Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Charlotta Sundin"'
Publikováno v:
Biomolecules, Vol 11, Iss 1, p 55 (2021)
Pseudomonas aeruginosa is an opportunistic bacterial pathogen that employs its type III secretion system (T3SS) during the acute phase of infection to translocate cytotoxins into the host cell cytoplasm to evade the immune system. The PcrV protein is
Externí odkaz:
https://doaj.org/article/d7c9736cc12441e79098053d35072517
Autor:
Caroline E Zetterström, Jenny Hasselgren, Olli Salin, Rohan A Davis, Ronald J Quinn, Charlotta Sundin, Mikael Elofsson
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e81969 (2013)
Society faces huge challenges, as a large number of bacteria have developed resistance towards many or all of the antibiotics currently available. Novel strategies that can help solve this problem are urgently needed. One such strategy is to target b
Externí odkaz:
https://doaj.org/article/2818f80a2b4c4cb48cf9cd6861b541ca
Autor:
Christer Larsson, Charlotta Sundin, Ramesh Ummanni, Hasan Tükenmez, Mikael Elofsson, Stina Berglund Fick, Isabel Edström
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-9 (2019)
Scientific Reports
Scientific Reports
High-throughput screening facilities do not generally support biosafety level 3 organisms such as Mycobacterium tuberculosis. To discover not only antibacterials, but also virulence inhibitors with either bacterial or host cell targets, an assay moni
Publikováno v:
Biomolecules
Volume 11
Issue 1
Biomolecules, Vol 11, Iss 55, p 55 (2021)
Volume 11
Issue 1
Biomolecules, Vol 11, Iss 55, p 55 (2021)
Pseudomonas aeruginosa is an opportunistic bacterial pathogen that employs its type III secretion system (T3SS) during the acute phase of infection to translocate cytotoxins into the host cell cytoplasm to evade the immune system. The PcrV protein is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef387b4608153286e8fa178222374567
http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-150969
http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-150969
Publikováno v:
Biomolecules
Pseudomonas aeruginosa is an opportunistic bacterial pathogen that employs its type III secretion system (T3SS) during the acute phase of infection to translocate cytotoxins into the host cell cytoplasm to evade the immune system. The PcrV protein is
Autor:
Mikael Elofsson, Charlotta Sundin, Robert Brkljača, Sylvia Urban, Duc Duy Vo, Caroline E. Zetterström
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Scientific Reports
Scientific Reports
Bacterial infections continue to threaten humankind and the rapid spread of antibiotic resistant bacteria is alarming. Current antibiotics target essential bacterial processes and thereby apply a strong selective pressure on pathogenic and non-pathog
Autor:
Charlotta Sundin, Sadaf Kalsum, Stina Berglund Fick, Maria Lerm, Isabel Edström, Christer Larsson, Mikael Elofsson, Hasan Tükenmez, Clara Braian, Ramesh Ummanni
The effect of corticosteroids on human physiology is complex and their use in tuberculosis patients remains controversial. In a high-throughput screening approach designed to discover virulence inhibitors, several corticosteroids were found to preven
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2d58a7c175a3e9b2aec4d699ebdd06b
http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-157508
http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-157508
Autor:
Åke Forsberg, Mahsa Ebrahimi, Herwig Schüler, A.F. Pinto, Mikael Elofsson, Charlotta Sundin, Michael Saleeb, Öznur Aglar
During infection, the Gram-negative opportunistic pathogen Pseudomonas aeruginosa employs its type III secretion system to translocate the toxin exoenzyme S (ExoS) into the eukaryotic host cell cytoplasm. ExoS is an essential in vivo virulence factor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db8ec45f6d5e924838118a18fde63db4
http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-143429
http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-143429
Autor:
Mikael Elofsson, Ulrik Hägglund, Charlotta Sundin, Henrik Scherman Norberg, Pia Uusitalo, Elin Rhöös
Publikováno v:
The Journal of antibiotics. 70(9)
Pseudomonas aeruginosa is an opportunistic pathogen that can be very hard to treat because of high resistance to different antibiotics and alternative treatment regimens are greatly needed. An alternative or a complement to traditional antibiotic is
Autor:
Julien M. Buyck, Paul M. Tulkens, Charlotta Sundin, Ahalieyah Anantharajah, Françoise Van Bambeke, Marie-Paule Mingeot-Leclercq
Publikováno v:
Antimicrobial Agents and Chemotherapy, Vol. 61, no. 6 (2017), p. e02566-16 (2017)
Antimicrobial Agents and Chemotherapy
Antimicrobial Agents and Chemotherapy, American Society for Microbiology, 2017, 61 (6), pp.515.e1-515.e4. ⟨10.1128/AAC.02566-16⟩
Antimicrobial Agents and Chemotherapy
Antimicrobial Agents and Chemotherapy, American Society for Microbiology, 2017, 61 (6), pp.515.e1-515.e4. ⟨10.1128/AAC.02566-16⟩
Type 3 secretion systems (T3SSs) are major virulence factors in Gram-negative bacteria. Pseudomonas aeruginosa expresses two T3SSs, namely, an injectisome (iT3SS) translocating effector proteins in the host cell cytosol and a flagellum (fT3SS) ensuri