Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Charlotte A Stoneham"'
Autor:
Charlotte A Stoneham, Simon Langer, Paul D De Jesus, Jacob M Wozniak, John Lapek, Thomas Deerinck, Andrea Thor, Lars Pache, Sumit K Chanda, David J Gonzalez, Mark Ellisman, John Guatelli
Publikováno v:
PLoS Pathogens, Vol 17, Iss 11, p e1009409 (2021)
The HIV-1 accessory protein Vpu modulates membrane protein trafficking and degradation to provide evasion of immune surveillance. Targets of Vpu include CD4, HLAs, and BST-2. Several cellular pathways co-opted by Vpu have been identified, but the pic
Externí odkaz:
https://doaj.org/article/2522facbcf89469cb6071b09673a1333
Autor:
Sang Ho Park, Haley Siddiqi, Daniela V Castro, Anna A De Angelis, Aaron L Oom, Charlotte A Stoneham, Mary K Lewinski, Alex E Clark, Ben A Croker, Aaron F Carlin, John Guatelli, Stanley J Opella
Publikováno v:
PLoS Pathogens, Vol 17, Iss 5, p e1009519 (2021)
SARS-CoV-2 is the novel coronavirus that is the causative agent of COVID-19, a sometimes-lethal respiratory infection responsible for a world-wide pandemic. The envelope (E) protein, one of four structural proteins encoded in the viral genome, is a 7
Externí odkaz:
https://doaj.org/article/7c6420860ea3475c9217299c1fbe66ce
Autor:
Peter W. Ramirez, Shilpi Sharma, Rajendra Singh, Charlotte A. Stoneham, Thomas Vollbrecht, John Guatelli
Publikováno v:
Cells, Vol 8, Iss 9, p 1020 (2019)
The plasma membrane is a site of conflict between host defenses and many viruses. One aspect of this conflict is the host’s attempt to eliminate infected cells using innate and adaptive cell-mediated immune mechanisms that recognize features of the
Externí odkaz:
https://doaj.org/article/368ca080e556417e9bc3ee8203de7724
Autor:
Kaoutar Bentayebi, Richard L. Sidman, Charlotte A. Stoneham, Supachai Topanurak, Peraphan Pothachareon, Sajee Waramit, Keittisak Suwan, Teerapong Yata, Renata Pasqualini, Paladd Asavarut, Juri G. Gelovani, Justyna Przystal, Wadih Arap, Amin Hajitou, Tracey L. Smith, Aitthiphon Chongchai, Koon-Yang Lee
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, vol 116, iss 37
Bacteriophage (phage) have attractive advantages as delivery systems compared with mammalian viruses, but have been considered poor vectors because they lack evolved strategies to confront and overcome mammalian cell barriers to infective agents. We
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee5bfe9025d12e031bc25fea1f65ca89
https://doi.org/10.1073/pnas.1906653116
https://doi.org/10.1073/pnas.1906653116
Autor:
Mary K. Lewinski, John C. Guatelli, Aaron L. Oom, Charlotte A. Stoneham, Daniela V. Castro, Haley Siddiqi, Ben A. Croker, Stanley J. Opella, Sang Ho Park, Alex E. Clark, Aaron F. Carlin, Anna A. De Angelis
Publikováno v:
PLoS pathogens, vol 17, iss 5
PLoS Pathogens, Vol 17, Iss 5, p e1009519 (2021)
PLoS Pathogens
PLoS Pathogens, Vol 17, Iss 5, p e1009519 (2021)
PLoS Pathogens
SARS-CoV-2 is the novel coronavirus that is the causative agent of COVID-19, a sometimes-lethal respiratory infection responsible for a world-wide pandemic. The envelope (E) protein, one of four structural proteins encoded in the viral genome, is a 7
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09c20489ebca7cc3c7699c09635ede84
https://escholarship.org/uc/item/8jk636qf
https://escholarship.org/uc/item/8jk636qf
Autor:
John C. Guatelli, Charlotte A. Stoneham, Mary K. Lewinski, Aaron L. Oom, Alicia L. Richards, Km Shams-Ud-Doha, Jacob M. Wozniak, David Gonzalez, Nevan J. Krogan
As systems biology approaches to virology have become more tractable, highly studied viruses such as HIV can now be analyzed in new, unbiased ways, including spatial proteomics. We employed here a differential centrifugation protocol to fractionate J
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b43eae77d0170f30a3655183978aaf16
https://doi.org/10.1101/2021.03.17.435902
https://doi.org/10.1101/2021.03.17.435902
Autor:
Aaron L. Oom, Charlotte A. Stoneham, Mary K. Lewinski, Alicia Richards, Jacob M. Wozniak, Km Shams-Ud-Doha, David J. Gonzalez, Nevan J. Krogan, John Guatelli
Publikováno v:
Molecular & cellular proteomics : MCP, vol 21, iss 3
As systems biology approaches to virology have become more tractable, highly studied viruses such as HIV can now be analyzed in new unbiased ways, including spatial proteomics. We employed here a differential centrifugation protocol to fractionate Ju
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1174430a51d17eef41ba136eae4f28be
https://pubmed.ncbi.nlm.nih.gov/35017099
https://pubmed.ncbi.nlm.nih.gov/35017099
Autor:
Christopher Churas, Lisa Miorin, Dexter Pratt, Anshu P. Gounder, Aaron L. Oom, Laura Martin-Sancho, Sumit K. Chanda, Judd F. Hultquist, Sophie Liu, Courtney Nguyen, Max W. Chang, Ariel Rodriguez-Frandsen, Trey Ideker, Alan M. O’Neill, Matthew Urbanowski, Yuan Pu, Megan L. Shaw, Sara Brin Rosenthal, John C. Guatelli, Paul D. De Jesus, Charlotte A. Stoneham, Christopher Benner, Mary K. Lewinski, Matthew B. Frieman, Lars Pache, Adolfo García-Sastre, Xin Yin
Publikováno v:
bioRxiv
A deficient interferon response to SARS-CoV-2 infection has been implicated as a determinant of severe COVID-19. To identify the molecular effectors that govern interferon control of SARS-CoV-2 infection, we conducted a large-scale gain-of-function a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bdb27efac76461cbaf3aeed7ee78337
https://europepmc.org/articles/PMC7536870/
https://europepmc.org/articles/PMC7536870/
Autor:
Peter W. Ramirez, Charlotte A. Stoneham, Aaron O. Angerstein, Thomas Vollbrecht, John C. Guatelli
Publikováno v:
Virology
The host protein SERINC5 inhibits the infectivity of HIV-1 virions in an Env-dependent manner and is counteracted by Nef. The conformation of the Env trimer reportedly correlates with sensitivity to SERINC5. Here, we tested the hypothesis that the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61eb04906cd95dd0bd56a99069cf2884
https://escholarship.org/uc/item/6rd0c821
https://escholarship.org/uc/item/6rd0c821
Autor:
Nevan J. Krogan, Andrej Sali, Marissa Suarez, Robyn M. Kaake, Jacob Kress, Peter W. Ramirez, Yonghwa Kwon, Charlotte A. Stoneham, Xiaofei Jia, Ignacia Echeverria, John C. Guatelli, Rajendra Singh
The HIV-1 Nef protein suppresses multiple immune surveillance mechanisms to promote viral pathogenesis and is an attractive target for the development of novel therapeutics. A key function of Nef is to remove the CD4 receptor from the cell surface by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04cbde504119a8691879cf094572d956