Zobrazeno 1 - 10
of 74
pro vyhledávání: '"Charlie E. M. Strauss"'
Autor:
Heung-Bok Kim, John-Paul Bacik, Ruilian Wu, Ramesh K Jha, Michaeline Hebron, Catherine Triandafillou, Joseph E McCown, Nam-In Baek, Jeong Han Kim, Young Jae Kim, Celia W Goulding, Charlie E M Strauss, Jurgen G Schmidt, Gauri S Shetye, Sungweon Ryoo, Eun-Kyeong Jo, Young Ho Jeon, Li-Wei Hung, Thomas C Terwilliger, Chang-Yub Kim
Publikováno v:
PLoS ONE, Vol 17, Iss 11, p e0277670 (2022)
The ability of Mycobacterium tuberculosis (Mtb) to persist in its host may enable an evolutionary advantage for drug resistant variants to emerge. A potential strategy to prevent persistence and gain drug efficacy is to directly target the activity o
Externí odkaz:
https://doaj.org/article/e919c5aa126347f3a5b5b38c338f2953
Autor:
Julia Koehler Leman, Brian D Weitzner, P Douglas Renfrew, Steven M Lewis, Rocco Moretti, Andrew M Watkins, Vikram Khipple Mulligan, Sergey Lyskov, Jared Adolf-Bryfogle, Jason W Labonte, Justyna Krys, RosettaCommons Consortium, Christopher Bystroff, William Schief, Dominik Gront, Ora Schueler-Furman, David Baker, Philip Bradley, Roland Dunbrack, Tanja Kortemme, Andrew Leaver-Fay, Charlie E M Strauss, Jens Meiler, Brian Kuhlman, Jeffrey J Gray, Richard Bonneau
Publikováno v:
PLoS Computational Biology, Vol 16, Iss 5, p e1007507 (2020)
Many scientific disciplines rely on computational methods for data analysis, model generation, and prediction. Implementing these methods is often accomplished by researchers with domain expertise but without formal training in software engineering o
Externí odkaz:
https://doaj.org/article/39b3fd5bfd834abfb5347fc6af6789bc
Autor:
Shounak Banerjee, Yury Minko, Elizabeth S Anaya, Zachary J Sasiene, Jurgen G Schmidt, Charlie E M Strauss, Geoffrey S Waldo
Measuring the entropic properties of polymers such as proteins is critical to accurate prediction of their functional properties. However, the measurement of configurational entropy is possible only by low throughput techniques such as calorimetry, N
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cbd76e95d847e6546d1f741392d6fced
https://doi.org/10.1101/2022.11.07.515508
https://doi.org/10.1101/2022.11.07.515508
Autor:
Tymor Hamamsy, James T. Morton, Daniel Berenberg, Nicholas Carriero, Vladimir Gligorijevic, Robert Blackwell, Charlie E. M. Strauss, Julia Koehler Leman, Kyunghyun Cho, Richard Bonneau
Exploiting sequence-structure-function relationships in molecular biology and computational modeling relies on detecting proteins with high sequence similarities. However, the most commonly used sequence alignment-based methods, such as BLAST, freque
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7f91da6ea7a9be45d58b2d1e147e67db
https://doi.org/10.1101/2022.07.25.501437
https://doi.org/10.1101/2022.07.25.501437
Autor:
Robert D. Gilbertson, Jurgen G. Schmidt, Jennifer S. Martinez, Ryszard Michalczyk, Jacob C. Miner, M. Lisa Phipps, Trideep Rajale, Charlie E. M. Strauss, Robert F. Williams
Publikováno v:
Chemical Communications. 57:9922-9925
We report a critical advance in the generation and characterization of peptoid hetero-oligomers. A library of sub-monomers with amine and carboxylate side-chains are combined in different sequences using microwave-assisted synthesis. Their sequence-s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1cf0294a9fd79496ad1c54ad1a338513
https://doi.org/10.1039/d1cc01992a
https://doi.org/10.1039/d1cc01992a
Autor:
Trideep, Rajale, Jacob C, Miner, Ryszard, Michalczyk, M Lisa, Phipps, Jurgen G, Schmidt, Robert D, Gilbertson, Robert F, Williams, Charlie E M, Strauss, Jennifer S, Martinez
Publikováno v:
Chemical communications (Cambridge, England). 57(77)
We report a critical advance in the generation and characterization of peptoid hetero-oligomers. A library of sub-monomers with amine and carboxylate side-chains are combined in different sequences using microwave-assisted synthesis. Their sequence-s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0196d27aace8e1e21923cb06f440c06e
https://pubmed.ncbi.nlm.nih.gov/34498621
https://pubmed.ncbi.nlm.nih.gov/34498621
Autor:
Taraka Dale, Jeremy M. Bingen, Scott P. Hennelly, Christopher W. Johnson, Ramesh K. Jha, Niju Narayanan, Gregg T. Beckham, Naresh Pandey, Theresa L. Kern, Charlie E. M. Strauss
Publikováno v:
ACS Synthetic Biology. 8:775-786
Product inhibition is a frequent bottleneck in industrial enzymes, and testing mutations to alleviate product inhibition via traditional methods remains challenging as many variants need to be tested against multiple substrate and product concentrati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8eca4454f164ead9b1c6524a3ed89ed0
https://doi.org/10.1021/acssynbio.8b00465
https://doi.org/10.1021/acssynbio.8b00465
Autor:
Allison Yankey, Andrew Bradbury, Kalifa Shabazz, Leslie Naranjo, Nileena Velappan, Charlie E. M. Strauss, Ramesh K. Jha
While natural protein-protein interactions have evolved to be induced by complex stimuli, rational design of interactions that can be switched-on-demand still remain challenging in the protein design world. Here, we demonstrate a computationally rede
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::93887ab32bf998c6b6f1ee79a8dd1574
https://doi.org/10.1101/2020.12.25.424402
https://doi.org/10.1101/2020.12.25.424402