Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Charlotta, Böiers"'
Concurrent stem- and lineage-affiliated chromatin programs precede hematopoietic lineage restriction
Autor:
Fatemeh Safi, Parashar Dhapola, Sarah Warsi, Mikael Sommarin, Eva Erlandsson, Jonas Ungerbäck, Rebecca Warfvinge, Ewa Sitnicka, David Bryder, Charlotta Böiers, Ram Krishna Thakur, Göran Karlsson
Publikováno v:
Cell Reports, Vol 42, Iss 10, Pp 113357- (2023)
Externí odkaz:
https://doaj.org/article/afa99b9a000946b79b1053681bd6ceed
In vitro clonal multilineage differentiation of distinct murine hematopoietic progenitor populations
Autor:
Fatemeh Safi, Parashar Dhapola, Eva Erlandsson, Linda Geironson Ulfsson, Ariana S. Calderón, Charlotta Böiers, Göran Karlsson
Publikováno v:
STAR Protocols, Vol 4, Iss 1, Pp 101965- (2023)
Summary: Here we describe an in vitro co-culture system that can differentiate hematopoietic progenitor populations to all major hematopoietic lineages at clonal level. We present both a sensitive single-cell switch-culture system as well as a less l
Externí odkaz:
https://doaj.org/article/5c57f55d5800494682503c01d97127a2
Autor:
Dylan Stavish, Charlotta Böiers, Christopher Price, Thomas J. R. Frith, Jason Halliwell, Ingrid Saldaña-Guerrero, Jason Wray, John Brown, Jonathon Carr, Chela James, Ivana Barbaric, Peter W. Andrews, Tariq Enver
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
Application of pluripotent cells in regenerative medicine requires an understanding of how they exit pluripotency. Here the authors demonstrate support for the idea that pluripotency exit involves pluripotent intermediates that exhibit lineage bias b
Externí odkaz:
https://doaj.org/article/49cf589d5cb741e6a087de76d2e33465
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Externí odkaz:
https://doaj.org/article/a78eeb4195f54ac9aa11d56ec7a66952
In vitro differentiation of human pluripotent stem cells into the B lineage using OP9-MS5 co-culture
Publikováno v:
STAR Protocols, Vol 2, Iss 2, Pp 100420- (2021)
Summary: In vitro differentiation of human pluripotent stem cells (hPSCs) offers a genetically tractable system to examine the physiology and pathology of human tissue development and differentiation. We have used this approach to model the earliest
Externí odkaz:
https://doaj.org/article/a918438e9d6f4dd4af6e4015bae93202
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Developmental hematopoiesis differs from adult and is far less described. In the developing embryo, waves of lineage-restricted blood precede the ultimate emergence of definitive hematopoietic stem cells (dHSCs) capable of maintaining hematopoiesis t
Externí odkaz:
https://doaj.org/article/f1bcc44b05aa4e3e9226951779604773
Autor:
Carolina Guibentif, Roger Emanuel Rönn, Charlotta Böiers, Stefan Lang, Shobhit Saxena, Shamit Soneji, Tariq Enver, Göran Karlsson, Niels-Bjarne Woods
Publikováno v:
Cell Reports, Vol 19, Iss 1, Pp 10-19 (2017)
During development, hematopoietic cells originate from endothelium in a process known as endothelial-to-hematopoietic transition (EHT). To study human EHT, we coupled flow cytometry and single-cell transcriptional analyses of human pluripotent stem c
Externí odkaz:
https://doaj.org/article/19996555f2b6471a8747518573d65125
Autor:
Jonathon Carr, Jason Wray, Chela James, Christopher J. Price, Jason A. Halliwell, Charlotta Böiers, Tariq Enver, John Brown, Dylan Stavish, Thomas J. R. Frith, Peter W. Andrews, Ivana Barbaric, Ingrid Saldaña-Guerrero
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
Nature Communications
Nature Communications
We postulate that exit from pluripotency involves intermediates that retain pluripotency while simultaneously exhibiting lineage-bias. Using a MIXL1 reporter, we explore mesoderm lineage-bias within the human pluripotent stem cell compartment. We ide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::783bae19c509210a5f4e00479a6b2065
https://doaj.org/article/49cf589d5cb741e6a087de76d2e33465
https://doaj.org/article/49cf589d5cb741e6a087de76d2e33465
Autor:
Mikael N.E. Sommarin, Rasmus Olofzon, Sara Palo, Parashar Dhapola, Göran Karlsson, Charlotta Böiers
Knowledge of human fetal blood development and how it differs from adult is highly relevant for our understanding of congenital blood and immune disorders as well as childhood leukemia, the latter known to originate in utero. Blood production during
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::849fce65876de3f6c26cb96ed2bf43e7
https://doi.org/10.1101/2021.12.29.474425
https://doi.org/10.1101/2021.12.29.474425
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b49232f1383232e5159c28ff102c293
https://www.frontiersin.org/articles/10.3389/fcell.2021.732649/full
https://www.frontiersin.org/articles/10.3389/fcell.2021.732649/full