Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Charles Xing"'
Autor:
Gerhard Frey, Ana Paula G. Cugnetti, Haizhen Liu, Charles Xing, Christina Wheeler, Hwai Wen Chang, William J. Boyle, Jay M. Short
Publikováno v:
mAbs, Vol 16, Iss 1 (2024)
ABSTRACTEpithelial cell adhesion molecule (EpCAM) is a transmembrane glycoprotein that plays several roles in cancer biology. EpCAM is an attractive therapeutic target because of its expression in most solid tumors. However, targeting EpCAM has been
Externí odkaz:
https://doaj.org/article/7fc31e7a3b674b338e4ac1b2672d0edf
Autor:
Jing Wang, Wei Zhou, Ana Paula G Cugnetti, Mathew Lucas, Haizhen Liu, Charles Xing, Patty McNeely, Solimarie Joyner, Kyrie Johnson, Kathryn Woodard, Cathy Chang, Gerhard Frey, William J Boyle, Jay M Short
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/d933f3b17c434ab3ac5043d156c3ee2c
Autor:
Wei Zhou, Ana Paula G Cugnetti, Mathew Lucas, Haizhen Liu, Charles Xing, Solimarie Joyner, Kyrie Johnson, Kathryn Woodard, Cathy Chang, Gerhard Frey, William J Boyle, Jay M Short, Patricia McNeeley
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/c6858652b2444bd089373159245edfe0
Autor:
Amal M. Osman, Sutapa Mukherjee, Thomas J. Altree, Martina Delbeck, Doris Gehring, Michael Hahn, Tina Lang, Charles Xing, Thomas Muller, Gerrit Weimann, Danny J. Eckert
Publikováno v:
Chest. 163:953-965
Autor:
Ana Paula Cugnetti, Haizhen Liu, Patricia McNeeley, Christina Wheeler, Matthew Lucas, Charles Xing, Solmarie Joyner, Kyrie Johnson, Kathryn Woodard, Wei Zhou, Cathy Chang, Gerhard Frey, William J. Boyle, Jay M. Short
Publikováno v:
Cancer Research. 83:1871-1871
Human epidermal growth factor receptor 2 (HER2) is overexpressed in multiple cancers and is associated with poor prognosis. Despite the outstanding improvement in survival with the introduction of anti-HER2 therapies, therapeutic benefit is limited b
Autor:
Matthew Lucas, Ana Paula Cugnetti, Haizhen Liu, Charles Xing, Jing Wang, Patricia McNeeley, Christina Wheeler, Solmarie Joyner, Kyrie Johnson, Kathryn Woodard, Wei Zhou, Cathy Chang, Gerhard Frey, William J. Boyle, Jay M. Short
Publikováno v:
Cancer Research. 83:1879-1879
Nectin-4 is a Ca2+ independent immunoglobulin-like protein that is primarily involved in cell-cell adhesion. Nectin-4 is overexpressed in several tumor types, including breast, lung, urothelial, colorectal, pancreatic, and ovarian cancers. Overexpres
Autor:
Amal M, Osman, Sutapa, Mukherjee, Thomas J, Altree, Martina, Delbeck, Doris, Gehring, Michael, Hahn, Tina, Lang, Charles, Xing, Thomas, Muller, Gerrit, Weimann, Danny J, Eckert
Publikováno v:
Chest.
Potassium channel inhibition has been identified in animal models as a potential target to increase pharyngeal dilator muscle activity and to treat OSA. However, these findings have not yet been translated to humans.Does a novel, potent, TWIK-related
Autor:
Malcolm Kohler, Charles Xing, John Stradling, A. Chiang, Gerrit Weimann, Sigrun Unger, Chris D. Turnbull, Rudolf Finger, Thomas Gaisl, Peter A. Cistulli, Danny J. Eckert, Sophie West
Publikováno v:
The European Respiratory Journal
article-version (VoR) Version of Record
article-version (VoR) Version of Record
For obstructive sleep apnoea (OSA), few mechanical treatment options are available and no pharmacotherapy is approved [1–3]. However, safe and efficacious pharmacotherapy would have substantial appeal for many people with OSA.
BAY 2253651 is a
BAY 2253651 is a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a81f2d8fc0f97a978292113c7989bc0
https://www.zora.uzh.ch/id/eprint/211860/
https://www.zora.uzh.ch/id/eprint/211860/
Autor:
Haizhen Liu, Hwai Wen Chang, Jay M. Short, Lawrence Steinman, Charles Xing, Gerhard Frey, William J. Boyle
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance On-target, off-tumor toxicity of anti-CTLA4 checkpoint inhibitors leads to severe adverse events, restricting therapeutic efficacy. We engineered anti-CTLA4 antibodies and generated a new class of antibodies referred to as conditionally
Autor:
Christina Wheeler, Jing Wang, Haizhen Liu, Ana Paula G. Cugnetti, William J. Boyle, Jay M. Short, Cathy Chang, Charles Xing, Gerhard Frey, Matthew Lucas
Publikováno v:
Cancer Research. 81:1870-1870
The use of CD3/target bispecific molecules has great therapeutic potential in oncology. This potential, however, is diminished due to severe cytokine release effects as well as serious on-target off-tumor toxicities. Conditionally Active Biologic (CA