Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Charlotte, Bold"'
Autor:
Charlotte Bold, Ulrike Müller, Kristin Metzdorf, Kristin Michaelsen-Preusse, Martin Korte, Susann Ludewig, Jennifer Just, Ulrike Herrmann
Publikováno v:
Proc Natl Acad Sci U S A
Alterations in Ca(2+) homeostasis have been reported in several in vitro and in vivo studies using mice expressing the Alzheimer’s disease–associated transgenes, presenilin and the amyloid precursor protein (APP). While intense research focused o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f6248f8e1fc4b0d3c75de589a59706b
https://doi.org/10.1073/pnas.2011506118
https://doi.org/10.1073/pnas.2011506118
Autor:
Roman Spilger, Susann Ludewig, Charlotte Bold, Karl Rohr, Danny Baltissen, Ulrike Müller, Martin Korte
A large body of evidence indicates a neuroprotective and neurotrophic function for APPs⍺ not only in vitro, but also when expressed by AAV vectors in vivo such as in APP/PS1 transgenic AD model mice with Aβ-induced pathology. Previously, we could
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d42eb0f5b826ff96a5902d6b4f807754
https://doi.org/10.14293/s2199-1006.1.sor-.ppa6v3n.v1
https://doi.org/10.14293/s2199-1006.1.sor-.ppa6v3n.v1
Autor:
Stefan F. Lichtenthaler, Thomas Deller, Meike Fellenz, Charlotte Bold, Denise Becker, Andreas Vlachos, Ulrike Müller, Christos Galanis
Publikováno v:
The Journal of Neuroscience
The journal of neuroscience 41(24), 5157-5172 (2021). doi:10.1523/JNEUROSCI.1820-20.2021
The journal of neuroscience 41(24), 5157-5172 (2021). doi:10.1523/JNEUROSCI.1820-20.2021
The physiological role of the amyloid-precursor protein (APP) is insufficiently understood. Recent work has implicated APP in the regulation of synaptic plasticity. Substantial evidence exists for a role of APP and its secreted ectodomain APPsα in H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::166a71f15ebe5d9a5fc57337675f2121
https://doi.org/10.1101/2020.06.22.152066
https://doi.org/10.1101/2020.06.22.152066
Autor:
Christine R. Rose, Vanessa Augustin, Christian Steinhäuser, Julia Langer, Dennis J. Weingarten, Camille Philippot, Simon L. Wadle, Charlotte Bold, Jonathan Stephan, Ronald Jabs
Publikováno v:
Glia. 64:1892-1911
Astrocytes form large gap junctional networks that contribute to ion and neurotransmitter homeostasis. Astrocytes concentrate in the lateral superior olive (LSO), a prominent auditory brainstem center. Compared to the LSO, astrocyte density is lower
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::34f3745952f56826e4b8331d66b1ba28
https://doi.org/10.1002/glia.23031
https://doi.org/10.1002/glia.23031
Autor:
Charlotte Bold, Susanne Klein, Kang Han, Alex Winschel, Max Richter, Leonie R Salzburger, Susann Ludewig, Ulrike Müller, Sascha W. Weyer, Christian J. Buchholz, Tobias Abel, Ann-Kristina Fritz, Bodo Laube, Martin Korte, David P. Wolfer
Publikováno v:
The EMBO Journal. 37
Increasing evidence suggests that synaptic functions of the amyloid precursor protein (APP), which is key to Alzheimer pathogenesis, may be carried out by its secreted ectodomain (APPs). The specific roles of APPsα and APPsβ fragments, generated by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::926fba1a3a6fe53557e48ebe0338367e
https://doi.org/10.15252/embj.201798335
https://doi.org/10.15252/embj.201798335
Autor:
Max C, Richter, Susann, Ludewig, Alex, Winschel, Tobias, Abel, Charlotte, Bold, Leonie R, Salzburger, Susanne, Klein, Kang, Han, Sascha W, Weyer, Ann-Kristina, Fritz, Bodo, Laube, David P, Wolfer, Christian J, Buchholz, Martin, Korte, Ulrike C, Müller
Publikováno v:
The EMBO journal. 37(11)
Increasing evidence suggests that synaptic functions of the amyloid precursor protein (APP), which is key to Alzheimer pathogenesis, may be carried out by its secreted ectodomain (APPs). The specific roles of APPsα and APPsβ fragments, generated by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9c15583dc66cb226e9d0602fb5a68a32
https://pubmed.ncbi.nlm.nih.gov/29661886
https://pubmed.ncbi.nlm.nih.gov/29661886
Autor:
Vanessa, Augustin, Charlotte, Bold, Simon L, Wadle, Julia, Langer, Ronald, Jabs, Camille, Philippot, Dennis J, Weingarten, Christine R, Rose, Christian, Steinhäuser, Jonathan, Stephan
Publikováno v:
Glia. 64(11)
Astrocytes form large gap junctional networks that contribute to ion and neurotransmitter homeostasis. Astrocytes concentrate in the lateral superior olive (LSO), a prominent auditory brainstem center. Compared to the LSO, astrocyte density is lower
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::458c964c0f0a3602e1912b323528d810
https://pubmed.ncbi.nlm.nih.gov/27458984
https://pubmed.ncbi.nlm.nih.gov/27458984