Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Charles W. Kimbrough"'
Autor:
Lacey R. McNally, William E. Grizzle, Selwyn M. Vickers, Kelly M. McMasters, Neal C. Burton, Bigya R. Khanal, Matthew Zeiderman, Anil Khanal, Charles W. Kimbrough
Supplemental Figure Legend from Targeting Acidity in Pancreatic Adenocarcinoma: Multispectral Optoacoustic Tomography Detects pH-Low Insertion Peptide Probes In Vivo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60d8bfc5eb26fe57184f8b1d091ee434
https://doi.org/10.1158/1078-0432.22460582
https://doi.org/10.1158/1078-0432.22460582
Autor:
Lacey R. McNally, William E. Grizzle, Selwyn M. Vickers, Kelly M. McMasters, Neal C. Burton, Bigya R. Khanal, Matthew Zeiderman, Anil Khanal, Charles W. Kimbrough
Supplemental Figure S3: Elliptical 3.5 mm2 ROIs were drawn based upon anatomical location and this size was maintained for relative quantitation of signal accumulation in the pancreas tumor, kidney, and liver. Because the liver and kidney are more ea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::105cee4a29629c466be714154a8cb874
https://doi.org/10.1158/1078-0432.22460573.v1
https://doi.org/10.1158/1078-0432.22460573.v1
Autor:
Lacey R. McNally, William E. Grizzle, Selwyn M. Vickers, Kelly M. McMasters, Neal C. Burton, Bigya R. Khanal, Matthew Zeiderman, Anil Khanal, Charles W. Kimbrough
Supplemental Figure S1: (A) Uv-Vis absorbance of K7-750 and V7-750 probes at 40 μM peptide concentration. Absorbance peak at 280 nm shows the peptide peak, while absorbance peak at 750 nm shows the dye peak. (B) Normalized absorbance of V7-750, K7-7
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a95578aa9659d69aa2b3425b9ef8bf1
https://doi.org/10.1158/1078-0432.22460579
https://doi.org/10.1158/1078-0432.22460579
Autor:
Lacey R. McNally, William E. Grizzle, Selwyn M. Vickers, Kelly M. McMasters, Neal C. Burton, Bigya R. Khanal, Matthew Zeiderman, Anil Khanal, Charles W. Kimbrough
Supplemental Figure S5 The movie clip demonstrates spectrally unmixed oxy-hemoglobin (red color, left panel), deoxy-hemoglobin (blue color, middle panel), and V7-750 probe (green color, right panel) which were obtained using MSOT imaging as in Figure
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62f1541dab2228b3ad7dca14d937621a
https://doi.org/10.1158/1078-0432.22460567.v1
https://doi.org/10.1158/1078-0432.22460567.v1
Autor:
Lacey R. McNally, William E. Grizzle, Selwyn M. Vickers, Kelly M. McMasters, Neal C. Burton, Bigya R. Khanal, Matthew Zeiderman, Anil Khanal, Charles W. Kimbrough
Background: pH-low insertion peptides (pHLIP) can serve as a targeting moiety that enables pH-sensitive probes to detect solid tumors. Using these probes in conjunction with multispectral optoacoustic tomography (MSOT) is a promising approach to impr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::306b5e82c402545907b439a12d9959b6
https://doi.org/10.1158/1078-0432.c.6524531
https://doi.org/10.1158/1078-0432.c.6524531
Autor:
Lacey R. McNally, William E. Grizzle, Selwyn M. Vickers, Kelly M. McMasters, Neal C. Burton, Bigya R. Khanal, Matthew Zeiderman, Anil Khanal, Charles W. Kimbrough
Supplemental Figure S6: Dosimetry analysis demonstrates accumulation of V7-750 and K7-750 ex vivo in the liver, kidney, and pancreas tumor from planar fluorescent images.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69bcd2efdd56837154df6f87522a62ff
https://doi.org/10.1158/1078-0432.22460564.v1
https://doi.org/10.1158/1078-0432.22460564.v1
Autor:
Lacey R. McNally, William E. Grizzle, Selwyn M. Vickers, Kelly M. McMasters, Neal C. Burton, Bigya R. Khanal, Matthew Zeiderman, Anil Khanal, Charles W. Kimbrough
Supplemental Figure S2: As the K7-750 probe did not bind to pancreas tumors, deoxy-hemoglobin signal was utilized to denote the location of the pancreas tumors. Orthogonal views of deoxy-hemoglobin signal indicate the location of the pancreatic tumor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19776a574bdab58add47b3ab551a63d3
https://doi.org/10.1158/1078-0432.22460576
https://doi.org/10.1158/1078-0432.22460576
Autor:
Joshua H. Winer, Laura A. Lambert, Mustafa Raoof, Adriana C. Gamboa, Harveshp Mogal, Keith Fournier, Travis E. Grotz, Jordan M. Cloyd, Jula Veerapong, Michael K. Turgeon, Sean P. Dineen, Charles W. Kimbrough, Shishir K. Maithel, Mohammad Y. Zaidi, Rachel M. Lee, Sameer H. Patel, Benjamin D. Powers, Nadege Fackche, Callisia N. Clarke, Charles A. Staley, Sean Ronnekleiv-Kelly, Jonathan B. Greer
Publikováno v:
Ann Surg Oncol
BACKGROUND. Patient age is a significant factor in preoperative selection for major abdominal surgery. The association of age, tumor biology, and postoperative outcomes in patients undergoing cytoreductive surgery (CRS) and hyperthermic intraperitone
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f06ab929f6b038d5844a150dbacbcd85
https://doi.org/10.1245/s10434-020-08538-y
https://doi.org/10.1245/s10434-020-08538-y
Autor:
Mustafa Raoof, Sameer H. Patel, Callisia N. Clarke, Travis E. Grotz, Laura A. Lambert, Vikrom K. Dhar, Courtney Pokrzywa, Jordan M. Cloyd, Keith Fournier, Daniel E. Abbott, Charles W. Kimbrough, Benjamin D. Powers, Shishir K. Maithel, Harveshp Mogal, Jennifer L. Leiting, Seth Felder, Jonathan B. Greer, Ryan J. Hendrix, Byrne Lee, Charles A. Staley, Jula Veerapong, Joel M. Baumgartner, Sean P. Dineen, Andrew J. Lee, Fabian M. Johnston, Sophie Dessureault, Iman Imanirad
Publikováno v:
Annals of Surgical Oncology. 27:4883-4891
Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (CRS/HIPEC) is offered to select patients with peritoneal metastases. In instances of recurrence/progression, a repeat CRS/HIPEC may be considered. The perioperative morbidity and th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44af4b1bc0269002afeb33ca558f1298
https://doi.org/10.1245/s10434-020-08482-x
https://doi.org/10.1245/s10434-020-08482-x
Autor:
Laura A. Lambert, Callisia N. Clarke, Travis E. Grotz, Ryan J. Hendrix, Christopher J. LaRocca, Daniel E. Abbott, Benjamin D. Powers, Maria C. Russell, Adriana C. Gamboa, Joel M. Baumgartner, Keith Fournier, Charles A. Staley, Kara Vande Walle, Sean P. Dineen, Sameer H. Patel, Jeffrey J. Sussman, Jordan M. Cloyd, Charles W. Kimbrough, Nadege Fackche, Shishir K. Maithel, Rachel M. Lee, Mohammad Y. Zaidi, Jennifer L. Leiting, Shelby Speegle, Jula Veerapong, Andrew J. Lee, Fabian M. Johnston, Mustafa Raoof
Publikováno v:
Clinical Colorectal Cancer. 19:e1-e7
Radiographic prediction of peritoneal carcinomatosis index (PCI) can improve patient selection for cytoreductive surgery. We aimed to determine the correlation of computed tomography (CT)-predicted PCI (CT-PCI) and magnetic resonance imaging (MRI)-pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03ef7f768df08f3bbd8cf9b0d7e26f70
https://doi.org/10.1016/j.clcc.2019.12.002
https://doi.org/10.1016/j.clcc.2019.12.002