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pro vyhledávání: '"Charlotte A. René"'
Autor:
Charlotte A. René, Robin J. Parks
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 32, Iss 2, Pp 101259- (2024)
Extracellular vesicles (EVs) have the innate ability to carry proteins, lipids, and nucleic acids between cells, and thus these vesicles have gained much attention as potential therapeutic delivery vehicles. Many strategies have been explored to enha
Externí odkaz:
https://doaj.org/article/8ec31dbd06434b5cb03a299bdbb36d5a
Autor:
Charlotte A. René, Robin J. Parks
Publikováno v:
Pharmaceutics, Vol 15, Iss 6, p 1764 (2023)
Spinal muscular atrophy (SMA) is a devastating neuromuscular disorder caused by mutations in the survival of motor neuron 1 (SMN1) gene, which leads to a reduced level in the SMN protein within cells. Patients with SMA suffer from a loss of alpha mot
Externí odkaz:
https://doaj.org/article/b8ce72cff56f406696813e1c141d2ace
Autor:
Charlotte A. René, Robin J. Parks
Publikováno v:
Pharmaceutics, Vol 13, Iss 4, p 492 (2021)
The central nervous system (CNS) is surrounded by the blood–brain barrier (BBB), a semipermeable border of endothelial cells that prevents pathogens, solutes and most molecules from non-selectively crossing into the CNS. Thus, the BBB acts to prote
Externí odkaz:
https://doaj.org/article/de49e44a07364831b0e7c0f155856667
Autor:
Robin J. Parks, Charlotte A. René
Publikováno v:
Pharmaceutics
Pharmaceutics, Vol 13, Iss 492, p 492 (2021)
Pharmaceutics, Vol 13, Iss 492, p 492 (2021)
The central nervous system (CNS) is surrounded by the blood–brain barrier (BBB), a semipermeable border of endothelial cells that prevents pathogens, solutes and most molecules from non-selectively crossing into the CNS. Thus, the BBB acts to prote