of Cell Science, 118, 1355-62
Journal of Cell Science
Journal of Cell Science, 2005, 118 (Pt 7), pp.1355-62. ⟨10.1242/jcs.01727⟩
Journal of Cell Science, Company of Biologists, 2005, 118 (Pt 7), pp.1355-62. ⟨10.1242/jcs.01727⟩

Contains fulltext : 48999thebault.pdf (Publisher’s version ) (Open Access) The genome of the human T-cell leukemia virus type I (HTLV-I) codes for a basic leucine zipper protein, HBZ, capable of repressing JUN activity and viral transcription. Tran

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f45dc4214f9454431af028181f9d17ac
https://pubmed.ncbi.nlm.nih.gov/15755797