Zobrazeno 1 - 10
of 220
pro vyhledávání: '"Charlotte A, Peterson"'
Autor:
Mary M. McDermott, Christopher R. Martens, Kathryn J. Domanchuk, Dongxue Zhang, Clara B. Peek, Michael H. Criqui, Luigi Ferrucci, Philip Greenland, Jack M. Guralnik, Karen J. Ho, Melina R. Kibbe, Kate Kosmac, Donald Lloyd-Jones, Charlotte A. Peterson, Robert Sufit, Lu Tian, Stephanie Wohlgemuth, Lihui Zhao, Pei Zhu, Christiaan Leeuwenburgh
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-11 (2024)
Abstract People with lower extremity peripheral artery disease (PAD) have increased oxidative stress, impaired mitochondrial activity, and poor walking performance. NAD+ reduces oxidative stress and is an essential cofactor for mitochondrial respirat
Externí odkaz:
https://doaj.org/article/2c373f254eb346318d878694e2b1a44e
Autor:
Kevin A. Murach, Charlotte A. Peterson
Publikováno v:
BMC Biology, Vol 21, Iss 1, Pp 1-4 (2023)
In the last few years, single cell and single nucleus RNA-sequencing technologies have been leveraged in exercised adult skeletal muscle to reveal complex cell type-specific regulation of muscle plasticity. Expanding -omics technology at single cell
Externí odkaz:
https://doaj.org/article/a081ac341d89427ba3d59fddae519655
Autor:
Mary M. McDermott, Christopher R. Martens, Kathryn J. Domanchuk, Dongxue Zhang, Clara B. Peek, Michael H. Criqui, Luigi Ferrucci, Philip Greenland, Jack M. Guralnik, Karen J. Ho, Melina R. Kibbe, Kate Kosmac, Donald Lloyd-Jones, Charlotte A. Peterson, Robert Sufit, Lu Tian, Stephanie Wohlgemuth, Lihui Zhao, Pei Zhu, Christiaan Leeuwenburgh
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/7c4d910226be4ba0bd22cec080a09721
Autor:
Sunil K. Saini, Daniel Pérez‐Cremades, Henry S. Cheng, Kate Kosmac, Charlotte A Peterson, Lingyu Li, Lu Tian, Gengfu Dong, Kevin K. Wu, Brian Bouverat, Stephanie E. Wohlgemuth, Terence Ryan, Robert L. Sufit, Luigi Ferrucci, Mary M. McDermott, Christiaan Leeuwenburgh, Mark W. Feinberg
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 11, Iss 21 (2022)
Background Peripheral artery disease (PAD) is associated with gastrocnemius muscle abnormalities. However, the biological pathways associated with gastrocnemius muscle dysfunction and their associations with progression of PAD are largely unknown. Th
Externí odkaz:
https://doaj.org/article/21587088378c47698ffa4d8ba378fcb0
Autor:
Douglas E. Long, Kate Kosmac, Cory M. Dungan, Marcas M. Bamman, Charlotte A. Peterson, Philip A. Kern
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
Metformin and statins are currently the focus of large clinical trials testing their ability to counter age-associated declines in health, but recent reports suggest that both may negatively affect skeletal muscle response to exercise. However, it ha
Externí odkaz:
https://doaj.org/article/fed91fc4403a44c8b93878421c3c949c
Autor:
Ferdinand Von Walden, Matthew Rea, C. Brooks Mobley, Yvonne Fondufe-Mittendorf, John J. McCarthy, Charlotte A. Peterson, Kevin A. Murach
Publikováno v:
Epigenetics, Vol 15, Iss 11, Pp 1151-1162 (2020)
In addition to multi-nucleated muscle fibres, numerous resident and infiltrating mononuclear cells populate the muscle compartment. As most epigenetic assays in skeletal muscle are conducted on whole tissue homogenates, essentially nothing is known a
Externí odkaz:
https://doaj.org/article/fb0b9f0b52af4ab79fa2fe8f59fd6409
Autor:
Yuan Wen, Davis A. Englund, Bailey D. Peck, Kevin A. Murach, John J. McCarthy, Charlotte A. Peterson
Publikováno v:
iScience, Vol 24, Iss 8, Pp 102838- (2021)
Summary: Skeletal muscle is composed of post-mitotic myofibers that form a syncytium containing hundreds of myonuclei. Using a progressive exercise training model in the mouse and single nucleus RNA-sequencing (snRNA-seq) for high-resolution characte
Externí odkaz:
https://doaj.org/article/943dd826db33413cb54063aae105fce2
Autor:
Luigi Ferrucci, Julián Candia, Ceereena Ubaida-Mohien, Alexey Lyashkov, Nirad Banskota, Christiaan Leeuwenburgh, Stephanie Wohlgemuth, Jack M. Guralnik, Mary Kaileh, Dongxue Zhang, Robert Sufit, Supriyo De, Myriam Gorospe, Rachel Munk, Charlotte A. Peterson, Mary M. McDermott
Publikováno v:
Circulation Research. 132:1428-1443
Background: Few effective therapies exist to improve lower extremity muscle pathology and mobility loss due to peripheral artery disease (PAD), in part because mechanisms associated with functional impairment remain unclear. Methods: To better unders
Autor:
Kevin A. Murach, Bailey D. Peck, Robert A. Policastro, Ivan J. Vechetti, Douglas W. Van Pelt, Cory M. Dungan, Lance T. Denes, Xu Fu, Camille R. Brightwell, Gabriel E. Zentner, Esther E. Dupont-Versteegden, Christopher I. Richards, Jeramiah J. Smith, Christopher S. Fry, John J. McCarthy, Charlotte A. Peterson
Publikováno v:
iScience, Vol 24, Iss 4, Pp 102372- (2021)
Summary: Using in vivo muscle stem cell (satellite cell)-specific extracellular vesicle (EV) tracking, satellite cell depletion, in vitro cell culture, and single-cell RNA sequencing, we show satellite cells communicate with other cells in skeletal m
Externí odkaz:
https://doaj.org/article/bf5d536bcc1c44ae96a88fbbda14f370
Autor:
Melissa L. Erickson, Jacob M. Allen, Daniel P. Beavers, Linda M. Collins, Karina W. Davidson, Kirk I. Erickson, Karyn A. Esser, Matthijs K. C. Hesselink, Kerrie L. Moreau, Eric B. Laber, Charlotte A. Peterson, Courtney M. Peterson, Jane E. Reusch, John P. Thyfault, Shawn D. Youngstedt, Juleen R. Zierath, Bret H. Goodpaster, Nathan K. LeBrasseur, Thomas W. Buford, Lauren M. Sparks
Publikováno v:
Geroscience, 45(1), 569-589. Springer International Publishing
Abstract Exercise is a cornerstone of preventive medicine and a promising strategy to intervene on the biology of aging. Variation in the response to exercise is a widely accepted concept that dates back to the 1980s with classic genetic studies iden