Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Charli B. Fant"'
Autor:
Yang Eric Guo, Brian J. Abraham, Tim-Michael Decker, Dylan J. Taatjes, Jenna K. Rimel, Phillip A. Sharp, Tong Ihn Lee, Charli B. Fant, John C. Manteiga, Krishna Shrinivas, Lena K. Afeyan, Benjamin R. Sabari, Richard A. Young, Jan-Hendrik Spille, Jonathan E. Henninger, Alessandra Dall’Agnese, Alicia V. Zamudio, Nancy M. Hannett, Ann Boija, Ibrahim I Cisse
Publikováno v:
Nature
The synthesis of pre-mRNA by RNA polymerase II (Pol II) involves the formation of a transcription initiation complex, and a transition to an elongation complex1–4. The large subunit of Pol II contains an intrinsically disordered C-terminal domain t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd05b7c69848ab64e299895bb7068c6d
https://doi.org/10.1038/s41586-019-1464-0
https://doi.org/10.1038/s41586-019-1464-0
Autor:
Jonathan D. Rubin, Jenna K. Rimel, Charli B. Fant, Zachary L. Maas, Dylan J. Taatjes, Meagan N. Esbin, Michael T. Marr, John Moir, Cecilia B. Levandowski, Kapil Gupta, Andrew Sawyer, Olivia Luyties, Robin D. Dowell, Imre Berger
Publikováno v:
Fant, C B, Levandowski, C B, Gupta, K, Maas, Z L, Moir, J, Rubin, J D, Sawyer, A, Esbin, M N, Rimel, J K, Luyties, O, Marr, M T, Berger, I, Dowell, R D & Taatjes, D J 2020, ' TFIID Enables RNA Polymerase II Promoter-Proximal Pausing ', Molecular Cell, vol. 78, no. 4, pp. 785-793.e8 . https://doi.org/10.1016/j.molcel.2020.03.008
Mol Cell
Mol Cell
Summary RNA polymerase II (RNAPII) transcription is governed by the pre-initiation complex (PIC), which contains TFIIA, TFIIB, TFIID, TFIIE, TFIIF, TFIIH, RNAPII, and Mediator. After initiation, RNAPII enzymes pause after transcribing less than 100 b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14f69ca34ab9220900fbd1069a208f44
https://doi.org/10.2139/ssrn.3429345
https://doi.org/10.2139/ssrn.3429345
Autor:
Yang Eric, Guo, John C, Manteiga, Jonathan E, Henninger, Benjamin R, Sabari, Alessandra, Dall'Agnese, Nancy M, Hannett, Jan-Hendrik, Spille, Lena K, Afeyan, Alicia V, Zamudio, Krishna, Shrinivas, Brian J, Abraham, Ann, Boija, Tim-Michael, Decker, Jenna K, Rimel, Charli B, Fant, Tong Ihn, Lee, Ibrahim I, Cisse, Phillip A, Sharp, Dylan J, Taatjes, Richard A, Young
Publikováno v:
Nature. 572(7770)
The synthesis of pre-mRNA by RNA polymerase II (Pol II) involves the formation of a transcription initiation complex, and a transition to an elongation complex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4b3f4b1e5f4ea6434ef2a8b38950629f
https://pubmed.ncbi.nlm.nih.gov/31734037
https://pubmed.ncbi.nlm.nih.gov/31734037
Autor:
Tong Ihn Lee, John C. Manteiga, Alicia V. Zamudio, Charli B. Fant, Richard A. Young, Dylan J. Taatjes, Jurian Schuijers, Ann Boija, Nancy M. Hannett, Lena K. Afeyan, Benjamin R. Sabari, Eliot L. Coffey, Alessandra Dall’Agnese, Jenna K. Rimel, Isaac A. Klein, Charles H. Li, Krishna Shrinivas, Yang Eric Guo, Brian J. Abraham
Publikováno v:
PMC
Gene expression is controlled by transcription factors (TFs) that consist of DNA-binding domains (DBDs) and activation domains (ADs). The DBDs have been well characterized, but little is known about the mechanisms by which ADs effect gene activation.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5565c69aec0f6124b264f1f66f88ae3f
https://pubmed.ncbi.nlm.nih.gov/30550782
https://pubmed.ncbi.nlm.nih.gov/30550782
Autor:
Charli B. Fant, Dylan J. Taatjes
Publikováno v:
Molecular Cell. 57:952-954
Estrogen receptor (ER) is a transcription factor critical for development, reproduction, metabolism and cancer. ER function hinges on its ability to recruit primary and secondary coactivators, yet structural information on the full-length receptor-co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::baee218010f3addba491b6d2b91e15ef
https://doi.org/10.1016/j.molcel.2015.03.001
https://doi.org/10.1016/j.molcel.2015.03.001