Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Charlie J Clark"'
Autor:
Chiara Auwerx, Maarja Jõeloo, Marie C. Sadler, Nicolò Tesio, Sven Ojavee, Charlie J. Clark, Reedik Mägi, Estonian Biobank Research Team, Alexandre Reymond, Zoltán Kutalik
Publikováno v:
Genome Medicine, Vol 16, Iss 1, Pp 1-24 (2024)
Abstract Background Copy-number variations (CNVs) have been associated with rare and debilitating genomic disorders (GDs) but their impact on health later in life in the general population remains poorly described. Methods Assessing four modes of CNV
Externí odkaz:
https://doaj.org/article/99204a983c254d6594fd32cb0289dd83
Publikováno v:
Clark, C J, Scott-Brown, J & Gorochowski, T E 2021, ' paraSBOLv : a foundation for standard-compliant genetic design visualization tools ', Synthetic Biology, vol. 6, no. 1, ysab022 . https://doi.org/10.1093/synbio/ysab022
Synthetic Biology
Synthetic Biology
Diagrams constructed from standardized glyphs are central to communicating complex design information in many engineering fields. For example, circuit diagrams are commonplace in electronics and allow for a suitable abstraction of the physical system
Publikováno v:
PLoS Biology, Vol 16, Iss 10, p e3000022 (2018)
This Formal Comment responds to Jordan et al., and stresses that if scientific findings are to be robust, training in experimental design and statistics is critical to ensure that research questions, design considerations, and analyses are aligned.
Externí odkaz:
https://doaj.org/article/5a7cfa68490843f9b6cb7f80cc57591f
Publikováno v:
PLoS Biology, Vol 16, Iss 4, p e2005282 (2018)
Biologists determine experimental effects by perturbing biological entities or units. When done appropriately, independent replication of the entity-intervention pair contributes to the sample size (N) and forms the basis of statistical inference. If
Externí odkaz:
https://doaj.org/article/3e8147c8297e4332b1e26c43b82229be
Autor:
Serena Vales, Jhanna Kryukova, Soumyanetra Chandra, Gintare Smagurauskaite, Megan Payne, Charlie J. Clark, Katrin Hafner, Philomena Mburu, Stepan Denisov, Graham Davies, Carlos Outeiral, Charlotte M. Deane, Garrett M. Morris, Shoumo Bhattacharya
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract CC and CXC-chemokines are the primary drivers of chemotaxis in inflammation, but chemokine network redundancy thwarts pharmacological intervention. Tick evasins promiscuously bind CC and CXC-chemokines, overcoming redundancy. Here we show th
Externí odkaz:
https://doaj.org/article/4d4b476ec059431cbb9a7a4c796377b7