Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Charlotte A Scarff"'
Autor:
Charlotte A Scarff, Rebecca F Thompson, George F J Newlands, Alexander H Jamson, Christopher Kennaway, Vivian J da Silva, Elida M Rabelo, Chun-Feng Song, John Trinick, W David Smith, Stephen P Muench
Publikováno v:
PLoS Pathogens, Vol 16, Iss 4, p e1008465 (2020)
Roundworm parasite infections are a major cause of human and livestock disease worldwide and a threat to global food security. Disease control currently relies on anthelmintic drugs to which roundworms are becoming increasingly resistant. An alternat
Externí odkaz:
https://doaj.org/article/0ff427ede1274c4cb57f1665bf1bf24f
Autor:
Charlotte A. Scarff, Jonas R S Ribeiro, John E. Johnson, Roger Castells-Graells, George P. Lomonossoff, Tatiana Domitrovic, David M. Lawson, Neil A. Ranson, Emma L. Hesketh
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-12 (2021)
Communications biology, vol 4, iss 1
Communications Biology
Communications biology, vol 4, iss 1
Communications Biology
Many virus capsids undergo exquisitely choreographed maturation processes in their host cells to produce infectious virions, and these remain poorly understood. As a tool for studying virus maturation, we transiently expressed the capsid protein of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af915c315ba702f60f14c9b057bc074b
https://doaj.org/article/8e17ddb56f504029911eedd8efcedc8f
https://doaj.org/article/8e17ddb56f504029911eedd8efcedc8f
Autor:
Sean N. McMillan, Charlotte A. Scarff
Publikováno v:
Current opinion in structural biology. 75
Myosins are a superfamily of ATP-driven actin-dependent molecular motors that are responsible for diverse functions from muscle contraction to cell division. The resolution revolution in cryo-EM has enabled characterisation of the interaction of myos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3e511c8feb9eda5bc6204bf7e8e1ca4
https://pubmed.ncbi.nlm.nih.gov/35636003
https://pubmed.ncbi.nlm.nih.gov/35636003
Autor:
Peter J. Knight, David E. Casas-Mao, Glenn Carrington, Joseph M. Chalovich, Neil A. Ranson, Michelle Peckham, Charlotte A. Scarff
Publikováno v:
Nature
Myosin-2 is essential for processes as diverse as cell division and muscle contraction. Dephosphorylation of its regulatory light chain promotes an inactive, ‘shutdown’ state with the filament-forming tail folded onto the two heads1, which preven
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f84b59919a3dfa843c2de0b23d56a345
https://eprints.whiterose.ac.uk/165604/1/Peckham_Main_final.pdf
https://eprints.whiterose.ac.uk/165604/1/Peckham_Main_final.pdf
Autor:
David P. Klebl, Cristina M. Risi, Charlotte A. Scarff, Betty Virok, Frank Sobott, Vitold E. Galkin, Stephen P. Muench, Howard D. White
Publikováno v:
Biophysical Journal. 121:291a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7380b9774e38fcea7dee3fd542f88538
https://doi.org/10.1016/j.bpj.2021.11.1290
https://doi.org/10.1016/j.bpj.2021.11.1290
Autor:
Frank Sobott, Charlotte A. Scarff, David P. Klebl, Matthew G. Iadanza, Howard D. White, Martin Trebbin, Stephen P. Muench, Florian Kopf, Dimitrios Kontziampasis, Diana C. F. Monteiro
Publikováno v:
IUCrJ
IUCrJ, Vol 6, Iss 6, Pp 1024-1031 (2019)
IUCrJ, Vol 6, Iss 6, Pp 1024-1031 (2019)
Time-resolved structural studies are becoming an important tool in understanding biological function. Here we describe a cryo-EM grid freezing device capable of rapidly mixing and plunge freezing grids within 10 ms.
Structural biology generally
Structural biology generally
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6838973b15f1a0cbdde00e890d053c45
https://eprints.whiterose.ac.uk/149427/3/pw5007.pdf
https://eprints.whiterose.ac.uk/149427/3/pw5007.pdf
Autor:
Weston B. Struwe, Konstantinos Thalassinos, Charlotte A. Scarff, James H. Scrivens, Kevin Pagel, Matthew Edgeworth, Max Crispin, David Harvey
Publikováno v:
Journal of Mass Spectrometry. 51:1064-1079
Nitrogen collisional cross sections (CCSs) of hybrid and complex glycans released from the glycoproteins IgG, gp120 (from human immunodeficiency virus), ovalbumin, α1-acid glycoprotein and thyroglobulin were measured with a travelling-wave ion mobil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8bbbc5670dde901f56d097e12e8d5061
https://doi.org/10.1002/jms.3828
https://doi.org/10.1002/jms.3828
Autor:
Konstantinos Thalassinos, Max Crispin, Kevin Pagel, Weston B. Struwe, Charlotte A. Scarff, Matthew Edgeworth, James H. Scrivens, David Harvey
Publikováno v:
Journal of Mass Spectrometry. 51:219-235
The isomeric structure of high-mannose N-glycans can significantly impact biological recognition events. Here, the utility of travelling-wave ion mobility mass spectrometry for isomer separation of high-mannose N-glycans is investigated. Negative ion
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::062b5072d24b741cbab298cabb06926d
https://doi.org/10.1002/jms.3738
https://doi.org/10.1002/jms.3738
Autor:
Glenn Carrington, Marta Giralt-Pujol, Charlotte A. Scarff, Francine Parker, David E. Casas-Mao, Michelle Peckham
Publikováno v:
The FASEB Journal. 34:1-1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::51113f61372a3fc88f492e4cde5dd2fd
https://doi.org/10.1096/fasebj.2020.34.s1.00126
https://doi.org/10.1096/fasebj.2020.34.s1.00126
Publikováno v:
Journal of Visualized Experiments
Negative stain electron microscopy (EM) allows relatively simple and quick observation of macromolecules and macromolecular complexes through the use of contrast enhancing stain reagent. Although limited in resolution to a maximum of ~18 - 20 A, nega
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::069ee1b8a4ef6b6930aed5e5ec319210
https://pubmed.ncbi.nlm.nih.gov/31999689
https://pubmed.ncbi.nlm.nih.gov/31999689