Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Charlotte A. Green"'
Autor:
Charlotte A. Green, Nitin S. Kamble, Elizabeth K. Court, Owain J. Bryant, Matthew G. Hicks, Christopher Lennon, Gillian M. Fraser, Phillip C. Wright, Graham P. Stafford
Publikováno v:
Microbial Cell Factories, Vol 18, Iss 1, Pp 1-17 (2019)
Abstract Background Many valuable biopharmaceutical and biotechnological proteins have been produced in Escherichia coli, however these proteins are almost exclusively localised in the cytoplasm or periplasm. This presents challenges for purification
Externí odkaz:
https://doaj.org/article/e452668ad75543f096a42f8f752f7056
Autor:
Clare E. West, Mohd Karim, Maria J. Falaguera, Leo Speidel, Charlotte J. Green, Lisa Logie, Jeremy Schwartzentruber, David Ochoa, Janet M. Lord, Michael A. J. Ferguson, Chas Bountra, Graeme F. Wilkinson, Beverley Vaughan, Andrew R. Leach, Ian Dunham, Brian D. Marsden
Publikováno v:
Scientific Data, Vol 10, Iss 1, Pp 1-13 (2023)
Abstract Advancing age is the greatest risk factor for developing multiple age-related diseases. Therapeutic approaches targeting the underlying pathways of ageing, rather than individual diseases, may be an effective way to treat and prevent age-rel
Externí odkaz:
https://doaj.org/article/bd0a4e946edc4e929857d3968138af9c
Autor:
Leanne Hodson, Sion A. Parry, Thomas Cornfield, Catriona Charlton, Wee Suan Low, Charlotte J. Green, Fredrik Rosqvist
Publikováno v:
Upsala Journal of Medical Sciences, Vol 125, Iss 3, Pp 211-216 (2020)
Background: Hepatic de novo lipogenesis (DNL) is ideally measured in very low-density lipoprotein (VLDL)-triacylglycerol (TAG). In the fasting state, the majority of plasma TAG typically represents VLDL-TAG; however, the merits of measuring DNL in to
Externí odkaz:
https://doaj.org/article/1d2f612ccf0746d68d320dee8ba74e3a
Autor:
Thomas Marjot, Charlotte J Green, Catriona A Charlton, Thomas Cornfield, Jonathan Hazlehurst, Ahmad Moolla, Sarah White, Jane Francis, Stefan Neubauer, Jeremy FL Cobbold, Leanne Hodson, Jeremy W Tomlinson
Publikováno v:
JGH Open, Vol 4, Iss 3, Pp 433-440 (2020)
Background and Aim Non‐alcoholic fatty liver disease (NAFLD) is rapidly becoming the leading indication for liver transplant and is associated with increased cardiovascular and liver mortality, yet there are no licensed therapies. Sodium‐glucose
Externí odkaz:
https://doaj.org/article/e4dd5d2c58194f9b9fc1070e71693d5a
Autor:
Phillip G. Jellyman, Caitlin M. Quilty, Christina R. Thomas, Charlotte B. Green, Michael J. H. Hickford
Publikováno v:
New Zealand Journal of Marine and Freshwater Research. :1-19
Growing demand for water requires resource managers to be innovative to minimise impacts on aquatic ecosystems. There are increasing concerns about fish damage and losses at water intakes, but few studies have examined the effectiveness of different
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd893fa1d519a53df4030149c81860d5
https://doi.org/10.1080/00288330.2023.2173256
https://doi.org/10.1080/00288330.2023.2173256
Autor:
Michael Pavlides, Fredrik Karpe, Leanne Hodson, Charlotte J Green, Camilla Pramfalk, Catriona A Charlton, Pippa J Gunn, Thomas Cornfield
Publikováno v:
BMJ Open Diabetes Research & Care, Vol 8, Iss 1 (2020)
Objective Increased hepatic de novo lipogenesis (DNL) is suggested to be an underlying cause in the development of nonalcoholic fatty liver disease and/or insulin resistance. It is suggested that omega-3 fatty acids (FA) lower hepatic DNL. We investi
Externí odkaz:
https://doaj.org/article/a41b7a35e9714780bb39e6d837c1d121
Autor:
Pippa J. Gunn, Camilla Pramfalk, Val Millar, Thomas Cornfield, Matthew Hutchinson, Elspeth M. Johnson, Shilpa R. Nagarajan, Perla Troncoso‐Rey, Richard F. Mithen, Katherine E. Pinnick, Maria H. Traka, Charlotte J. Green, Leanne Hodson
Publikováno v:
Physiological Reports, Vol 8, Iss 13, Pp n/a-n/a (2020)
Abstract Background and Aims Nonalcoholic fatty liver disease (NAFLD) begins with steatosis, where a mixed macrovesicular pattern of large and small lipid droplets (LDs) develops. Since in vitro models recapitulating this are limited, the aims of thi
Externí odkaz:
https://doaj.org/article/e32076d2d1cd413e9564f974e3446efb
Autor:
Clare E. West, Mohd Karim, Maria J. Falaguera, Leo Speidel, Charlotte J. Green, Lisa Logie, Jeremy Schwartzentruber, David Ochoa, Janet M. Lord, Michael A. J. Ferguson, Chas Bountra, Graeme F. Wilkinson, Beverley Vaughan, Andrew R. Leach, Ian Dunham, Brian D. Marsden
Advancing age is the greatest risk factor for developing multiple age-related diseases. When developing therapeutics, using a Geroscience approach to target the shared underlying pathways of ageing, rather than individual diseases, may be an effectiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::68c1d5c8870320a164e69647c345cc59
https://doi.org/10.1101/2022.11.11.22282236
https://doi.org/10.1101/2022.11.11.22282236
Autor:
De Lin, Charlotte J. Green, Alain-Pierre Petit, David W. Gray, Euan A. F. Fordyce, Victoria H. Cowling, Lesley-Anne Pearson
Publikováno v:
Slas Discovery
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) represents a significant threat to human health. Despite its similarity to related coronaviruses, there are currently no specific treatments for COVID-19 infection, and therefore there is a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7027608aefa24d7689fc44d214c89e8c
https://doi.org/10.1177/24725552211000652
https://doi.org/10.1177/24725552211000652
Autor:
Charlotte J Green, Thomas Marjot, John Walsby-Tickle, Catriona Charlton, Thomas Cornfield, Felix Westcott, Katherine E Pinnick, Ahmad Moolla, Jonathan M Hazlehurst, James McCullagh, Jeremy W Tomlinson, Leanne Hodson
Objective Metformin is a first-line pharmacotherapy in the treatment of type 2 diabetes, a condition closely associated with non-alcoholic fatty liver disease (NAFLD). Although metformin promotes weight loss and improves insulin sensitivity, its effe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e4ae4874c6c19249dd759fceb7e3d27
https://doi.org/10.1530/eje-21-0850
https://doi.org/10.1530/eje-21-0850