Zobrazeno 1 - 10
of 112
pro vyhledávání: '"Charlie, Nichols"'
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
In-crystal fragment screening is a powerful tool to chemically probe the surfaces used by proteins to interact, and identify the chemical space worth exploring to design protein-protein inhibitors. A crucial prerequisite is the identification of a cr
Externí odkaz:
https://doaj.org/article/f3f8d14917424d07b7fb373f11ffd0b0
Autor:
Gian F, De Nicola, Rekha, Bassi, Charlie, Nichols, Mariana, Fernandez-Caggiano, Pelin Arabacilar, Golforoush, Dibesh, Thapa, Rhys, Anderson, Eva Denise, Martin, Sharwari, Verma, Jens, Kleinjung, Adam, Laing, Jonathan P, Hutchinson, Philip, Eaton, James, Clark, Michael S, Marber
Publikováno v:
JCI insight. 3(16)
Inhibiting MAPK14 (p38α) diminishes cardiac damage in myocardial ischemia. During myocardial ischemia, p38α interacts with TAB1, a scaffold protein, which promotes p38α autoactivation; active p38α (pp38α) then transphosphorylates TAB1. Previousl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e605d5f2e83ad8d47b505f93acf97da5
https://pubmed.ncbi.nlm.nih.gov/30135318
https://pubmed.ncbi.nlm.nih.gov/30135318
Autor:
Dibesh, Thapa, Charlie, Nichols, Rekha, Bassi, Eva Denise, Martin, Sharwari, Verma, Maria R, Conte, Vittorio, De Santis, Gian F, De Nicola, Michael S, Marber
Publikováno v:
Molecular and Cellular Biology
p38α mitogen-activated protein kinase is essential to cellular homeostasis. Two principal mechanisms to activate p38α exist. The first relies on dedicated dual-specificity kinases such as mitogen-activated protein kinase kinase (MAP2K) 3 (MKK3) or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::416907eb8e317fbe049ab366a93e33b5
https://pubmed.ncbi.nlm.nih.gov/29229647
https://pubmed.ncbi.nlm.nih.gov/29229647
Autor:
Valipour, Mehdi1 (AUTHOR), Di Giacomo, Silvia2 (AUTHOR), Di Sotto, Antonella2 (AUTHOR) antonella.disotto@uniroma1.it, Irannejad, Hamid3 (AUTHOR) antonella.disotto@uniroma1.it
Publikováno v:
International Journal of Molecular Sciences. May2023, Vol. 24 Issue 10, p8789. 32p.
Autor:
Flegr, Jaroslav1 flegr@cesnet.cz
Publikováno v:
PLoS ONE. 1/26/2016, Vol. 11 Issue 1, p1-12. 12p.
Publikováno v:
PLoS ONE. 10/23/2015, Vol. 10 Issue 10, p1-14. 14p.
Publikováno v:
Daily Mail. 1/14/2010, p70. 1p.