Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Charlotte, Spitz"'
Autor:
Alkmini A. Papadopoulou, Walter Stelzer, Mara Silber, Christine Schlosser, Charlotte Spitz, Martina Haug-Kröper, Tobias Straub, Stephan A. Müller, Stefan F. Lichtenthaler, Claudia Muhle-Goll, Dieter Langosch, Regina Fluhrer
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-18 (2022)
Abstract Signal-Peptide Peptidase Like-3 (SPPL3) is an intramembrane cleaving aspartyl protease that causes secretion of extracellular domains from type-II transmembrane proteins. Numerous Golgi-localized glycosidases and glucosyltransferases have be
Externí odkaz:
https://doaj.org/article/9faad70949594762948f92ade4978291
Autor:
Charlotte Spitz, Christine Schlosser, Nadja Guschtschin-Schmidt, Walter Stelzer, Simon Menig, Alexander Götz, Martina Haug-Kröper, Christina Scharnagl, Dieter Langosch, Claudia Muhle-Goll, Regina Fluhrer
Publikováno v:
iScience, Vol 23, Iss 12, Pp 101775- (2020)
Summary: Ectodomain (EC) shedding defines the proteolytic removal of a membrane protein EC and acts as an important molecular switch in signaling and other cellular processes. Using tumor necrosis factor (TNF)α as a model substrate, we identify a no
Externí odkaz:
https://doaj.org/article/c3b63148f6c64088b959a5bd718b3a1c
Autor:
Günter U. Höglinger, Matthias Brendel, Nils Briel, Sibylle Ziegler, Michael Willem, Charlotte Spitz, Johannes Levin, Maximilian Deussing, Franz-Josef Gildehaus, Thomas Wiedemann, Gloria Biechele, Karin Wind, Jochen Herms, Sabina Tahirovic, Sara Ribicic, Yuan Shi, Tanja Blume, Robert Perneczky, Peter Bartenstein, Carla Palleis, Sven Lammich, Boris-Stephan Rauchmann, Simon Lindner, Artem Zatcepin, Axel Rominger, Karlheinz Baumann, Katharina Buerger, Florian Eckenweber, Alexander Drzezga, Leonie Beyer, Xianyuan Xiang, Gesine Respondek, Nicolai Franzmeier, Christian Haass
Publikováno v:
Science translational medicine 13(615), eabe5640 (2021). doi:10.1126/scitranslmed.abe5640
2-Deoxy-2-[18F]fluoro-d-glucose positron emission tomography (FDG-PET) is widely used to study cerebral glucose metabolism. Here, we investigated whether the FDG-PET signal is directly influenced by microglial glucose uptake in mouse models and patie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a2ed464903b494989f1b31774cb6b23
https://doi.org/10.1126/scitranslmed.abe5640
https://doi.org/10.1126/scitranslmed.abe5640
Autor:
Christian Weber, Petteri Rinne, Esther Lutgens, Angelika Dandl, S. Reim, E. Biessen, Jan Van den Bossche, Linda Beckers, Svenja Meiler, Menno P.J. de Winther, Norbert Gerdes, Dirk Lievens, David Engel, Holger Winkels, Charlotte Spitz, Alexander Faussner, Esther Smeets, Jannie Borst, Christina Bürger, Maiwand Ahmadsei, Martin Schmitt, Remco T. A. Megens, Lesca M. Holdt
Publikováno v:
Thrombosis and Haemostasis, 117(1), 164-175. Schattauer GmbH
Thrombosis and haemostasis, 117(1), 164-175. Schattauer GmbH
Thrombosis and Haemostasis, 117(1), 164-175. Georg Thieme Verlag
Thrombosis and haemostasis, 117(1), 164-175. Schattauer GmbH
Thrombosis and Haemostasis, 117(1), 164-175. Georg Thieme Verlag
SummaryThe costimulatory molecule CD70 is expressed on activated immune cells and is known to modulate responses of T, B, and NK cells via its receptor CD27. Until now, there is only limited data describing the role of CD70 in atherosclerosis. We obs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bad5ce88dea28a7da13a77a56706809
https://doi.org/10.1160/th16-04-0318
https://doi.org/10.1160/th16-04-0318
Regulatory T cells in atherosclerosis: critical immune regulatory function and therapeutic potential
Autor:
Christian Weber, Charlotte Spitz, Norbert Gerdes, Göran K. Hansson, Christina Bürger, Esther Lutgens, Holger Winkels
Publikováno v:
Cellular and molecular life sciences. 73(5):901-922
Atherosclerosis is a chronic inflammatory disease that is mediated by innate and adaptive immune responses. The disease is characterized by sub-endothelial accumulation and modification of lipids in the artery wall triggering an inflammatory reaction
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6573f70b4a95477efb421f4fdf9a5fca
https://doi.org/10.1007/s00018-015-2080-2
https://doi.org/10.1007/s00018-015-2080-2
Autor:
Christian Weber, S. Reim, Norbert Gerdes, Charlotte Spitz, Christina Bürger, Svenja Meiler, Holger Winkels, Esther Lutgens
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 36
Background: Adaptive immunity and co-stimulatory signals are pivotal to all stages of atherosclerosis. CD40-CD40L (CD154) co-stimulatory molecules are central mediators of disease progression. However, it remains undetermined whether platelet- or T c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a170922edd0133ef1aa1946ed436eb2d
https://doi.org/10.1161/atvb.36.suppl_1.240
https://doi.org/10.1161/atvb.36.suppl_1.240
Autor:
Esther Lutgens, S. Reim, Helene Hartwig, Dirk Lievens, Angelika Dandl, Martin Schmitt, Linda Beckers, Alexander Faussner, Christina Bürger, Svenja Meiler, Holger Winkels, Remco T. A. Megens, Jannie Borst, Norbert Gerdes, Maiwand Ahmadsei, Michael Hristov, Charlotte Spitz, Lesca M. Holdt, E. Biessen, Christian Weber, David Engel
Publikováno v:
European Heart Journal
European heart journal, 38(48), 3590-3599. Oxford University Press
European Heart Journal, 38(48), 3590-3599. Oxford University Press
European heart journal, 38(48), 3590-3599. Oxford University Press
European Heart Journal, 38(48), 3590-3599. Oxford University Press
Aims The co-stimulatory receptor CD27 modulates responses of T cells, B cells, and NK cells. Various T cell subsets participate in atherogenesis. However, the role of CD27 in atherosclerosis remains unexplored.Methods and results Here we investigated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9a8113c598cca99bd97de2d51fe54e4
https://pubmed.ncbi.nlm.nih.gov/29182738
https://pubmed.ncbi.nlm.nih.gov/29182738
Autor:
Holger Winkels, Esther Smeets, Svenja Meiler, Linda Beckers, Angelika Dandl, Sigrid Reim, Charlotte Spitz, Christina Bürger, Christian Weber, Esther Lutgens, Norbert Gerdes
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 35
Atherosclerosis, an inflammatory disease of large arteries, is - through its clinical manifestations stroke and myocardial infarction - the leading cause of morbidity and mortality in the industrialized world. Adaptive immunity and co-stimulatory sig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ac189adf69c222ec99b3329b9240bc6f
https://doi.org/10.1161/atvb.35.suppl_1.171
https://doi.org/10.1161/atvb.35.suppl_1.171
Publikováno v:
Dream Interpretation Ancient and Modern: Notes from the Seminar Given in 1936-1941: Notes from the Seminar Given in 1936-1941
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4593b2452b4ffe07f161c6d504804f05
https://doi.org/10.1515/9781400852796-015
https://doi.org/10.1515/9781400852796-015
Autor:
Holger Winkels, Christian Weber, Norbert Gerdes, C. Buerger, Esther Lutgens, Jannie Borst, Charlotte Spitz, Alexander Faussner, Svenja Meiler
Publikováno v:
Atherosclerosis. 252:e262
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::976ada727ee1378c7a46149765614131
https://doi.org/10.1016/j.atherosclerosis.2016.07.095
https://doi.org/10.1016/j.atherosclerosis.2016.07.095