Zobrazeno 1 - 10
of 116
pro vyhledávání: '"Charles W Penn"'
Autor:
Martin J Sergeant, Chrystala Constantinidou, Tristan A Cogan, Michael R Bedford, Charles W Penn, Mark J Pallen
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e91941 (2014)
Chickens are major source of food and protein worldwide. Feed conversion and the health of chickens relies on the largely unexplored complex microbial community that inhabits the chicken gut, including the ceca. We have carried out deep microbial com
Externí odkaz:
https://doaj.org/article/e63d787612ad4fe2973bbc98b3b6db68
Autor:
Lewis E H Bingle, Chrystala Constantinidou, Robert K Shaw, Md Shahidul Islam, Mala Patel, Lori A S Snyder, David J Lee, Charles W Penn, Stephen J W Busby, Mark J Pallen
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e80160 (2014)
The type III protein secretion system is an important pathogenicity factor of enteropathogenic and enterohaemorrhagic Escherichia coli pathotypes. The genes encoding this apparatus are located on a pathogenicity island (the locus of enterocyte efface
Externí odkaz:
https://doaj.org/article/4d64dbfa51c84bb2a541a793e09ff665
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e53115 (2013)
Mammalian intestinal microbiota remain poorly understood despite decades of interest and investigation by culture-based and other long-established methodologies. Using high-throughput sequencing technology we now report a detailed analysis of canine
Externí odkaz:
https://doaj.org/article/f2bafaa1742047dc9bbc14902e49f962
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e38094 (2012)
The analysis of 16S-rDNA sequences to assess the bacterial community composition of a sample is a widely used technique that has increased with the advent of high throughput sequencing. Although considerable effort has been devoted to identifying the
Externí odkaz:
https://doaj.org/article/e3e300cf6edd48d3b4da1c4f0b67e4be
Autor:
Alan McNally, Gemma Clark, James Hale, Chrystala Constantinidou, Vivienne Weston, Mark Achtman, Konrad Paszkiewicz, Charles W. Penn
Publikováno v:
Journal of Antimicrobial Chemotherapy. 67:868-877
Objectives To determine variation at the genome level in Escherichia coli ST131 clinical isolates previously shown to be phenotypically diverse. Methods The genomes of 10 ST131 isolates extensively characterized in previous studies were sequenced usi
Autor:
Susan Stokoe, Raúl Pacheco-Gómez, Hannah J. England, Julia Kraemer, Matthew R. Hicks, Charles W. Penn, Alison Rodger, Timothy R. Dafforn, John M. Ward, Emma Stanley
Publikováno v:
Analytical Chemistry. 84:91-97
Biomolecular detection has for a long time depended on a relatively small number of established methodologies. Many of these depend on the detection of a ligand-antibody complex using some kind of optical technique, e.g., chemiluminescence. Before th
Publikováno v:
Journal of Proteome Research
Glycosylation of flagellin in Campylobacter jejuni is essential for motility and virulence. It is well-known that flagellin from C. jejuni 81−176 is glycosylated by pseudaminic acid and its acetamidino derivative, and that Campylobactor coli VC167
Autor:
S. James L. Cariss, Chrystala Constantinidou, Mala D. Patel, Jon L. Hobman, Yuiko Takebayashi, Charles W. Penn, Matthew B. Avison
Publikováno v:
Journal of Bacteriology. 192:3329-3336
Colicin E2-tolerant (known as Cet2) Escherichia coli K-12 mutants overproduce an inner membrane protein, CreD, which is believed to cause the Cet2 phenotype. Here, we show that overproduction of CreD in a Cet2 strain results from hyperactivation of t
Autor:
Charles W. Penn, S. James L. Cariss, G. Aida Hidalgo-Arroyo, Matthew B. Avison, Jon L. Hobman, Mala D. Patel, Chrystala Constantinidou
Publikováno v:
Journal of Bacteriology. 189:8786-8792
The use of whole-genome microarrays for monitoring mutagenized or otherwise engineered genetic derivatives is a potentially powerful tool for checking genomic integrity. Using comparative genomic hybridization of a number of unrelated, directed delet
Autor:
Jason Hinds, Gemma L. Marsden, Aparna Jagannathan, Charles W. Penn, Chrystala Constantinidou, Brendan W. Wren, Susan M. Turner, David J. Studholme, Ken Laing, Nahid Kamal, Nick Dorrell
Publikováno v:
Microbiology. 153:3099-3111
A previously unannotated, putative fliK gene was identified in the Campylobacter jejuni genome based on sequence analysis; deletion mutants in this gene had a 'polyhook' phenotype characteristic of fliK mutants in other genera. The mutants greatly ov