Zobrazeno 1 - 10
of 81
pro vyhledávání: '"Charlotte A. Nelson"'
Autor:
Karthik Soman, Charlotte A. Nelson, Gabriel Cerono, Samuel M. Goldman, Sergio E. Baranzini, Ethan G. Brown
Publikováno v:
Frontiers in Medicine, Vol 10 (2023)
IntroductionEarly diagnosis of Parkinson’s disease (PD) is important to identify treatments to slow neurodegeneration. People who develop PD often have symptoms before the disease manifests and may be coded as diagnoses in the electronic health rec
Externí odkaz:
https://doaj.org/article/814bed3af30e4b41b23cf6ab26fbd7ec
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
The Scalable Precision Medicine Oriented Knowledge Engine (SPOKE) is a heterogeneous knowledge network that integrates information from 29 public databases. Here, Nelson et al. extend SPOKE to embed clinical data from electronic health records to cre
Externí odkaz:
https://doaj.org/article/ec5f2e03ddca4481a742ae0cece62da4
Autor:
Charlotte A. Nelson, Ana Uriarte Acuna, Amber M. Paul, Ryan T. Scott, Atul J. Butte, Egle Cekanaviciute, Sergio E. Baranzini, Sylvain V. Costes
Publikováno v:
Life, Vol 11, Iss 1, p 42 (2021)
There has long been an interest in understanding how the hazards from spaceflight may trigger or exacerbate human diseases. With the goal of advancing our knowledge on physiological changes during space travel, NASA GeneLab provides an open-source re
Externí odkaz:
https://doaj.org/article/de327389693b4a0681912ce532aa710d
Autor:
David Mavor, Kyle A. Barlow, Daniel Asarnow, Yuliya Birman, Derek Britain, Weilin Chen, Evan M. Green, Lillian R. Kenner, Bruk Mensa, Leanna S. Morinishi, Charlotte A. Nelson, Erin M. Poss, Pooja Suresh, Ruilin Tian, Taylor Arhar, Beatrice E. Ary, David P. Bauer, Ian D. Bergman, Rachel M. Brunetti, Cynthia M. Chio, Shizhong A. Dai, Miles S. Dickinson, Susanna K. Elledge, Cole V. M. Helsell, Nathan L. Hendel, Emily Kang, Nadja Kern, Matvei S. Khoroshkin, Lisa L. Kirkemo, Greyson R. Lewis, Kevin Lou, Wesley M. Marin, Alison M. Maxwell, Peter F. McTigue, Douglas Myers-Turnbull, Tamas L. Nagy, Andrew M. Natale, Keely Oltion, Sergei Pourmal, Gabriel K. Reder, Nicholas J. Rettko, Peter J. Rohweder, Daniel M. C Schwarz, Sophia K. Tan, Paul V. Thomas, Ryan W. Tibble, Jason P. Town, Mary K. Tsai, Fatima S. Ugur, Douglas R. Wassarman, Alexander M. Wolff, Taia S. Wu, Derek Bogdanoff, Jennifer Li, Kurt S. Thorn, Shane O'Conchúir, Danielle L. Swaney, Eric D. Chow, Hiten D. Madhani, Sy Redding, Daniel N. Bolon, Tanja Kortemme, Joseph L. DeRisi, Martin Kampmann, James S. Fraser
Publikováno v:
Biology Open, Vol 7, Iss 7 (2018)
Although the primary protein sequence of ubiquitin (Ub) is extremely stable over evolutionary time, it is highly tolerant to mutation during selection experiments performed in the laboratory. We have proposed that this discrepancy results from the di
Externí odkaz:
https://doaj.org/article/120375a9425d4b15800ba82e59af4543
Autor:
Siân de Bell, Julius Cesar Alejandre, Claudia Menzel, Rita Sousa-Silva, Tanja M. Straka, Susanne Berzborn, Max Bürck-Gemassmer, Martin Dallimer, Chris Dayson, Jessica C. Fisher, Annette Haywood, Alina Herrmann, Gisela Immich, Christian S. Keßler, Kristin Köhler, Mary Lynch, Viola Marx, Andreas Michalsen, Pierpaolo Mudu, Hendrik Napierala, Maximilian Nawrath, Sharon Pfleger, Claudia Quitmann, Jonathan P. Reeves, Kevin Rozario, Wolfgang Straff, Katie Walter, Charlotte Wendelboe-Nelson, Melissa R. Marselle, Rachel Rui Ying Oh, Aletta Bonn
Publikováno v:
Environment International, Vol 190, Iss , Pp 108801- (2024)
Background: Evidence on the health benefits of spending time in nature has highlighted the importance of provision of blue and green spaces where people live. The potential for health benefits offered by nature exposure, however, extends beyond healt
Externí odkaz:
https://doaj.org/article/fd7f12358a1645329eacb6b1f8c6cfa5
Autor:
Kate Lamont, Hugo C. van Woerden, Emma King, Charlotte Wendelboe-Nelson, Roger W. Humphry, Cameron Stark, Chris Williams, Margaret Maxwell
Publikováno v:
Discover Mental Health, Vol 4, Iss 1, Pp 1-11 (2024)
Abstract Background The farming community have high rates of poor mental health, and are relatively ‘hard to reach’ with mental health services. The aim of this study was therefore to undertake a feasibility RCT, based on two mental health interv
Externí odkaz:
https://doaj.org/article/bbd432fa06174addbc5809eadc4f87b3
Autor:
Charlotte Wendelboe-Nelson, Yiyun Wang, Simon Bell, Craig W. McDougall, Catharine Ward Thompson
Publikováno v:
Land, Vol 13, Iss 3, p 395 (2024)
Access to urban green and blue spaces (UGBSs) has been associated with positive effects on health and wellbeing; however, the past decades have seen a decline in quality and user satisfaction with UGBSs. This reflects the mounting challenges that man
Externí odkaz:
https://doaj.org/article/751dc5656bd8461f8d40e4ded340b5d1
Autor:
Edward Cunningham-Oakes, Yan Li, Blanca Perez-Sepulveda, Jay C. D. Hinton, Charlotte A. Nelson, K. Marie McIntyre, Maya Wardeh, Miren Iturriza-Gómara, Christiane Hertz-Fowler, Sarah J. O’Brien, Nigel A. Cunliffe, Alistair C. Darby
BackgroundTraditional laboratory-based surveillance of gastrointestinal pathogens is time-consuming, which can impact successful outbreak detection. The INTEGRATE study investigated the utility of metagenomic and metatranscriptomic sequencing for the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fdd066916fcd3b3176a5537f8d3be703
https://doi.org/10.1101/2023.04.03.23288067
https://doi.org/10.1101/2023.04.03.23288067
Autor:
John H Morris, Karthik Soman, Rabia E Akbas, Xiaoyuan Zhou, Brett Smith, Elaine C Meng, Conrad C Huang, Gabriel Cerono, Gundolf Schenk, Angela Rizk-Jackson, Adil Harroud, Lauren Sanders, Sylvain V Costes, Krish Bharat, Arjun Chakraborty, Alexander R Pico, Taline Mardirossian, Michael Keiser, Alice Tang, Josef Hardi, Yongmei Shi, Mark Musen, Sharat Israni, Sui Huang, Peter W Rose, Charlotte A Nelson, Sergio E Baranzini
Publikováno v:
Bioinformatics (Oxford, England), vol 39, iss 2
MotivationKnowledge graphs (KGs) are being adopted in industry, commerce and academia. Biomedical KG presents a challenge due to the complexity, size and heterogeneity of the underlying information.ResultsIn this work, we present the Scalable Precisi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08999d208d9350af4cd8a25a2c9dd7a4
https://escholarship.org/uc/item/12z7n7k5
https://escholarship.org/uc/item/12z7n7k5
Publikováno v:
Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing. 28
Meaningful representations of clinical data using embedding vectors is a pivotal step to invoke any machine learning (ML) algorithm for data inference. In this article, we propose a time-aware embedding approach of electronic health records onto a bi