Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Charlie Bayne"'
Publikováno v:
mSystems, Vol 9, Iss 10 (2024)
ABSTRACT Colibactin, a nonribosomal peptide/polyketide produced by pks+ Enterobacteriaceae, is a virulence factor and putative carcinogen that damages DNA by interstrand crosslinking (ICL). While the clb genes for colibactin biosynthesis have been id
Externí odkaz:
https://doaj.org/article/709ced73a3004793b13c52a1e8b4fa3a
Autor:
Andrew C. Tolonen, Nicholas Beauchemin, Charlie Bayne, Lingyao Li, Jie Tan, Jackson Lee, Brian M. Meehan, Jeffrey Meisner, Yves Millet, Gabrielle LeBlanc, Robert Kottler, Erdmann Rapp, Chris Murphy, Peter J. Turnbaugh, Geoffrey von Maltzahn, Christopher M. Liu, Johan E. T. van Hylckama Vlieg
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
Here, the authors characterize the gut microbiome fermentation properties and therapeutic potential of chemically diverse synthetic glycans (SGs), showing they promote specific shifts in taxonomic and metabolite profiles, and exhibit therapeutic bene
Externí odkaz:
https://doaj.org/article/fdaecafadbf44772b429bb30c4ca1053
Autor:
Consuelo Sauceda, Charlie Bayne, Khadijeh Sudqi, Antonio Gonzalez, Parambir S. Dulai, Rob Knight, David J. Gonzalez, Carlos G. Gonzalez
Publikováno v:
Gut Microbes, Vol 14, Iss 1 (2022)
ABSTRACTInflammatory Bowel Disease (IBD) is a chronic immune-mediated inflammatory disease of the gastrointestinal tract that is a growing public burden. Gut microbes and their interactions with hosts play a crucial role in disease pathogenesis and p
Externí odkaz:
https://doaj.org/article/8643a163209c48db8c8a21913912ff60
Publikováno v:
PLoS ONE, Vol 14, Iss 6, p e0217753 (2019)
Chlamydia trachomatis infections are the leading cause of sexually transmitted infections of bacterial origin. Lower genital tract infections are often asymptomatic, and therefore left untreated, leading to ascending infections that have long-term co
Externí odkaz:
https://doaj.org/article/930122fe97814a79836343ff414b06c1
Autor:
Yves A. Millet, Jeffrey Meisner, Jie Tan, Adarsh Jose, Eric Humphries, Kelsey J. Miller, Charlie Bayne, Megan McComb, Michael Giuggio, Camille M. Konopnicki, David B. Belanger, Lingyao Li, Han Yuan, Madeline Rosini, Hoa Luong, Jared Martin, Zhengzheng Pan, C. Ronald Kahn, Johan E.T. van Hylckama Vlieg
BackgroundIncreasing evidence indicates that an altered gut microbiome participates in the development of cardiometabolic syndrome and associated risk factors, such as insulin resistance, dyslipidemia, and obesity, and that targeting the gut microbio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::993eed8e5e811a71998422c0f115fd65
https://doi.org/10.1101/2022.04.04.487010
https://doi.org/10.1101/2022.04.04.487010
Autor:
Andrew C Tolonen, Nicholas Beauchemin, Charlie Bayne, Lingyao Li, Jie Tan, Jackson Lee, Brian Meehan, Jeffrey Meisner, Yves Millet, Gabrielle LeBlanc, Robert Kottler, Erdmann Rapp, Chris Murphy, Peter J Turnbaugh, Geoffrey von Maltzahn, Christopher M Liu, Johan ET van Hylckama Vlieg
Relative abundances of bacterial species in the gut microbiome have been linked to many diseases. Species of gut bacteria are ecologically differentiated by their abilities to metabolize different glycans, making glycan delivery a powerful way to alt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a37383a025aa126c2776dfb1c68c603c
https://doi.org/10.1101/2022.01.28.478269
https://doi.org/10.1101/2022.01.28.478269
Autor:
Andrew C. Tolonen, Nicholas Beauchemin, Charlie Bayne, Lingyao Li, Jie Tan, Jackson Lee, Brian M. Meehan, Jeffrey Meisner, Yves Millet, Gabrielle LeBlanc, Robert Kottler, Erdmann Rapp, Chris Murphy, Peter J. Turnbaugh, Geoffrey von Maltzahn, Christopher M. Liu, Johan E. T. van Hylckama Vlieg
Publikováno v:
Nature Communications
Nature communications, vol 13, iss 1
Nature communications, vol 13, iss 1
Relative abundances of bacterial species in the gut microbiome have been linked to many diseases. Species of gut bacteria are ecologically differentiated by their abilities to metabolize different glycans, making glycan delivery a powerful way to alt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8900fa1e2e98992294a6ee941616977
https://pubmed.ncbi.nlm.nih.gov/35273143
https://pubmed.ncbi.nlm.nih.gov/35273143
Publikováno v:
Proceedings of the National Academy of Sciences. 114:12039-12044
Membrane contact sites (MCS) are zones of contact between the membranes of two organelles. At MCS, specific proteins tether the organelles in close proximity and mediate the nonvesicular trafficking of lipids and ions between the two organelles. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3ce739c9ef5d59f7a7885a37a56a70de
https://doi.org/10.1073/pnas.1709060114
https://doi.org/10.1073/pnas.1709060114
Publikováno v:
PLoS ONE
PLoS ONE, Vol 14, Iss 6, p e0217753 (2019)
PLoS ONE, Vol 14, Iss 6, p e0217753 (2019)
Chlamydia trachomatis infections are the leading cause of sexually transmitted infections of bacterial origin. Lower genital tract infections are often asymptomatic, and therefore left untreated, leading to ascending infections that have long-term co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::401137365272418fb0ac1d3caf923bef
http://europepmc.org/articles/PMC6553856
http://europepmc.org/articles/PMC6553856
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 114(45)
Direct interorganelle contact, without fusion and through the formation of membrane contact sites (MCS), is crucial to maintain cell homeostasis and is exploited by intracellular vacuolar pathogens to establish their replication niche. At MCS, specif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9c2c603b1fb58ab4262de59fdbb472a1
https://pubmed.ncbi.nlm.nih.gov/29078338
https://pubmed.ncbi.nlm.nih.gov/29078338