Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Charlie T. Beales"'
Autor:
Christopher A. Odhams, Amy L. Roberts, Susan K. Vester, Carolina S. T. Duarte, Charlie T. Beales, Alexander J. Clarke, Sonja Lindinger, Samuel J. Daffern, Antonino Zito, Lingyan Chen, Leonardo L. Jones, Lora Boteva, David L. Morris, Kerrin S. Small, Michelle M. A. Fernando, Deborah S. Cunninghame Graham, Timothy J. Vyse
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
Systemic lupus erythematosus (SLE) shows a striking bias towards higher prevalence in females. Here, the authors perform fine-mapping of an SLE-associated locus at Xp21.2 and characterise a candidate gene, CXorf21, as IFN-responsive in immune cells t
Externí odkaz:
https://doaj.org/article/26e43468667241ccb8271a65e26175aa
Autor:
Duaa O. Khair, Heather J. Bax, Silvia Mele, Silvia Crescioli, Giulia Pellizzari, Atousa Khiabany, Mano Nakamura, Robert J. Harris, Elise French, Ricarda M. Hoffmann, Iwan P. Williams, Anthony Cheung, Benjamin Thair, Charlie T. Beales, Emma Touizer, Adrian W. Signell, Nahrin L. Tasnova, James F. Spicer, Debra H. Josephs, Jenny L. Geh, Alastair MacKenzie Ross, Ciaran Healy, Sophie Papa, Katie E. Lacy, Sophia N. Karagiannis
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
The immune system employs several checkpoint pathways to regulate responses, maintain homeostasis and prevent self-reactivity and autoimmunity. Tumor cells can hijack these protective mechanisms to enable immune escape, cancer survival and proliferat
Externí odkaz:
https://doaj.org/article/b0ae52ae6a4746d783b3011fbf5f7d7e
Autor:
Rajaa Boujemaa-Paterski, Bruno Martins, Matthias Eibauer, Charlie T Beales, Benjamin Geiger, Ohad Medalia
Publikováno v:
eLife, Vol 9 (2020)
Vinculin plays a fundamental role in integrin-mediated cell adhesion. Activated by talin, it interacts with diverse adhesome components, enabling mechanical coupling between the actin cytoskeleton and the extracellular matrix. Here we studied the int
Externí odkaz:
https://doaj.org/article/d97526193c804b5e8a669ad98082ffee
Autor:
Matthias Eibauer, Miriam S. Weber, Rafael Kronenberg-Tenga, Charlie T. Beales, Rajaa Boujemaa-Paterski, Yagmur Turgay, Suganya Sivagurunathan, Julia Kraxner, Sarah Köster, Robert D. Goldman, Ohad Medalia
Intermediate filaments (IFs) are integral components of the cytoskeleton. They provide cells with tissue-specific mechanical properties and are involved in numerous cellular processes. Due to their intricate architecture, a 3D structure of IFs has re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f27facfe55c9c83595e105cf213e5dd1
https://doi.org/10.1101/2023.05.22.541714
https://doi.org/10.1101/2023.05.22.541714
Autor:
Jan-Michael Peters, Wen Tang, Christoph C. H. Langer, Stefan L. Ameres, Catherina Gasser, Gregor Jessberger, Eva Neuner, Daniel W. Gerlich, Ronald Micura, Zsuzsanna Takacs, Anton Goloborodko, Charlie T. Beales, Michael Mitter
Publikováno v:
Nature
The three-dimensional organization of the genome supports regulated gene expression, recombination, DNA repair, and chromosome segregation during mitosis. Chromosome conformation capture (Hi-C)1,2 analysis has revealed a complex genomic landscape of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcb532931de43a53be7a48f6e0edfd7e
https://doi.org/10.1038/s41586-020-2744-4
https://doi.org/10.1038/s41586-020-2744-4
Autor:
Jan-Michael Peters, Eva Neuner, Daniel W. Gerlich, Wen Tang, Zsuzsanna Takacs, Catherina Gasser, Gregor Jessberger, Ronald Micura, Christoph C. H. Langer, Anton Goloborodko, Stefan L. Ameres, Charlie T. Beales, Michael Mitter
The three-dimensional organization of the genome supports regulated gene expression, recombination, DNA repair, and chromosome segregation during mitosis. Chromosome conformation capture (Hi-C)1–3 has revealed a complex genomic landscape of interna
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::753ffc370421612067e0ac8623b45868
https://doi.org/10.1101/2020.03.10.978148
https://doi.org/10.1101/2020.03.10.978148
Author response: Talin-activated vinculin interacts with branched actin networks to initiate bundles
Autor:
Ohad Medalia, Matthias Eibauer, Charlie T Beales, Bruno Martins, Benjamin Geiger, Rajaa Boujemaa-Paterski
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c24a1564a207f51f6bd097162ce44ac9
https://doi.org/10.7554/elife.53990.sa2
https://doi.org/10.7554/elife.53990.sa2
Autor:
Duaa O, Khair, Heather J, Bax, Silvia, Mele, Silvia, Crescioli, Giulia, Pellizzari, Atousa, Khiabany, Mano, Nakamura, Robert J, Harris, Elise, French, Ricarda M, Hoffmann, Iwan P, Williams, Anthony, Cheung, Benjamin, Thair, Charlie T, Beales, Emma, Touizer, Adrian W, Signell, Nahrin L, Tasnova, James F, Spicer, Debra H, Josephs, Jenny L, Geh, Alastair, MacKenzie Ross, Ciaran, Healy, Sophie, Papa, Katie E, Lacy, Sophia N, Karagiannis
Publikováno v:
Khair, D O, Bax, H J, Mele, S, Crescioli, S, Pellizzari, G, Khiabany, A, Nakamura, M, Harris, R J, French, E, Hoffmann, R M, Williams, I P, Cheung, K K A, Thair, B, Beales, C T, Touizer, E, Signell, A W, Tasnova, N L, Spicer, J F, Josephs, D H, Geh, J L C, MacKenzie Ross, A, Healy, C, Papa, S E, Lacy, K E & Karagiannis, S N 2019, ' Combining Immune Checkpoint Inhibitors: Established and Emerging Targets and Strategies to Improve Outcomes in Melanoma ', Frontiers in Immunology, no. MAR, 453 . https://doi.org/10.3389/fimmu.2019.00453
Frontiers in Immunology
Frontiers in Immunology
The immune system employs several checkpoint pathways to regulate responses, maintain homeostasis and prevent self-reactivity and autoimmunity. Tumor cells can hijack these protective mechanisms to enable immune escape, cancer survival and proliferat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::6a105eb2a223f32d9f535b0a71fd7e0a
https://kclpure.kcl.ac.uk/en/publications/e8c5d421-3b0c-4218-a0ee-cb661eb30f6e
https://kclpure.kcl.ac.uk/en/publications/e8c5d421-3b0c-4218-a0ee-cb661eb30f6e
Autor:
Christopher A, Odhams, Amy L, Roberts, Susan K, Vester, Carolina S T, Duarte, Charlie T, Beales, Alexander J, Clarke, Sonja, Lindinger, Samuel J, Daffern, Antonino, Zito, Lingyan, Chen, Leonardo L, Jones, Lora, Boteva, David L, Morris, Kerrin S, Small, Michelle M A, Fernando, Deborah S, Cunninghame Graham, Timothy J, Vyse
Publikováno v:
Nature Communications
Systemic lupus erythematosus (SLE) is an autoimmune disease, characterised by increased expression of type I interferon (IFN)-regulated genes and a striking sex imbalance towards females. Through combined genetic, in silico, in vitro, and ex vivo app
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b48291f06a2f99c7938a2b63e9c6bb01
https://pubmed.ncbi.nlm.nih.gov/31092820
https://pubmed.ncbi.nlm.nih.gov/31092820