Zobrazeno 1 - 10
of 176
pro vyhledávání: '"Charlotte, Pawlyn"'
Autor:
Charlotte Pawlyn, Fredrik H. Schjesvold, David A. Cairns, L. J. Wei, Faith Davies, Omar Nadeem, Haifaa Abdulhaq, Maria-Victoria Mateos, Jacob Laubach, Katja Weisel, Heinz Ludwig, S. Vincent Rajkumar, Pieter Sonneveld, Graham Jackson, Gareth Morgan, Paul G. Richardson
Publikováno v:
Blood Cancer Journal, Vol 14, Iss 1, Pp 1-8 (2024)
Abstract Measurement of overall survival (OS) remains the gold standard for interpreting the impact of new therapies for multiple myeloma in phase 3 trials. However, as outcomes have improved, it is increasingly challenging to use OS as the primary e
Externí odkaz:
https://doaj.org/article/186d300a7c3d4b47adaec4bd25b20ac5
Autor:
Hira Mian, Arleigh McCurdy, Smith Giri, Shakira Grant, Bram Rochwerg, Erica Winks, Ashley E. Rosko, Monika Engelhardt, Charlotte Pawlyn, Gordon Cook, Graham Jackson, Sara Bringhen, Thierry Facon, Alessandra Larocca, Sonja Zweegman, Tanya M. Wildes
Publikováno v:
Blood Cancer Journal, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract Multiple myeloma (MM) is an incurable blood cancer that primarily affects older adults. Several frailty tools have been developed to address the heterogeneity of aging in this population. Uptake of these measures has been variable, leading t
Externí odkaz:
https://doaj.org/article/076d33876b5743238d8aecfa4776d328
Autor:
Nizar J Bahlis, Suzanne Trudel, Hang Quach, Rakesh Popat, Sagar Lonial, Robert Z Orlowski, Kihyun Kim, Maria-Victoria Mateos, Charlotte Pawlyn, Karthik Ramasamy, Joaquín Martinez-Lopez, Ignacio Casas-Avilés, Alessia Spirli, Jing Gong, Michael Amatangelo, Jessica Katz, Paulo Maciag, Teresa Peluso, Paul Richardson
Publikováno v:
HemaSphere, Vol 7, p e7140563 (2023)
Externí odkaz:
https://doaj.org/article/522fed977a5842e09425448653d3172e
Autor:
Emma Searle, Jim Cavet, Steven Knapper, Ceri Bygrave, Victoria Campbell, Dima El-Sharkawi, Charlotte Pawlyn, Maria Creignou, Harriet S. Walter, David Valcarcel, Marta Hidalgo, Tomasz Knurowski, Karen Clegg, Neil Pegg, Will West, Debbie Haynes, Kris Frese, Tim C. P. Somervaille
Publikováno v:
HemaSphere, Vol 7, p e54143bc (2023)
Externí odkaz:
https://doaj.org/article/80af1a2cc63e462baf94df63306522f8
Autor:
Philippe Moreau, Niels W.C.J. van de Donk, Michel Delforge, Hermann Einsele, Valerio De Stefano, Aurore Perrot, Britta Besemer, Charlotte Pawlyn, Lionel Karlin, Salomon Manier, Xavier Leleu, Pushpike Thilakarathne, Joris Diels, Katharine Gries, Nichola Erler-Yates, Kirsten van Nimwegen, Raúl Morano, Vadim Strulev, Imene Haddad, Rachel Kobos, Jennifer Smit, Alexander Marshall, Mary Slavcev, Maria-Victoria Mateos, Katja Weisel
Publikováno v:
HemaSphere, Vol 7, p e690758f (2023)
Externí odkaz:
https://doaj.org/article/97b316a99d6e4ece8fd097583e08a4c3
Autor:
John R. Jones, David A. Cairns, Tom Menzies, Charlotte Pawlyn, Faith E. Davies, Rachel Sigsworth, Annamaria Brioli, Matthew W. Jenner, Martin F. Kaiser, Catherine Olivier, Molly Reed, Mark T. Drayson, Roger G. Owen, Kevin D. Boyd, Gordon Cook, Gareth J. Morgan, Graham H. Jackson
Publikováno v:
EClinicalMedicine, Vol 62, Iss , Pp 102099- (2023)
Summary: Background: Early trials of long-term lenalidomide use reported an increased incidence of second primary malignancy (SPM), including acute myeloid leukaemia and myelodysplastic syndrome. Later, meta-analysis suggested the link to be secondar
Externí odkaz:
https://doaj.org/article/7b401565bf86409c8aca965e1f509a9d
Autor:
Aikaterini Panopoulou, Sandra Easdale, Mark Ethell, Emma Nicholson, Mike Potter, Asterios Giotas, Helena Woods, Tracy Thornton, Charlotte Pawlyn, Kevin D. Boyd, Martin F. Kaiser
Publikováno v:
HemaSphere, Vol 7, Iss 2, p e831 (2023)
Refined prediction of early relapse following standard-of-care (SoC) autologous stem cell transplant (ASCT) in newly diagnosed multiple myeloma (NDMM) could inform real-world risk-stratified post-ASCT strategies. We investigated the impact of double
Externí odkaz:
https://doaj.org/article/6e2bc5ac2d034cf78e663d2ca195209b
Autor:
Roger Owen, John Jones, David Meads, David A Cairns, Christopher Parrish, Gordon Cook, Neil Rabin, Matthew Jenner, Martin Kaiser, Kevin Boyd, Graham Jackson, Catherine Olivier, Amy Beth Coulson, Kara-Louise Royle, Charlotte Pawlyn, Anna Hockaday, Jennifer Bird, Stella Bowcock, Ruth de Tute, Hayley Gardner, Bryony Dawkins, Rowena Henderson, Phillip Best, Bhuvan Kishore, Mark Drayson
Publikováno v:
BMJ Open, Vol 12, Iss 6 (2022)
Externí odkaz:
https://doaj.org/article/3d2818c0a21d4f5daf3843685e054b9c
Autor:
Graham H Jackson, Charlotte Pawlyn, David A Cairns, Ruth M de Tute, Anna Hockaday, Corinne Collett, John R Jones, Bhuvan Kishore, Mamta Garg, Cathy D Williams, Kamaraj Karunanithi, Jindriska Lindsay, Alberto Rocci, John A Snowden, Matthew W Jenner, Gordon Cook, Nigel H Russell, Mark T Drayson, Walter M Gregory, Martin F Kaiser, Roger G Owen, Faith E Davies, Gareth J Morgan, UK NCRI Haemato-oncology Clinical Studies Group
Publikováno v:
PLoS Medicine, Vol 18, Iss 1, p e1003454 (2021)
BackgroundCarfilzomib is a second-generation irreversible proteasome inhibitor that is efficacious in the treatment of myeloma and carries less risk of peripheral neuropathy than first-generation proteasome inhibitors, making it more amenable to comb
Externí odkaz:
https://doaj.org/article/7fe445c9d7494b4397c8fa9d9a9d2182
Autor:
Charlotte Pawlyn, David Cairns, Tom Menzies, John Jones, Matthew Jenner, Gordon Cook, Kevin Boyd, Mark Drayson, Martin Kaiser, Roger Owen, Walter Gregory, Gareth Morgan, Graham Jackson, Faith Davies
Publikováno v:
Haematologica, Vol 107, Iss 1 (2020)
Autologous stem cell transplant (ASCT) remains the standard of care for consolidation after induction therapy for eligible patients with newly diagnosed myeloma. In recent clinical trials comparing ASCT to delayed ASCT, patients aged over 65 were exc
Externí odkaz:
https://doaj.org/article/8df70886a81d4741a12b4dac21259320